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Notes:
This is an atlas set that can be used with ASHS software to perform
automatic segmentation.
This atlas set was constructed from MRI scans acquired in research
studies
conducted at the Penn Memory Center at the University of
Pennsylvania by David
A. Wolk, Paul A. Yushkevich and colleagues. The scans have been
segmented
manually by John Pluta with consultation from Song-Lin Ding (Allen
Brain
Institute).
Copyright (C) 2014 Paul Yushkevich, David Wolk, John Pluta,
Song-Lin Ding
The atlas contains segmented scans of 29 older adults, 14 meeting
the Peterson
criteria for amnestic mild cognitive impairment, and 15 controls.
Scans were
acquired at 3 Tesla. The T2-weighted scans are at 0.4x0.4x2.6mm3
resolution.
The manual segmentations by Pluta and Ding include several labels,
including
hippocampal subfields traced along the full length of the
hippocampus, and
extrahippocampal cortical structures (ERC/PRC/PHC).
A second file containing skull-stripped T1-weighted scans of the 29
atlas subjects
has been included for those who want to rerun ASHS training using
this dataset.
Any use in publication should cite Yushkevich PA, Pluta J, Wang H,
Ding SL, Xie L, Gertje E, Mancuso L, Kliot D, Das SR and Wolk DA
(2015). Automated volumetry and regional thickness analysis of
hippocampal subfields and medial temporal cortical structures in
mild cognitive impairment. Human brain mapping, 36(1), 258-287.
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