Phenolyzer is a software aimed at phenotype/disease specific gene prioritization and gene network visualization. It can be used alone to prioritize genes genome-widely, or from user-specified genomic regions or genes. It can also be used to further prioritize genes after the variant annotation and filtering step from other tools, like ANNOVAR. Phenolyzer has both a command line version and a web version: see http://phenolyzer.wglab.org/ and https://github.com/WGLab/phenolyzer.