sdm-help-list > RE: A question about the image result
Apr 17, 2018  11:04 AM | Joaquim Radua
RE: A question about the image result
Dear Jane,

I think that this may be an issue related to the use of random-effects models. Specifically, in the center of the cluster the estimated heterogeneity might be larger, and thus the z-value might be occasionally lower.

This is not a problem of SDM, but of random-effects meta-analysis, as you can check in R:
library(metafor)
rma(c(0,0,0,0,0,0,0,0,2,3),rep(1,10))
rma(c(0,0,0,0,0,0,0,0,3,3),rep(1,10)) # The arithmetic mean is larger but the estimate and z-value is lower

However, this is a minor problem as compared to the multiple advantages of using random-effects. See e.g. https://doi.org/10.3389/fnins.2017.00745

With the best wishes,

Joaquim

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TitleAuthorDate
Yangqian Shen Apr 12, 2018
RE: A question about the image result
Joaquim Radua Apr 17, 2018