[Camino-users] question re interpolated tractography

[Philip A Cook]

Hi Michael,

In the algorithms currently implemented, the curvature threshold is related to the slice thickness of the data (the z dimension). So if your slice thickness is 2mm, the curvature is evaluated every 2mm, approximately. If you are tracking with a step size of .2 mm, then your curvature will be tested once every 10 steps. With FACT, the displacement per step can vary according to how much of the voxel you traverse, so it is less precise but it should be approximately the same if you have isotropic voxels.


Phil

On Mar 13, 2012, at 1:27 PM, Michael Zeineh wrote:

> Hi all,
> 
> A question re interpolation on with tractography and curvature thresholds. Let us say voxel size is 2mm isotropic.
> 
> If interpolation is OFF, then the I assume the curvature is measured voxel to voxel along the course of the track, and if the curvature from one voxel to the next (separated by the step size of 2mm) exceeds the threshold, then the track is stopped.
> 
> If interpolation is ON (and the step size is the default of 0.2mm), then the same things happens, but across a much shorter distance (which means that the track is much less likely to curve anyways).
> 
> So a net effect of this is that for the same track, one obtained with interpolation on, and the other with interpolation off, the measured curvature will be different? So one should have a more strict threshold with interpolation on?
> 
> Or is my thought process totally off, and curvature is measured independently from the step size in some way ...
> 
> Thank you for any comments,
> 
> Michael Zeineh, M.D.-Ph.D.
> Assistant Professor, Dept of Radiology
> 300 Pasteur Drive, Room S-047
> Stanford, CA  94305-5105
> t:  650-721-1419
> c: 650-722-2235
> f:  650-498-5374
> mzeineh at stanford.edu
> 
> 
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