Hello, 

I have a multishell diffusion protocol (see parameters below) and was curious if I can apply a DKI model to the data through DKE to obtain DKI metrics? Or, are the below parameters insufficient for DKI? 

Thank you in advance for your help!
Cristina

3T Siemens Prisma Scanner, 64-channel head coil
Multiband factor of 3, no GRAPPA, bipolar acquisition
Diffusion directions calculated using INRIA (Caruyer et al., 2013)
Six separate scans
12 directions, 2 B0s (A>>P), b= 500 s/mm2
12 directions, 2 B0s (P>>A), b= 500 s/mm2
29 directions, 3 B0s (A>>P), b=1500 s/mm2
29 directions, 3 B0s (P>>A), b=1500 s/mm2
64 directions, 4 B0s (A>>P), b=3000 s/mm2
64 directions, 4 B0s (A>>P), b=3000 s/mm2
Data was concatenated and run through topup and eddy

Hi Cristina,

The parameters you supplied are sufficient for DKI and DKE should work just fine with your dataset. However, DKE is now a legacy software that is no longer supported. Our lab has transitioned to a similar tool called PyDesigner, which we encourage all DKE users to consider using as well. It is a hands-off Python-based implementation of NYU's DESIGNER dMRI preprocessing pipeline designed to maximize signal-to-noise ratio. You can read about it further on the PyDesigner Github page here and in the PyDesigner documentation here.

Thank you very much, Kayti!