help > RE: FSL preprocessing + conn
Nov 29, 2017  12:11 AM | Alfonso Nieto-Castanon - Boston University
RE: FSL preprocessing + conn
Hi Harris,

The preprocessing steps sound perfectly fine. You may simply:

a) import your fully-preprocessed MNI-space functional and structural data in the functional and structural tabs, respectively

b) if you have used mcflirt for motion correction enter the resulting .par files in CONN first-level covariates tab as a new covariate named 'realignment'

c) if you have used fsl_motion_outliers for outlier estimation enter the resulting regressor file also as a new first-level covariate now named 'scrubbing' (if you have not run any outlier estimation you may do so from CONN preprocessing tab -select 'functional outlier detection'- on your current data, which will automatically create the 'scrubbing' covariate for you)

After this, you may run any additional preprocessing steps directly from CONN (e.g. spatial smoothing), or you may skip that and proceed directly to the Denoising step. I would probably leave the default Denoising settings (alternatively you may choose to skip aCompCor -e.g. simply by removing the CSF and WhiteMatter ROIs from the 'confounds' list- if you find that somewhat redundant with the Retroicor step you have already run) and from that point on you may proceed normally. 

Hope this helps
Alfonso
Originally posted by Harrison Fisher:
Hello,

I have fMRI data preprocessed in FSL for GLM analysis using feat and I would also like to run connectivity analysis. Is there a way to generate and load in files that would normally be created by conn preprocessing to add the covariates that conn preprocessing automatically generates? (i.e. realignment, head motion etc.).

The bold images were preprocessed with the following:
RETROICOR
Slice Timing correction
Motion Correction
Topup correction

The bold images were then skull stripped with BET. 
I also have already run free surfer on all the mprage images and used bbregister, flirt and fnirt to align the structural to functional images and the standard (MNI152 1mm) to the structural. 

Any advice appreciated! 
Thanks
- Harris 
Napadow Lab
Martinos Center

Threaded View

TitleAuthorDate
Harrison Fisher Nov 28, 2017
RE: FSL preprocessing + conn
Alfonso Nieto-Castanon Nov 29, 2017
Giuseppe Pontillo Jun 17, 2020
Alfonso Nieto-Castanon Jun 18, 2020
Giuseppe Pontillo Jun 20, 2020
Giuseppe Pontillo Jun 21, 2020
Alfonso Nieto-Castanon Jun 22, 2020
stity Oct 13, 2020
Harrison Fisher Nov 30, 2017