help > GM/WM/CSF ROIs in the surface-based analysis
Feb 28, 2025  01:02 AM | Michelle Cheng
GM/WM/CSF ROIs in the surface-based analysis

Dear CONN experts,


I have preprocessed a dataset using the "preprocessing pipeline for surface-based (in subject-space) using nonlinear coregistration." The structural images were brain.mgz files generated by FreeSurfer and aseg.mgz files were also incorporated. After the preprocessing, I noticed in the "Setup > ROIs" section that the gray matter, white matter, and CSF (c{1,2,3}_aseg.img respectively) were all pointed to "unsmoothed functional data (secondary dataset #1)." In the "Setup > Other imaging data" section, those unsmoothed functional data pointed to ww*.surf.nii, which I assume were functional data resampled on the cortical surface. Now my questions are:


1) Can I go ahead with this automatic configuration? Does CONN try to extract CSF signals from the cortical surface (!?) or automatically identify the corresponding volume-based functional data and extract the signal therein?


2) Or should I manually point the GM/WM/CSF ROIs to "subject-space functional data" also generated by the pipeline (ww*.nii with no "surf" in the file name) available in the Other imaging data section?


Thanks in advance for your help!


Sincerely,
Michelle

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TitleAuthorDate
GM/WM/CSF ROIs in the surface-based analysis
Michelle Cheng Feb 28, 2025
Alfonso Nieto-Castanon Mar 6, 2025
Michelle Cheng Mar 19, 2025