Network Modification (NeMo) Tool Lite
The NeMo Tool is the first that associates localized white matter (WM) lesions with
disruptions in gray matter connectivity as a step toward understanding the lesions’ functional
implications. A Tractogram Reference Set (TRS), i.e. collections of white matter fibers, is
constructed from 73 normal healthy individuals and coregistered to a common space (MNI). The
NeMo Tool uses the TRS to assess structural network disruption due to a particular WM lesion
mask on a region and network-wise level. This tool is an easy way for researchers and clinicians
to investigate changes in the structural brain network without having to perform tractography on
their own normal data or on diseased/injured brains where the results may not represent the
underlying physiology.
disruptions in gray matter connectivity as a step toward understanding the lesions’ functional
implications. A Tractogram Reference Set (TRS), i.e. collections of white matter fibers, is
constructed from 73 normal healthy individuals and coregistered to a common space (MNI). The
NeMo Tool uses the TRS to assess structural network disruption due to a particular WM lesion
mask on a region and network-wise level. This tool is an easy way for researchers and clinicians
to investigate changes in the structural brain network without having to perform tractography on
their own normal data or on diseased/injured brains where the results may not represent the
underlying physiology.
Specifications
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