[Mrtrix-discussion] question about CSD

[Donald Tournier]

Hi Michael,

Yes, it should work with anisotropic voxels (although isotropic would
always be recommended). There is little point interpolating (at least
not using linear interpolation), since the tracking code performs
linear interpolation while tracking. In terms of bias, the
orientations are provided with respect to real (scanner) coordinates,
so do not depend on the voxel dimensions. There would however be a
bias when tracking WM structures oriented predominantly through-plane
versus in-plane, since the "effective resolution" would be higher in
the first case. This applies to all tracking methods though, not just
MRtrix (and is not a limitation of the CSD itself).

Hope that helps,

Donald.


2010/1/16 Michael Zeineh <mmzeineh at gmail.com>:
> Out of curiosity, will it work on anisotropic diffusion data (i.e.
> voxels are thicker along one axis)? If so, would there be any expected
> errors or biases? Would simple interpolation (somewhat) resolve those
> issues?
>
> Thank you,
> Michael
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-- 
Jacques-Donald Tournier (PhD)
Brain Research Institute, Melbourne, Australia
Tel: +61 (0)3 9496 4078