Dear Alfonso and other CONN users,

I have been comparing NBS results obtained using CONN and those obtained using the NBS toolbox (https://www.nitrc.org/projects/nbs/), and find the results with the two methods are somewhat different. I am using the same connectivity matrices and design matrices in both.

It seems that using the same initial threshold in both leads to a larger maximum network size in CONN (e.g. using p<0.05 one sided in CONN, and t<1.72 in NBS gives networks of 190 and 95 connections respectively). Also regardless of the edge level threshold, when calculating the p value for the network CONN seems to be less stringent than NBS (e.g. the 190 edge network has a p value of 0.0037 in CONN, while the 95 edge NBS one has a P value of 0.06. If one reduces the edge threshold to get a 190 edge network in NBS its p value is 0.09).

I was wondering does CONN use exactly the same methods as NBS, or is there a difference that explains this discrepancy?

Many thanks

Rob