Dear Alfonso,

I 've posted a question regarding the  2 groups with 2-within subjects (pre, post intervention) model we used. We have three variables to be controlled. Is it correct to model [ 1 -1 0 0 0] for between-subjects and [1 -1] within-subjects contrast? The results indicate a significant functional connectivity between seed mPFC and inslua with F(2,30)=8.xxx in Conn results page. The reviewer questioned the first df and pointed out that it should be 1 (2-1)*(2-1)=1 instead of 2. The reviewer also questioned the calculation of the second df =30 with n=20. It seems that with n=20, df should be 20*2(pre, post) - 3covariates*2=34. Is it possible that Conn also regressed out other covariates that we aren't aware of? Any thoughts? Thank you.

--Lihong