[Mrtrix-discussion] FA vs. AFD/HMOA

[Dorian P.]

Thank you David. Yes, I was referring to morphometry (a large number of
researchers refer to VBA as VBM; don't know why they do it but I have
started to not mind the difference :).

Thank you for your poster, sounds very interesting.

One point for the comparison FA vs. AFD.


2014-05-06 21:26 GMT-04:00 David Raffelt <d.raffelt at brain.org.au>:

> Hi Dorian,
> Sounds like a good idea to me. You could do this in a tract-specific way
> (keeping in mind this previous discussion<http://www.nitrc.org/pipermail/mrtrix-discussion/2014-March/000926.html>on how to generate a tract-specific AFD measure).
>
> I'm guessing when you say VBM, you mean voxel-based *analysis *(VBA)? I
> know historically some papers<http://www.ncbi.nlm.nih.gov/pubmed/15907311>have used VBM to refer to voxel-wise FA analysis. However, personally I
> prefer to reserve VBM for studies investigating morphometry using T1
> segmentations, and use VBA for whole-brain voxel-wise studies in general.
>
> In terms of voxel-based analysis and correlations with AFD, we have a
> method to do this (see the attached ISMRM abstract from last year).
>
> Unfortunately this stats software (which we have renamed to
> connectivity-based fixel enhancement) won't be released in MRtrix for a few
> months. I'm currently still running experiments to identify optimal
> parameters and writing the paper.
>
> Hope this helps,
> Dave
>
>
>
>
>
>
> On 7 May 2014 04:07, Dorian P. <alb.net at gmail.com> wrote:
>
>> Dear all,
>>
>> I am attempting to compare FA and AFD (or HMOA) for their correlation
>> with a third behavioral measure. The idea is to check whether the new
>> measures have a better correlation with cognitive performance than the
>> traditional FA. I cannot come up with a flow in this logic. I wanted to ask
>> you opinion whether this comparison may or may not be appropriate. My
>> intuition is that AFD (or HMOA) may be an excellent replacement of FA, of
>> course not in VBM analyses, but in tract specific investigations. Am I
>> correct with this?
>>
>> Thank you.
>> Dorian
>> TJU
>>
>>
>>
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>>
>
>
> --
> *David Raffelt (PhD)*
> Post Doctoral Fellow
>
> The Florey Institute of Neuroscience and Mental Health
> Melbourne Brain Centre - Austin Campus
> 245 Burgundy Street
> Heidelberg Vic 3084
> Ph: +61 3 9035 7024
> www.florey.edu.au
>
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