Dear Professor,

I have a question about how to perform a one-subject t-test in NBS / dNBS. I did find the previous discussion that is similar to this (https://www.nitrc.org/forum/message.php?...) but I don't think I have found the answer to how to set the design matrix.

My case is that I now have one condition and 37 participants' FC under it. I now want to look at the overall group connections under this condition that are significant. How should I set the design matrix? I want to assess if the mean is greater than 0, so I used one sample and tried the design matrix full of 1 and the contrast of [1]. But it always gives me min and max of 0.

(In addition, it seems that you cannot run one sample t-test in dNBS, am I correct?)

Any input is greatly appreciated. Thank you for your time and assistance.

Kind regards

Eric