Hi Tamer,

It is perfectly fine/possible, although of course you will not be able to run volume-based group-level analyses since those analyses require some form of inter-subject coregistration at the level of voxels.

For example I would probably start with the pipeline named 'preprocessing pipeline for surface-based analyses (in subject-space) when FieldMaps are available' and then simply remove the last three functional steps ("functional Resampling of functional data within the cortical surface", "functional Label current functional files as "surface-space functional data"" and "functional Smoothing of surface-level functional data") and replace those with a simple "functional Smoothing (spatial convolution with Gaussian kernel)" step instead. That will fully preprocess your data while keeping it in subject-space (coregistered with each individual's anatomical file). 

Hope this helps

Alfonso

Originally posted by Tamer Gezici:

Hello,

Is there a recommended pipeline I can use for volume based analysis in subject space? Or is volume based subject space analysis not possible at all?

Thanks.

 

PS: Sorry for double posting, I was not aware that there was a special forum for CONN.