help > RE: Multiple ROIs & Multiple Comparisons Correction
Aug 19, 2022  06:08 AM | yoshi
RE: Multiple ROIs & Multiple Comparisons Correction
Originally posted by Alyssa Torske:
Dear Alfonso,

When uploading a ROI (as an atlas) which contains 4 parcellated subnucliei of said ROI/ seed region (e.g., left/right, medial/lateral insula) to conduct a SBC analysis, does one need to do additional multiple comparison corrections when looking at the functional connectivity changes in each subnuclei of the insula? e.i., should I be applying a Bonferroni correction and dividing the cluster threshold on second level as: FDR 0.05/4 ?
Or does CONN already take this into account somehow? I saw that for network based statistics, when there are multiple ROIs, this is done automatically, but I was not able to find any information as to whether this is also done for SBC analyses.
I look forward to hearing from you!
Kind regards,
Alyssa

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TitleAuthorDate
Alyssa Torske Aug 9, 2022
RE: Multiple ROIs & Multiple Comparisons Correction
yoshi Aug 19, 2022
Alfonso Nieto-Castanon Aug 29, 2022
Alyssa Torske Sep 1, 2022