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<span style="font-size:12.0pt;color:black"> <span style="border:none windowtext 1.0pt;padding:0in"><img width="88" height="88" style="width:.9166in;height:.9166in" id="_x0000_i1025" src="cid:image001.png@01D7429E.E440D8C0"></span></span><span style="font-size:12.0pt;border:none windowtext 1.0pt;padding:0in">
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<b><span style="font-size:16.0pt;font-family:"Arial",sans-serif;color:#00B0F0">ReproNim: A Center for Neuroimaging Computation</span></b><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#F3901D">ReproNim 'First Thursdays' Drop-In Office Hours -</span><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#212121"> </span><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#E97132">Thursday,
October 3, 2024 </span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Aptos",sans-serif"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:#212121">All are welcome to our <b>ReproNim Office Hours Program! </b>Do you have a reproducibility question, challenge, or problem? </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"> </span><span style="font-size:11.0pt;font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:#212121">Our next Drop-In Session will be Thursday,
</span></b><b><span style="font-family:"Arial",sans-serif">October 3<span style="color:#212121">, 2024</span></span></b><span style="font-family:"Arial",sans-serif;color:#212121">,
</span><span style="font-family:"Arial",sans-serif">from <b>1-2pm ET<span style="color:#212121">, </span></b><span style="color:#212121">via Gathertown</span><span style="color:black">.</span></span><o:p></o:p></p>
<ul style="margin-top:0in" type="disc">
<li class="MsoNormal" style="color:#212121;mso-list:l0 level1 lfo1"><b><span style="font-family:"Arial",sans-serif;color:black">Gathertown </span></b><u><span style="font-family:"Arial",sans-serif;color:black"><a href="https://t.co/uE0qveSTC5?amp=1" target="loopstyle_link" data-loopstyle="link" title="Original URL:
https://t.co/uE0qveSTC5?amp=1
Click to follow link."><span style="color:#0078D7">https://gather.town/app/ESJPNXX7CVirKett/nmind</span></a></span></u><o:p></o:p></li></ul>
<p class="MsoNormal" style="margin-left:.5in"><span style="font-family:"Arial",sans-serif;color:#212121"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">-If you have any difficulty connecting, please email David Kennedy (<a href="mailto:david.kennedy@umassmed.edu"><span style="color:#0078D7">david.kennedy@umassmed.edu</span></a>)
or Julie Bates (<a href="mailto:julianna.bates@umassmed.edu"><span style="color:#0078D7">julianna.bates@umassmed.edu</span></a>)</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">-If you sign in to Gathertown but don't see ReproNim folks, please look for 'ReproNim Dave'
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<span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#F3901D">ReproNim</span><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#E97132"> 'First Fridays' Webinar
<b>– Friday,</b></span><b><span style="font-size:14.0pt;font-family:"Arial",sans-serif">
<span style="color:#E97132">October 4</span></span></b><span style="font-size:14.0pt;font-family:"Arial",sans-serif;color:#E97132">, at
<b>2pm Eastern Time</b></span><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Our special guest speaker this month is
<span style="color:#0070C0"><a href="https://childmind.org/bio/michael-p-milham-md-phd/">Mike Milham</a></span>, who joins us from the Child Mind Institute, for a presentation on some of his very recent work (<i><span style="color:#0070C0"><a href="https://www.nature.com/articles/s41562-024-01942-4">Nature
Human Behavior<span style="font-style:normal">, August 2024</span></a></span></i>):
<span style="color:#212121">"<i>Moving beyond processing- and analysis-related variation in resting-state functional brain imaging.</i>"</span> [See Abstract below]</span><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Mike’s work spans brain development, child and adolescent psychiatry, and the advancement of neuroimaging data sharing initiatives and implementation of big data all in the service of understanding
how functional & structural connectivity in brain may underlie mental illness. Among numerous leadership positions, he is the founding Director for the CMI Center for the Developing Brain, and Director of the Healthy Brain Network. He has pioneered innovative
initiatives, including co-founding the 1000 Functional Connectomes Project, and that project’s International Neuroimaging Data-Sharing Initiative.</span><o:p></o:p></p>
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<p class="MsoNormal"><i><span style="font-family:"Arial",sans-serif">Abstract</span></i><span style="font-family:"Arial",sans-serif">
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">When fields lack consensus standard methods and accessible ground truths, reproducibility can be more of an ideal than a reality. Such has been the case for functional neuroimaging, where there
exists a sprawling space of tools and processing pipelines. We provide a critical evaluation of the impact of differences across five independently developed minimal preprocessing pipelines for functional magnetic resonance imaging. We show that, even when
handling identical data, interpipeline agreement was only moderate, critically shedding light on a factor that limits cross-study reproducibility. We show that low interpipeline agreement can go unrecognized until the reliability of the underlying data is
high, which is increasingly the case as the field progresses. Crucially we show that, when interpipeline agreement is compromised, so too is the consistency of insights from brain-wide association studies. We highlight the importance of comparing analytic
configurations, because both widely discussed and commonly overlooked decisions can lead to marked variation. </span><o:p></o:p></p>
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<span style="font-size:12.0pt;font-family:"Arial",sans-serif">Please join us!</span><o:p></o:p></p>
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<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:black;border:none windowtext 1.0pt;padding:0in">Videoconference via Zoom</span></b><b><span style="font-family:"Arial",sans-serif;color:black"> </span></b><o:p></o:p></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black;border:none windowtext 1.0pt;padding:0in">Register in advance here (it’s easy!)</span><span style="font-family:"Arial",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in">: </span><span style="font-family:"Arial",sans-serif;color:#212121"><a href="https://umassmed.zoom.us/meeting/register/v5Ikce2qrzkjF_dnGYL7_CeVQ_JqodcCrA" title="https://umassmed.zoom.us/meeting/register/v5Ikce2qrzkjF_dnGYL7_CeVQ_JqodcCrA"><span style="color:#954F72">https://umassmed.zoom.us/meeting/register/v5Ikce2qrzkjF_dnGYL7_CeVQ_JqodcCrA</span></a> </span><span style="font-family:"Arial",sans-serif;color:#201F1E"> </span><o:p></o:p></p>
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<p class="MsoNormal" style="margin-right:81.0pt;text-indent:.5in"><span style="font-family:"Arial",sans-serif;color:black;border:none windowtext 1.0pt;padding:0in">Once you’ve registered, you should receive a confirmation email containing information on how
to join the meeting. </span><o:p></o:p></p>
<p class="MsoNormal" style="margin-right:81.0pt;text-indent:.5in"><span style="font-family:"Arial",sans-serif;color:black;border:none windowtext 1.0pt;padding:0in">Any questions or problems, please contact Julie Bates</span><span style="font-family:"Arial",sans-serif;color:#201F1E;border:none windowtext 1.0pt;padding:0in"> at </span><span style="font-family:"Arial",sans-serif;color:#212121"><a href="mailto:julianna.bates@umassmed.edu" target="loopstyle_link" data-loopstyle="link" title="mailto:julianna.bates@umassmed.edu"><span style="color:#954F72">julianna.bates@umassmed.edu</span></a></span><o:p></o:p></p>
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<span style="font-size:12.0pt;font-family:"Arial",sans-serif">Welcome All!</span><o:p></o:p></p>
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<span style="font-size:12.0pt;font-family:"Arial",sans-serif">Julie</span><o:p></o:p></p>
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