[Brains-users] FW: Brains2 Tissue Classification -- White Matter Disease

Hans Johnson hans-johnson at uiowa.edu
Wed Jun 1 10:36:04 PDT 2005


------ Forwarded Message
From: "Dean, David" <ddean at memory.ucsf.edu>
Date: Mon, 25 Apr 2005 15:18:54 -0700
To: Hans Johnson <hans-johnson at uiowa.edu>, Vincent Magnotta
<vincent-magnotta at uiowa.edu>
Cc: "Rosen, Howie" <hrosen at memory.ucsf.edu>
Subject: Brains2 Tissue Classification -- White Matter Disease

Hi Drs. Johnson and Magnotta,
We've been working with Brains2 for about 6 months now, and we've had a good
amount of success with performing the standard workup on over 200 of our
scans.  We're able to get whole tissue and segmented lobar volumes, and
we're now looking to do more ROI tracing and the surface data.  However, we
wanted to ask you about a particular problem that we have with the tissue
classification step.

Given that we are working with Alzheimer's and dementia patients, we have
found that many of our patients have a significant amount of white matter
disease, which results in the white matter being misclassified as grey
matter.  When I examine the standard workups that we've done, it appears
that about half of the scans have a significant amount of white matter being
misclassified in this way.

And so our first question is whether or not this is something that you deal
with at the IPL?  And if you do, how do you go about excluding or fixing
those scans with a noticable amount of white matter disease?
Thanks,
David

David L Dean
Brain Image Analysis Coordinator
UCSF Memory and Aging Center
350 Parnassus, Suite 706
San Francisco, CA 94143-1207
http://www.memory.ucsf.edu/

Phone: 415-502-0619
Fax: 415-476-0213
ddean at memory.ucsf.edu



------ End of Forwarded Message





More information about the Brains-users mailing list