Agreed. I will not use CSD with multi-shell data. However, given that the tensor model is sufficient for the tract I am interested in (fornix), that CSF suppression is crucial for this study, and that FLAIR is not working well for me right now, I will still use this acquisition, as it eliminates signal from CSF due to its very high ADC. FYI, my imaging protocol also includes another, single-shell, multi-direction acquisition specifically for CSD.<br>
<br>Luis<br>
<br><br><div class="gmail_quote">On Thu, Nov 15, 2012 at 7:31 PM, Donald Tournier <span dir="ltr"><<a href="mailto:d.tournier@brain.org.au" target="_blank">d.tournier@brain.org.au</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">
Hi everyone,<div><br></div><div>The DTI fit in MRtrix should handle multiple b-values fine. The CSD approach however cannot currently handle such data, as Thijs correctly stated. Luis, I'm surprised that you manage to get convincing results simply by stripping off the b=0 image, since it is ignored by csdeconv anyway (unless you use the -normalise option which is not recommended). In any case, it is definitely not designed to handle multiple b-values, so I would not advise planning your study around it...</div>
<div><br></div><div>Cheers,</div><div><br></div><div>Donald.</div><div><br></div><div><br></div></blockquote></div><br>