We mainly support the linux binaries, but the Mac should work. The binaries are though not usual Mac-OS apps, but rather binaries that you need to call through the terminal, just the way one would use it on linux.

For that 
a) open Terminal
b) cd
c) set AUTOSEG_HOME environment variable to that directory:
export AUTOSEG_HOME=
d) ./AutoSeg -gui 

Best
Martin