help
help > RE: FSL preprocessing + conn
Nov 29, 2017 12:11 AM | Alfonso Nieto-Castanon - Boston University
RE: FSL preprocessing + conn
Hi Harris,
The preprocessing steps sound perfectly fine. You may simply:
a) import your fully-preprocessed MNI-space functional and structural data in the functional and structural tabs, respectively
b) if you have used mcflirt for motion correction enter the resulting .par files in CONN first-level covariates tab as a new covariate named 'realignment'
c) if you have used fsl_motion_outliers for outlier estimation enter the resulting regressor file also as a new first-level covariate now named 'scrubbing' (if you have not run any outlier estimation you may do so from CONN preprocessing tab -select 'functional outlier detection'- on your current data, which will automatically create the 'scrubbing' covariate for you)
After this, you may run any additional preprocessing steps directly from CONN (e.g. spatial smoothing), or you may skip that and proceed directly to the Denoising step. I would probably leave the default Denoising settings (alternatively you may choose to skip aCompCor -e.g. simply by removing the CSF and WhiteMatter ROIs from the 'confounds' list- if you find that somewhat redundant with the Retroicor step you have already run) and from that point on you may proceed normally.
Hope this helps
Alfonso
Originally posted by Harrison Fisher:
The preprocessing steps sound perfectly fine. You may simply:
a) import your fully-preprocessed MNI-space functional and structural data in the functional and structural tabs, respectively
b) if you have used mcflirt for motion correction enter the resulting .par files in CONN first-level covariates tab as a new covariate named 'realignment'
c) if you have used fsl_motion_outliers for outlier estimation enter the resulting regressor file also as a new first-level covariate now named 'scrubbing' (if you have not run any outlier estimation you may do so from CONN preprocessing tab -select 'functional outlier detection'- on your current data, which will automatically create the 'scrubbing' covariate for you)
After this, you may run any additional preprocessing steps directly from CONN (e.g. spatial smoothing), or you may skip that and proceed directly to the Denoising step. I would probably leave the default Denoising settings (alternatively you may choose to skip aCompCor -e.g. simply by removing the CSF and WhiteMatter ROIs from the 'confounds' list- if you find that somewhat redundant with the Retroicor step you have already run) and from that point on you may proceed normally.
Hope this helps
Alfonso
Originally posted by Harrison Fisher:
Hello,
I have fMRI data preprocessed in FSL for GLM analysis using feat and I would also like to run connectivity analysis. Is there a way to generate and load in files that would normally be created by conn preprocessing to add the covariates that conn preprocessing automatically generates? (i.e. realignment, head motion etc.).
The bold images were preprocessed with the following:
RETROICOR
Slice Timing correction
Motion Correction
Topup correction
The bold images were then skull stripped with BET.
I also have already run free surfer on all the mprage images and used bbregister, flirt and fnirt to align the structural to functional images and the standard (MNI152 1mm) to the structural.
Any advice appreciated!
Thanks
- Harris
Napadow Lab
Martinos Center
I have fMRI data preprocessed in FSL for GLM analysis using feat and I would also like to run connectivity analysis. Is there a way to generate and load in files that would normally be created by conn preprocessing to add the covariates that conn preprocessing automatically generates? (i.e. realignment, head motion etc.).
The bold images were preprocessed with the following:
RETROICOR
Slice Timing correction
Motion Correction
Topup correction
The bold images were then skull stripped with BET.
I also have already run free surfer on all the mprage images and used bbregister, flirt and fnirt to align the structural to functional images and the standard (MNI152 1mm) to the structural.
Any advice appreciated!
Thanks
- Harris
Napadow Lab
Martinos Center
Threaded View
Title | Author | Date |
---|---|---|
Harrison Fisher | Nov 28, 2017 | |
Alfonso Nieto-Castanon | Nov 29, 2017 | |
Giuseppe Pontillo | Jun 17, 2020 | |
Alfonso Nieto-Castanon | Jun 18, 2020 | |
Giuseppe Pontillo | Jun 20, 2020 | |
Giuseppe Pontillo | Jun 21, 2020 | |
Alfonso Nieto-Castanon | Jun 22, 2020 | |
stity | Oct 13, 2020 | |
Harrison Fisher | Nov 30, 2017 | |