[Brains-users] T1 and T2 voxel size

[Cherie Marvel]

Hi IPL Folks,
 
Some of us have been left behind and are continuing to work while
others are expanding their minds in Florence...
 
We are working out parameters to achieve a high resolution scan for T1
and T2 for measuring brain structures.  Our scanner is a Phillips 3T.  I
think we have a decent MPRAGE worked out, and the voxel size is .83 x
.88 x 1.00.  The best T2 we can acquire without artifact, however, has a
voxel size of 1 x 1 x 1.5.  We are acquiring in the sagittal plane
(because it conforms with parameters of our concurrent fMRI study).  
 
My question is whether the T1 and T2 images must be of the same voxel
size.  If not, how different can they "safely" be and still achieve
accurate measures?
 
I have noticed in past protocols that the two voxel sizes may be
slightly different (e.g., MR5).  However, it's unclear to me how BRAINS2
would handle registration, tissue classification, and volumetric
measurements if the two MR images have different voxel sizes.  
 
Any input on this would be greatly appreciated.  
 
thanks,
 
--cherie
 
 
Cherie L. Marvel, PhD
Research Associate
Johns Hopkins Medicine
Department of Neurology
Division of Cognitive Neuroscience
1620 McElderry St., Reed Hall E-2
Baltimore, MD 21205
Tel: (410) 502-4664
Fax: (410) 502-2189
www.jhu.edu/nimlab

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