Hello Alfonso,

I have a question regarding results being valid or not. My connectivity analysis in conn, for any contrast; A > B does not yield any results. However when I add covariates, this give me significant result. In another case the direction of the result changes. For example, after adding covariates the result that was shown for example as increased activation, now shows decreased activation.  

My question is are these resuts valid? Covariate needs to be checked only if original contrast A>B shows significant  results?  What about change in direction of activations when covarites are added? Are the results valid if it does not appear significant for the original contrast, but shows significance after covariates are addd?

Thank you