help > RE: Between & Within subjects design for Repeated Measures
Apr 3, 2019  12:04 AM | Andrew Zalesky
RE: Between & Within subjects design for Repeated Measures
Hi Danie,

I'm not quite sure of the between-subject effect that you have in mind, however, if you are interested in a grouping that remains consistent across the 4 time points (e.g. patients vs controls), you don't need a repeated measures design to test for this kind of between-group effect. For each subject, you could simply average the 4 connectivity matrices so that each subject is associated with a single matrix.

If you really do want to model each time point, this is also perfectly fine. You would include an explanatory variable for each subject to model the within-subject effect. Each of the explanatory variables would comprise fours 1's and 0's elsewhere. You would then include one additional explanatory variable to model the between-subject effect (e.g. patients vs controls). 

Andrew


Originally posted by Daniel Brennan:
Hello,
I have a repeated measures design, 19 subjects x 4 timepoints (1 covariate and 1 connectivity matrix for each timepoint). I believe I understand how to model the within-subjects effects at this stage; however, I'm unclear, given the 4 timepoints, how to model the between-subjects effects other than simply averaging the connectivity matrices + covariates to now have 19 datapoints each instead of 76. Is there a way to set up the design matrix so that between-subjects effects can be modeled?

Thank you,
Danie

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TitleAuthorDate
Daniel Brennan Apr 2, 2019
RE: Between & Within subjects design for Repeated Measures
Andrew Zalesky Apr 3, 2019
Daniel Brennan Apr 3, 2019
Andrew Zalesky Apr 3, 2019
Daniel Brennan Apr 4, 2019
Daniel Brennan Apr 3, 2019
Andrew Zalesky Apr 3, 2019