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help > RE: How to denoise with global correlation
May 9, 2018 12:05 PM | Stephen L. - Coma Science Group, GIGA-Consciousness, Hospital & University of Liege
RE: How to denoise with global correlation
Dear Ines,
Unfortunately, I did not find any other way to regress out the effect of heterogenous scanners settings. For the moment, I dropped this kind of analysis in CONN as I got unreliable and meaningless results doing so, and I am rather doing separate analyses (one per center) that I then combine using a meta-review kind of analysis such as with the PVM software (see Costafreda, S. G. (2009). Pooling fMRI data: meta-analysis, mega-analysis and multi-center studies. Frontiers in neuroinformatics, 3, 33).
I am also looking into other approaches such as ICA regression and machine learning but they are all experimental, the most reliable way currently from what I have read so far seems to be the meta-analysis approach, as it assumes independence between the analyses, it is statistically perfectly fine to compare multicentric analyses this way (just like one can compare multiple studies results).
Unfortunately, I did not find any other way to regress out the effect of heterogenous scanners settings. For the moment, I dropped this kind of analysis in CONN as I got unreliable and meaningless results doing so, and I am rather doing separate analyses (one per center) that I then combine using a meta-review kind of analysis such as with the PVM software (see Costafreda, S. G. (2009). Pooling fMRI data: meta-analysis, mega-analysis and multi-center studies. Frontiers in neuroinformatics, 3, 33).
I am also looking into other approaches such as ICA regression and machine learning but they are all experimental, the most reliable way currently from what I have read so far seems to be the meta-analysis approach, as it assumes independence between the analyses, it is statistically perfectly fine to compare multicentric analyses this way (just like one can compare multiple studies results).
Threaded View
Title | Author | Date |
---|---|---|
Stephen L. | Jun 22, 2017 | |
Stephen L. | Nov 19, 2017 | |
Ines Del Cerro | May 8, 2018 | |
Stephen L. | May 9, 2018 | |
Ines Del Cerro | May 10, 2018 | |
Jeff Browndyke | Jun 28, 2017 | |
Stephen L. | Nov 16, 2017 | |