NIH Pediatric MRI Data Repository News

NIH Pediatric MRI Data Repository - 5th Release

NDAR Administrator — Mon, 09 Jul 2012 1:04:30 GMT

The National Institutes of Health (NIH) are pleased to make available the 5th data release of the NIH MRI Study of Normal Brain Development to qualified researchers on April 26, 2012. New in this release are longitudinally-registered anatomic MRI data (images and derived volumetric measures), processed single-voxel MRS data which has been corrected for CSF voxel content, raw multi-voxel MRSI files, low resolution (3mm) diffusion tensor imaging (DTI) data, additional demographic measures, and revised biospecimen collection dates. Previous releases contained non-longitudinally registered anatomic MRI data (scans and derived volumes), cortical surface analysis data, age-specific brain atlases, raw and preliminary single-voxel MRS data uncorrected for CSF voxel content, and clinical/behavioral data for subjects aged 10 days to young adult. To learn about accessing this data, please visit http://pediatricmri.nih.gov.

NIH Pediatric MRI Data Repository - NEW release

Judith Rumsey — Wed, 30 Jun 2010 3:10:25 GMT

This is an announcement that a new data release is now available for distribution to approved users in the scientific community with active Data Use Certifications. This release includes longitudinal imaging and clinical/behavioral data for children, ages 7 days to young adult (both "Objective 1" and "Objective 2"). The imaging modalities included are anatomic MRI and MR spectroscopy.

Specifically, the latest additions to the repository include cortical surface analysis data for Objective1 (ages 4 ½ and older) and for a portion of Objective 2 (down to 2 years of age) for all timepoints, as well as age-specific brain atlases. Included as part of the cortical surface analysis data are surfaces in native space, transformation to stereotaxic space, gray and white surfaces, cortical thickness at each of 40,962 vertices per hemisphere, gyrification index, and surface mean
curvature. The MRI atlas templates include both symmetric and asymmetric atlases for the following overlapping age groups, generally corresponding to pubertal stages: 4.5 to 8.5 years(pre-pubertal), 7 to 11 years (pre- to early puberty), 5.5 to 13.5 years (pre- to mid-puberty), 10 to 14 years (early to advanced puberty), and 13 to 18.5 years (mid-puberty through post-puberty).

Please note, the Data Use Certifications are valid for one year, after which investigators who wish to remain active and those whose Data Use Certifications have expired must reapply and submit a short progress report. See www.NIH-PediatricMRI.org and click on the Data Access link. To gain access to the database, two forms--the SF 424 form and the Data Use Certification--must be completed, signed by your institution’s authorized signing official, and sent to the NIH by FAX.

If you have any questions, please send an email to pedsmri@mail.nih.gov

NIH Pediatric MRI Data Repository - 3rd release

Judith Rumsey — Thu, 10 Sep 2009 3:55:55 GMT

NIH Pediatric MRI Data Repository Announces Third Release of Data

This third release includes longitudinal anatomic MRI and MR spectroscopy data for ages 7 days through young adult.

The NIH Pediatric MRI Data Repository has released its third set of data from the NIH Pediatric Magnetic Resonance Imaging (MRI) Study of Normal Brain Development, an effort to establish a database of magnetic resonance imaging and correlated clinical/behavioral data reflecting healthy pediatric brain development as a resource for the scientific community. This third release includes longitudinal imaging and clinical/behavioral data for children ages 7 days to young adult. Included are anatomic MRI and MR spectroscopy data (both raw and processed), along with correlated data from physical neurological examinations, behavioral ratings, neuropsychological testing, structured psychiatric interviews, and hormonal measures from urine and saliva samples. All data has been anonymized to protect the confidentiality of the research participants.

The new data release is available for distribution to qualified researchers in the scientific community with approved applications, consisting of a data access request using standard form 424 (SF424) and a valid Data Use Certification.

Visit http://www.NIH-PediatricMRI.org or contact pedsmri@mail.nih.gov to learn more about data access.

The multisite study and resulting repository provide reliable data on a representative sample of healthy, typically-developing children as a basis for elucidating deviations in brain development associated with childhood disorders, as well as access to image processing tools. The study enrolled over 500 children, ranging from infancy to young adulthood, who were evaluated at multiple timepoints, ranging from three timepoints for the older subjects to ten timepoints for some of the youngest subjects. Data collection began in November 2001 and ended in August 2007. Data has been released in stages throughout the course of the study.
Future data release plans include the addition of cortical thickness measures and diffusion tensor imaging (DTI) data (raw and processed) and the connection of this resource with the National Database for Autism Research (http://ndar.nih.gov), allowing cross data comparisons between these two unique data repositories.

The Pediatric MRI Study of Normal Brain Development was sponsored by four NIH Institutes: the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute on Drug Abuse (NIDA), the National Institute of Mental Health (NIMH), and the National Institute of Neurological Disorders and Stroke (NINDS). Participating sites included Boston Children's Hospital (Principal Investigator [PI] Michael J. Rivkin), Children's Hospital Medical Center of Cincinnati (PI William S. Ball), Children's Hospital of Philadelphia (PI Dah--Jyuu Wang), Montreal Neurological Institute (PI Alan Evans), University of California at Los Angeles (PI James T. McCracken), University of Texas Health Science Center (PI Michael Brandt), Washington University (PIs Kelly Botteron and Robert McKinstry), and the NICHD—intramural program (PI Carlo Pierpaoli).

New URL - www.NIH-PediatricMRI.org

Dave Kennedy — Tue, 08 Apr 2008 1:31:49 GMT

Please be advised that the preferred URL for the project now is:

www.NIH-PediatricMRI.org

This will stay constant - plus easier to remember!

NIH MRI Study of Normal Brain Development - Data Release 2

David Kennedy — Mon, 07 Apr 2008 8:55:02 GMT

Originally Posted to NITRC Community: 2008-03-12 10:12

From the NIHpd-announce mailing list:

It has been announced that Release 2 of the data for the NIH MRI Study of Normal Brain Development is now available. This data release contains the first two time points (visits) of the Objective 1 data set (children aged 4-18).

If you don't have access to these data yet, you can request access at

http://www.bic.mni.mcgill.ca/nihpd/info/

Sincerely,

Alex Zijdenbos

Pediatric MRI Data Repository First Data Release

David Kennedy — Mon, 07 Apr 2008 8:53:25 GMT

Originally posted at NITRC Community 2007-06-13 13:38

The first public data release for the Pediatric MRI Data Repository established by the NIH MRI Study of Normal Brain Development is now available. This is a multisite, longitudinal study of over 500 typically-developing children, ages newborn to young adult, that collected correlated imaging and clinical/behavioral data as a resource for the scientific community. The first data release includes anatomic MRI and clinical/behavioral data for the first timepoint for ages 4 1/2 to 18 years; additional data will be released in stages. Biomedical and biobehavioral researchers who wish to apply for access should go to http://www.bic.mni.mcgill.ca/nihpd/info.