Dear all,

We are analysing ASL-data and our research question is, whether there is an association between a baseline value (one value per subject) and changes in ASL-signal (between 2 conditions, within one subject).
This means that every subject has one baseline value and two following ASL-scans (control vs. intervention) and we'd like to find out whether there's an association between these measures.
We used a 2-repeated measure design and compared the ASL scans in a paired t-test.

We wanted to ask, whether it is valid to look at the association between these measures within SPM in a paired t-test and if not, what the best way would be to do this.

Thanks a lot for your help,
Nathalie