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help > RE: Result interpretation help!
Jun 11, 2021 10:06 PM | Alfonso Nieto-Castanon - Boston University
RE: Result interpretation help!
Dear Aishvarya
The beta/T stats represent the results from a two-sample t-test comparing cases>controls, so the signs of the beta/T values will be positive if connectivity is higher in cases compared to controls and negative otherwise (the stats are two-sided / two-tailed so the p-values will not change when evaluating controls>cases but the sign of the beta/T statistics will of course flip). The color of the lines, on the other hand, simply represents the sign of the connectivity on average in both cases and controls, so that will not change when testing cases>controls vs. controls>cases (in your case, for example, FP and Putamen show positive connectivity on average, with higher connectivity in controls compared to cases; in the example GUI shown in your attachment you may switch your contrast from 'Difference cases > controls' to 'Any effects (F-test)' if you want to see a bar display of the connectivity within cases and controls separately)
Hope this helps
Alfonso
Originally posted by Aishvarya Shri Rajasimman:
The beta/T stats represent the results from a two-sample t-test comparing cases>controls, so the signs of the beta/T values will be positive if connectivity is higher in cases compared to controls and negative otherwise (the stats are two-sided / two-tailed so the p-values will not change when evaluating controls>cases but the sign of the beta/T statistics will of course flip). The color of the lines, on the other hand, simply represents the sign of the connectivity on average in both cases and controls, so that will not change when testing cases>controls vs. controls>cases (in your case, for example, FP and Putamen show positive connectivity on average, with higher connectivity in controls compared to cases; in the example GUI shown in your attachment you may switch your contrast from 'Difference cases > controls' to 'Any effects (F-test)' if you want to see a bar display of the connectivity within cases and controls separately)
Hope this helps
Alfonso
Originally posted by Aishvarya Shri Rajasimman:
Dear all,
After analysis of resting state fmri between cases and controls in conn I have doubts regarding the interpretation.
After setting the contrast to [1 -1], i.e., cases> controls, for each selected seed there are few significant connections that are being displayed in either blue or red color (Attaching a picture below).
Please guide me,
here in the tabulation below (with contrast of [1 -1]),
1. Does the beta value and T score here represent the difference between cases and controls?
2. What does the plus or minus sign of T score indicate?
3. What is the significance of the color of the displayed connection ? (Because for a same seed, I could observe the color is red irrespective of setting cases> controls or controls>cases)
I would be grateful. Please guide me through.
Regards,
Aishvarya
After analysis of resting state fmri between cases and controls in conn I have doubts regarding the interpretation.
After setting the contrast to [1 -1], i.e., cases> controls, for each selected seed there are few significant connections that are being displayed in either blue or red color (Attaching a picture below).
Please guide me,
here in the tabulation below (with contrast of [1 -1]),
1. Does the beta value and T score here represent the difference between cases and controls?
2. What does the plus or minus sign of T score indicate?
3. What is the significance of the color of the displayed connection ? (Because for a same seed, I could observe the color is red irrespective of setting cases> controls or controls>cases)
I would be grateful. Please guide me through.
Regards,
Aishvarya
Threaded View
| Title | Author | Date |
|---|---|---|
| Aishvarya Shri Rajasimman | Jun 11, 2021 | |
| Aishvarya Shri Rajasimman | Jun 26, 2021 | |
| Alfonso Nieto-Castanon | Jun 28, 2021 | |
| sukhbinder Kumar | Jul 3, 2023 | |
| Alfonso Nieto-Castanon | Jun 11, 2021 | |
| Aishvarya Shri Rajasimman | Jun 12, 2021 | |