Posted By: David Kennedy - Jun 25, 2008
Tool/Resource: NITRC Community
 
Request for Information (RFI): Emerging Capabilities for Non-Invasive Imaging of Brain Structure and Function (Neuroscience Blueprint)

Notice Number: NOT-AG-08-005

See http://grants.nih.gov/grants/guide/notic...

Information Requested:
Neuroimaging has proved to be a useful tool in neuroscience research and of great benefit in studying the human brain in healthy and diseased states. Non-invasive brain imaging offers a unique opportunity to peer into the inner workings of the brain to monitor normal and abnormal changes in structure and function, and to diagnose human brain disorders and monitor response to therapy. Studies on brain imaging are of interest to the NIH Neuroscience Blueprint. Imaging of brain can encompass multiple levels of analysis, e.g. from molecules to cell activity to neural connections, using multi-modality approaches with the ultimate goal of non-invasive imaging of human brain structure and function. The goal of this RFI is to identify brain imaging capabilities that are in the early phase of development, or do not yet exist but are on the horizon, which could significantly advance our understanding of human brain structure and function. Comments pertaining to desired new capabilities and innovative technologies for non-invasive human brain imaging, from molecular imaging to neural connectivity imaging, are encouraged. To assist in identifying scientific opportunities in new approaches to enhance and extend the capabilities of non-invasive human brain imaging, the participating NIH Blueprint Institutes and Centers request responses to the questions below:

1. What new imaging capabilities would most significantly advance our understanding of brain structure and function?
2. What emerging technologies are poised for rapid advancement or are on the horizon that could enhance non-invasive imaging of brain at various levels of analysis, e.g. from molecular to neural connectivity?
3. Are there emerging non-invasive brain imaging methods that would enable increased spatial and temporal resolution, and/or provide quantitative measures of brain structure and function?
4. Are there specific scientific impediments to research on non-invasive imaging of human brain structure and function, particularly at different levels of analysis? If so, what tools and resources are needed to overcome these impediments?

Responses:
Please send responses to wiseb@nia.nih.gov no later than August 1, 2008.

Inquiries:
Specific questions about this Notice may be directed to:

Bradley C. Wise, Ph.D.
Director, Fundamental Neuroscience Program
Division of Neuroscience
National Institute on Aging
7201 Wisconsin Avenue, Suite 350, MSC 9205
Bethesda, Maryland 20892-9205
Phone: 301-496-9350
Fax: 301-496-1494
Email: wiseb@nia.nih.gov
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