<p dir="ltr">Hi Alessandro,</p>
<p dir="ltr">Well, at heart AFD really is only the amplitude of the FOD along the fibre direction of interest - actually, technically it's the integral of the FOD over the FOD peak. You can compute the FOD amplitude in the old version, but all the tools to compute the integral are in MRtrix3...</p>
<p dir="ltr">Besides, to really do AFD justice requires some fairly complex preprocessing steps to ensure values can be compared across subjects, which we still haven't documented properly. They're all currently implemented in MRtrix3 - this is where all the development effort is going. While you probably could hack something together using the old version, my recommendation would be to upgrade and wait for the documentation to be updated (hopefully not too long after the ISMRM...).</p>
<p dir="ltr">Even if you do want to stick with the old version, the steps required will at least be documented on the MRtrix3 wiki, so you'll be able to see for yourself how feasible this might be...</p>
<p dir="ltr">Cheers,<br>
Donald</p>
<div class="gmail_quote">On 28 May 2015 5:41 pm, "Alessandro Calamuneri" <<a href="mailto:alecalamuneri@gmail.com">alecalamuneri@gmail.com</a>> wrote:<br type="attribution"><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div><div>Hi Donald,<br></div>thanks for quick answering..<br>Given I am using old mrtrix version (0.2), what could be a pipeline for calculating AFD?<br><br></div><div>Thanks,<br></div><div>Alessandro<br></div><div class="gmail_extra"><br><div class="gmail_quote">2015-05-28 18:03 GMT+02:00 J-Donald Tournier <span dir="ltr"><<a href="mailto:jdtournier@gmail.com" target="_blank">jdtournier@gmail.com</a>></span>:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><p dir="ltr">Hi Alessandro,</p>
<p dir="ltr">Yes, that particular question has come up many times over the years... I think we have a suitable answer now: apparent fibre density (<a href="http://www.ncbi.nlm.nih.gov/pubmed/22036682" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/22036682</a>). And this will probably be improved further using multi-tissue CSD (<a href="http://www.ncbi.nlm.nih.gov/pubmed/25109526)." target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/25109526).</a>..</p>
<p dir="ltr">Hope this answers your question.<br>
Cheers,<br>
Donald</p>
<div class="gmail_quote"><div><div>On 28 May 2015 4:00 pm, "Alessandro Calamuneri" <<a href="mailto:alecalamuneri@gmail.com" target="_blank">alecalamuneri@gmail.com</a>> wrote:<br type="attribution"></div></div><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div><div><div dir="ltr"><div>Hi mrtrix experts,<br><br></div>I would like to know whether there exists a csd based measure that might be considered the equivalent of Fractional Anisotrpy.<br clear="all"><div><div><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><br></div><div>Best Regards,<br></div><div>Alessandro<br></div><div dir="ltr"><div><br></div></div></div></div></div></div>
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