[Repronim-announcement] October ReproNim Webinar and Office Hours

Bates, Julianna (Julie) Julianna.Bates at umassmed.edu
Tue Oct 1 18:44:17 EDT 2024


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ReproNim: A Center for Neuroimaging Computation




ReproNim 'First Thursdays' Drop-In Office Hours  - Thursday, October 3, 2024

All are welcome to our ReproNim Office Hours Program! Do you have a reproducibility question, challenge, or problem?

Our next Drop-In Session will be Thursday, October 3, 2024, from 1-2pm ET, via Gathertown.

  *   G​athertown https://gather.town/app/ESJPNXX7CVirKett/nmind<https://t.co/uE0qveSTC5?amp=1>

-If you have any difficulty connecting, please email David Kennedy (david.kennedy at umassmed.edu<mailto:david.kennedy at umassmed.edu>) or Julie Bates (julianna.bates at umassmed.edu<mailto:julianna.bates at umassmed.edu>)
-If you sign in to Gathertown but don't see ReproNim folks, please look for 'ReproNim Dave'





ReproNim 'First Fridays' Webinar – Friday, October 4, at 2pm Eastern Time

Our special guest speaker this month is Mike Milham<https://childmind.org/bio/michael-p-milham-md-phd/>, who joins us from the Child Mind Institute, for a presentation on some of his very recent work (Nature Human Behavior, August 2024<https://www.nature.com/articles/s41562-024-01942-4>): "Moving beyond processing- and analysis-related variation in resting-state functional brain imaging." [See Abstract below]

Mike’s work spans brain development, child and adolescent psychiatry, and the advancement of neuroimaging data sharing initiatives and implementation of big data all in the service of understanding how functional & structural connectivity in brain may underlie mental illness. Among numerous leadership positions, he is the founding Director for the CMI Center for the Developing Brain, and Director of the Healthy Brain Network. He has pioneered innovative initiatives, including co-founding the 1000 Functional Connectomes Project, and that project’s International Neuroimaging Data-Sharing Initiative.

Abstract
When fields lack consensus standard methods and accessible ground truths, reproducibility can be more of an ideal than a reality. Such has been the case for functional neuroimaging, where there exists a sprawling space of tools and processing pipelines. We provide a critical evaluation of the impact of differences across five independently developed minimal preprocessing pipelines for functional magnetic resonance imaging. We show that, even when handling identical data, interpipeline agreement was only moderate, critically shedding light on a factor that limits cross-study reproducibility. We show that low interpipeline agreement can go unrecognized until the reliability of the underlying data is high, which is increasingly the case as the field progresses. Crucially we show that, when interpipeline agreement is compromised, so too is the consistency of insights from brain-wide association studies. We highlight the importance of comparing analytic configurations, because both widely discussed and commonly overlooked decisions can lead to marked variation.



Please join us!




Videoconference via Zoom
Register in advance here (it’s easy!): https://umassmed.zoom.us/meeting/register/v5Ikce2qrzkjF_dnGYL7_CeVQ_JqodcCrA

Once you’ve registered, you should receive a confirmation email containing information on how to join the meeting.
Any questions or problems, please contact Julie Bates at julianna.bates at umassmed.edu<mailto:julianna.bates at umassmed.edu>







Welcome All!



Julie








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