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    Perfect, thanks!<br>
    <br>
    <div class="moz-cite-prefix">On 08/01/2012 03:28 PM, Donald Tournier
      wrote:<br>
    </div>
    <blockquote
cite="mid:CAPP9hqRtj10B3NxOzU2vtz-CNrcnoqZ8Zpb6+Apc5r6rEhESeg@mail.gmail.com"
      type="cite">
      <div class="csl-bib-body"
        style="line-height:1.35;padding-left:2em">
        <div class="csl-entry">Hi Peter,</div>
        <div class="csl-entry"><br>
        </div>
        <div class="csl-entry">This is probably what you're looking for:</div>
        <div class="csl-entry"><br>
        </div>
        <div class="csl-entry">Tournier J, Calamante F, Connelly A
          (2012). MRtrix: Diffusion tractography in crossing fiber
          regions. International Journal of Imaging Systems and
          Technology 22: 53–66.</div>
        <span class="Z3988"
title="url_ver=Z39.88-2004&amp;ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzotero.org%3A2&amp;rft_id=info%3Adoi%2F10.1002%2Fima.22005&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.atitle=MRtrix%3A%20Diffusion%20tractography%20in%20crossing%20fiber%20regions&amp;rft.jtitle=International%20Journal%20of%20Imaging%20Systems%20and%20Technology&amp;rft.volume=22&amp;rft.issue=1&amp;rft.aufirst=J%E2%80%90Donald&amp;rft.aulast=Tournier&amp;rft.au=J%E2%80%90Donald%20Tournier&amp;rft.au=Fernando%20Calamante&amp;rft.au=Alan%20Connelly&amp;rft.date=2012-03-01&amp;rft.pages=53-66&amp;rft.spage=53&amp;rft.epage=66&amp;rft.issn=1098-1098"></span></div>
      <div><br>
      </div>
      <div>Cheers,</div>
      <div><br>
      </div>
      <div>Donald.</div>
      <div><br>
      </div>
      <br>
      <div class="gmail_quote">On 1 August 2012 23:25, Peter Neher <span
          dir="ltr">&lt;<a moz-do-not-send="true"
            href="mailto:p.neher@dkfz-heidelberg.de" target="_blank">p.neher@dkfz-heidelberg.de</a>&gt;</span>
        wrote:<br>
        <blockquote class="gmail_quote" style="margin:0 0 0
          .8ex;border-left:1px #ccc solid;padding-left:1ex">
          <div bgcolor="#FFFFFF" text="#000000"> Hi Donald,<br>
            <br>
            thanks for your answers! Is there any publication or
            something else that describes your probabilistic tracking
            implementation in more detail? <br>
            <br>
            Best<span class="HOEnZb"><font color="#888888"><br>
                Peter</font></span>
            <div>
              <div class="h5"><br>
                <br>
                <div>On 08/01/2012 02:03 AM, Donald Tournier wrote:<br>
                </div>
                <blockquote type="cite">Hello again,
                  <div><br>
                    <div class="gmail_quote">
                      <blockquote class="gmail_quote" style="margin:0 0
                        0 .8ex;border-left:1px #ccc
                        solid;padding-left:1ex">
                        <div bgcolor="#FFFFFF" text="#000000">I have
                          some questions regarding the parameters of
                          streamtrack:<br>
                          <ol>
                            <li>Should it basically be the same to use a
                              0.2 thresholded FA image as -mask input as
                              to apply a -cutoff 0.2? Because it is not.
                              There seem to be fibers present in low FA
                              regions if  I use the -cutoff parameter.
                              It does change something, but I am not
                              sure what exactly :)</li>
                          </ol>
                        </div>
                      </blockquote>
                      <div>Not quite the same, as you found out. The
                        -cutoff applies to the FA as computed after
                        tri-linear interpolation of the raw DWIs to the
                        current point. For the mask, the cutoff point is
                        the 0.5 level after tri-linear interpolation
                        (you can use nearest-neighbour interpolation if
                        you need to using the -nomaskinterp option).
                        That will lead to the FA=0.2 level being in a
                        different position than the mask=0.5 level, and
                        in many cases, tracks will traverse regions
                        where the mask is zero, simply because they
                        avoid those parts of the voxel where the FA is
                        below 0.2 after interpolation.</div>
                      <div> </div>
                      <blockquote class="gmail_quote" style="margin:0 0
                        0 .8ex;border-left:1px #ccc
                        solid;padding-left:1ex">
                        <div bgcolor="#FFFFFF" text="#000000">
                          <ol>
                            <li>How is the -num parameter applied
                              internally? Don't you just seed in every
                              voxel of the mask image? <br>
                            </li>
                          </ol>
                        </div>
                      </blockquote>
                      <div>Nope. Seed points are generated randomly and
                        uniformly from within all seed regions, in
                        continuous 3D space. Even within a single voxel,
                        the seed points will be distributed uniformly
                        within its volume, rather than all starting from
                        the centre of it. Streamlines will be generated
                        until the number specified has been reached, or
                        the -maxnum number has been reached (by default,
                        this is 100x num). If you need to make sure you
                        use exactly N seed points, set both -num and
                        -maxnum to N.</div>
                      <div> </div>
                      <blockquote class="gmail_quote" style="margin:0 0
                        0 .8ex;border-left:1px #ccc
                        solid;padding-left:1ex">
                        <div bgcolor="#FFFFFF" text="#000000">
                          <ol>
                            <li>If I use the probabilistic version, how
                              many times is the trajectory originating
                              from one seed point sampled and how is the
                              result combined into one final fiber?</li>
                          </ol>
                        </div>
                      </blockquote>
                      <div>Once. Every streamline starts from a fresh
                        seed.</div>
                      <div><br>
                      </div>
                      <div>Cheers,</div>
                      <div><br>
                        Donald.</div>
                      <div><br>
                      </div>
                      <div> </div>
                      <blockquote class="gmail_quote" style="margin:0 0
                        0 .8ex;border-left:1px #ccc
                        solid;padding-left:1ex">
                        <div bgcolor="#FFFFFF" text="#000000">
                          <ol>
                          </ol>
                          <p>Thanks in advance!<span><font
                                color="#888888"><br>
                              </font></span></p>
                          <span><font color="#888888">
                              <p>Peter<br>
                              </p>
                              <pre cols="72">-- 
Dipl.-Inform. Peter Neher
German Cancer Research Centre
(DKFZ, Deutsches Krebsforschungszentrum in der Helmholtz-Gemeinschaft, Stiftung des öffentlichen Rechts)
Division of Medical and Biological Informatics
Im Neuenheimer Feld 280, D-69120 Heidelberg

