The Neurophysiological Biomarker Toolbox (NBT) is an open source Matlab toolbox for the computation and integration of neurophysiological biomarkers. NBT offers a pipeline from data storage to statistics including artefact rejection, signal visualization, biomarker computation, and statistical testing. NBT allows for easy implementation of new biomarkers, and incorporates an online wiki (http://www.nbtwiki.net/) that facilitates collaboration among NBT users including extensive help and tutorials.
NBT is specialized in analyzing EEG data, however it allows the processing of any kind of signal.
NBT can, e.g., be used to analyze ongoing oscillation between:

- Eyes-closed rest of subject populations (e.g., healthy subjects and patients, males vs. females, young vs. old, etc.).
- Two experimental condition (e.g., classical eyes-closed rest vs. meditation, or before vs. after consumption of a CNS-active substance (a drug, coffee, nicotine, alcohol, etc.).

More details can be found on http://www.nbtwiki.net/