sdm-help-list > How combine different rs-fMRI metrics for a coordinate-based meta-analysis
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Dec 4, 2024  09:12 AM | cmartin
How combine different rs-fMRI metrics for a coordinate-based meta-analysis

I plan to perform a coordinate-based meta-analysis by combining different rs-fMRI measures and I am interested to know what measures can be combined. Is it possible to combine peak coordinates derived from ALFF/fALFF, ReHo, ICA-DMN, and Functional connectivity measures (e.g., derived from voxel-based analysis or graph theory) in ES-SDM software? 

Feb 17, 2025  10:02 AM | Lydia Fortea - Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS)
RE: How combine different rs-fMRI metrics for a coordinate-based meta-analysis

Dear Cmartin, 


Combining different rs-fMRI measures in a meta-analysis is inappropriate, as this would assume they represent the same underlying construct, which they do not. Each measure reflects distinct aspects of brain function.


 


Best.


Lydia