Phone: 49-(0)6221-42-3552, Fax: 49-(0)6221-42-2345
E-Mail: <a moz-do-not-send="true" href="mailto:p.neher@dkfz-heidelberg.de" target="_blank">p.neher@dkfz-heidelberg.de</a>, Web: <a moz-do-not-send="true" href="http://www.dkfz.de" target="_blank">www.dkfz.de</a>

The information contained in this message may be confidential and legally protected under applicable law. The message is intended solely for the addressee(s). If you are not the intended recipient, you are hereby notified that any use, forwarding, dissemination, or reproduction of this message is strictly prohibited and may be unlawful. If you are not the intended recipient, please contact the sender by return e-mail and destroy all copies of the original message.</pre>
                            </font></span></div>
                        <br>
                        _______________________________________________<br>
                        Mrtrix-discussion mailing list<br>
                        <a moz-do-not-send="true"
                          href="mailto:Mrtrix-discussion@www.nitrc.org"
                          target="_blank">Mrtrix-discussion@www.nitrc.org</a><br>
                        <a moz-do-not-send="true"
                          href="http://www.nitrc.org/mailman/listinfo/mrtrix-discussion"
                          target="_blank">http://www.nitrc.org/mailman/listinfo/mrtrix-discussion</a><br>
                        <br>
                      </blockquote>
                    </div>
                    <br>
                    <br clear="all">
                    <div><br>
                    </div>
                    -- <br>
                    Jacques-Donald Tournier (PhD)<br>
                    Brain Research Institute, Melbourne, Australia<br>
                    Tel: +61 (0)3 9035 7033<br>
                  </div>
                </blockquote>
                <br>
                <pre cols="72">-- 
Dipl.-Inform. Peter Neher
German Cancer Research Centre
(DKFZ, Deutsches Krebsforschungszentrum in der Helmholtz-Gemeinschaft, Stiftung des öffentlichen Rechts)
Division of Medical and Biological Informatics
Im Neuenheimer Feld 280, D-69120 Heidelberg

Phone: 49-(0)6221-42-3552, Fax: 49-(0)6221-42-2345
E-Mail: <a moz-do-not-send="true" href="mailto:p.neher@dkfz-heidelberg.de" target="_blank">p.neher@dkfz-heidelberg.de</a>, Web: <a moz-do-not-send="true" href="http://www.dkfz.de" target="_blank">www.dkfz.de</a>

The information contained in this message may be confidential and legally protected under applicable law. The message is intended solely for the addressee(s). If you are not the intended recipient, you are hereby notified that any use, forwarding, dissemination, or reproduction of this message is strictly prohibited and may be unlawful. If you are not the intended recipient, please contact the sender by return e-mail and destroy all copies of the original message.</pre>
              </div>
            </div>
          </div>
        </blockquote>
      </div>
      <br>
      <br clear="all">
      <div><br>
      </div>
      -- <br>
      Jacques-Donald Tournier (PhD)<br>
      Brain Research Institute, Melbourne, Australia<br>
      Tel: +61 (0)3 9035 7033<br>
    </blockquote>
    <br>
    <pre class="moz-signature" cols="72">-- 
Dipl.-Inform. Peter Neher
German Cancer Research Centre
(DKFZ, Deutsches Krebsforschungszentrum in der Helmholtz-Gemeinschaft, Stiftung des öffentlichen Rechts)
Division of Medical and Biological Informatics
Im Neuenheimer Feld 280, D-69120 Heidelberg

Phone: 49-(0)6221-42-3552, Fax: 49-(0)6221-42-2345
E-Mail: <a class="moz-txt-link-abbreviated" href="mailto:p.neher@dkfz-heidelberg.de">p.neher@dkfz-heidelberg.de</a>, Web: <a class="moz-txt-link-abbreviated" href="http://www.dkfz.de">www.dkfz.de</a>

The information contained in this message may be confidential and legally protected under applicable law. The message is intended solely for the addressee(s). If you are not the intended recipient, you are hereby notified that any use, forwarding, dissemination, or reproduction of this message is strictly prohibited and may be unlawful. If you are not the intended recipient, please contact the sender by return e-mail and destroy all copies of the original message.</pre>
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