We have acquired resting state data on Siemens Skyra. Unfortunately, Prescan Normalization was turned off. This has resulted in moderate image intensity shading from the center out (dark in the center bright at the edges).  We have corrected our protocol but i am wondering what effect (if any) this shading will have on functional connectivity analysis.   I believe that the effect will be minimal since connectivity is determined by calculation the correlation of fMRI signal from voxel to voxel.  These seems reasonable to me but I am wondering what the experts think on this topic.

Thanks for your help in advance.

Bob