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sdm-help-list > Inquiry on Combining Task-State and Resting-State fMRI Data in Meta-Analysis
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Jan 22, 2024 02:01 PM | jingjing QIU - Guangzhou university of Chinese medicine
Inquiry on Combining Task-State and Resting-State fMRI Data in Meta-Analysis
We
are exploring altered brain function in depressed patients,
compared to normal subjects. We have attempted to combine
task-state and resting-state fMRI data for analysis. In our
literature review, We came across an article published in 2013 in
PLOS ONE, titled “Neural Correlates of Psychotherapy in Anxiety and
Depression: A Meta-Analysis.” We noticed that the author
successfully combined task-state and resting-state data in the
analysis. We'd like to know what the criteria are for harmonizing
the analyses. If it's all about whole-brain based studies of
patients versus normal subjects, can the task-state and
resting-state coordinates be analysed together? We are looking
forward to any guidance and advice you could provide. Thank you in
advance for your valuable time and the response you may
offer.
Mar 4, 2024 03:03 PM | Lydia Fortea - Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS)
RE: Inquiry on Combining Task-State and Resting-State fMRI Data in Meta-Analysis
Good afternoon,
It is not recommended to analyze tasks-based and resting fMRI together in one meta-analysis, as they measure different things. However, you could conduct each meta-analysis separately and then use the multimodal option to check the overlapped regions,
Best,
Lydia