Andrew,

Thank you for the suggestion, I will give this a read. Quick question - as I understand, there is more than one (non-trivial) way to encode a particular GLM using a design matrix/contrast. Is there anything specific to the way GLMs are implemented in the NBS software that restrict these parameters? Or should, in principle, any design matrix/contrast work for NBS as long as it is generally acceptable as defined by the booklet you shared, for example?

Best,

Paul