Hi CONN experts, 

I did an ROI-ROI gPPI analysis in CONN using a region in the parietal cortex as a seed and extracted connectivity values ROIs in the frontal and anterior cingulate cortices. I then did the same using the frontal ROI as a seed and extracting connectivity values for ROIs in parietal cortex. When I look at the results, they are quite different depending on it is a parietal seed to my frontal ROI vs a frontal seed to the same parietal ROI, however I would have expected that these results be the same. Would anybody be able to explain to me why connectivity would change between the exact same two regions depending on which one was selected as the seed?

Thanks,
Isabella