Dear all, 

as I understood NiiStat assumes a score to decrease with lesion size. If I want to assess a score that increases with lesion size (i.e. NIHSS,EDSS) with VLSM, at your opinion is it valid to invert it (so to take the maximum possible score and subtract the true value from that, i.e. NIHSS=11, NIHSSinv=42-11= 31)? Is it even necessary or do I misunderstand the assumption of an inversly proportinal correlation?
Thanks, 
Best Regards
Matthias