[Mrtrix-discussion] Tracking parameters for high resolution monkey data

[Thomas, Cibu (NIH/NICHD) [V]]

Hello
I am trying tractography on ex-vivo macaque brain high angular DW data acquired at a resolution of 250 microns isotropic.
I am using the following command to generate tracts in the whole brain
streamtrack SD_STREAM CSD8.mif -seed mask.mif -mask mask.mif cst_csd.tck -step 0.0375 -curvature 0.049 -grad grads.txt -number 3000000 -minlength 2 -cutoff 0.10

My question is, are there any recommendations regarding the optimal parameters to be used for tracking with the high res data that I have. Specifically, given the voxels size of the data, is the step size, curvature, number, minlength and cutoff appropriate? Is there an anatomically/empirically guided way to assign these parameters? I couldn't find any in the literature. What is a reasonable rule of thumb?

Thank you

Cibu Thomas