PubMed Mentions

The links below are to publications on PubMed referring to PPMI. This list is gathered weekly from PubMed automatically.

Publication/References
Why shared data should not be acknowledged on the author byline. Description: Rohlfing, T, et al. Why shared data should not be acknowledged on the author byline. ''Neuroimage''. 2012 Feb 15; '''59''' (4):4189-95
A computational neurodegenerative disease progression score: method and results with the Alzheimer's disease Neuroimaging Initiative cohort. Description: Jedynak, Bruno M, et al. A computational neurodegenerative disease progression score: method and results with the Alzheimer's disease Neuroimaging Initiative cohort. ''Neuroimage''. 2012 Nov 15; '''63''' (3):1478-86
Biomarkers in Parkinson's disease (recent update). Description: Sharma, Sushil, et al. Biomarkers in Parkinson's disease (recent update). ''Neurochem Int''. 2013 Sep; '''63''' (3):201-29
Clinical comparison of 99mTc exametazime and 123I Ioflupane SPECT in patients with chronic mild traumatic brain injury. Description: Newberg, Andrew B, et al. Clinical comparison of 99mTc exametazime and 123I Ioflupane SPECT in patients with chronic mild traumatic brain injury. ''PLoS One''. 2014; '''9''' (1):e87009
High-throughput neuroimaging-genetics computational infrastructure. Description: Dinov, Ivo D, et al. High-throughput neuroimaging-genetics computational infrastructure. ''Front Neuroinform''. 2014; '''8''': 41
Large-scale resting state network correlates of cognitive impairment in Parkinson's disease and related dopaminergic deficits. Description: Lebedev, Alexander V, et al. Large-scale resting state network correlates of cognitive impairment in Parkinson's disease and related dopaminergic deficits. ''Front Syst Neurosci''. 2014; '''8''': 45
Blood Biomarkers Associated with Cognitive Decline in Early Stage and Drug-Naive Parkinson's Disease Patients. Description: Santiago, Jose A, et al. Blood Biomarkers Associated with Cognitive Decline in Early Stage and Drug-Naive Parkinson's Disease Patients. ''PLoS One''. 2015; '''10''' (11):e0142582
Decrease in plasma levels of alpha-synuclein is evident in patients with Parkinson's disease after elimination of heterophilic antibody interference. Description: Ishii, Ryotaro, et al. Decrease in plasma levels of alpha-synuclein is evident in patients with Parkinson's disease after elimination of heterophilic antibody interference. ''PLoS One''. 2015; '''10''' (4):e0123162
Morphological alterations in the caudate, putamen, pallidum, and thalamus in Parkinson's disease. Description: Garg, Amanmeet, et al. Morphological alterations in the caudate, putamen, pallidum, and thalamus in Parkinson's disease. ''Front Neurosci''. 2015; '''9''': 101
Sharing big biomedical data. Description: Toga, Arthur W, et al. Sharing big biomedical data. ''J Big Data''. 2015; '''2''':
Increased free water in the substantia nigra of Parkinson's disease: a single-site and multi-site study. Description: Ofori, Edward, et al. Increased free water in the substantia nigra of Parkinson's disease: a single-site and multi-site study. ''Neurobiol Aging''. 2015 Feb; '''36''' (2):1097-104
Planning for selective amygdalohippocampectomy involving less neuronal fiber damage based on brain connectivity using tractography. Description: Lee, Seung-Hak, et al. Planning for selective amygdalohippocampectomy involving less neuronal fiber damage based on brain connectivity using tractography. ''Neural Regen Res''. 2015 Jul; '''10''' (7):1107-12
Network structure of brain atrophy in de novo Parkinson's disease. Description: Zeighami, Yashar, et al. Network structure of brain atrophy in de novo Parkinson's disease. ''Elife''. 2015 Sep 7; '''4''':
CSF Biomarkers and Its Associations with 18F-AV133 Cerebral VMAT2 Binding in Parkinson's Disease-A Preliminary Report. Description: Gao, Rui, et al. CSF Biomarkers and Its Associations with 18F-AV133 Cerebral VMAT2 Binding in Parkinson's Disease-A Preliminary Report. ''PLoS One''. 2016; '''11''' (10):e0164762
Fatigue in Parkinson's disease: report from a mutidisciplinary symposium. Description: Friedman, Joseph H, et al. Fatigue in Parkinson's disease: report from a mutidisciplinary symposium. ''NPJ Parkinsons Dis''. 2016; '''2''':
Ipsilateral deficits of dopaminergic neurotransmission in Parkinson's disease. Description: Kaasinen, Valtteri. Ipsilateral deficits of dopaminergic neurotransmission in Parkinson's disease. ''Ann Clin Transl Neurol''. 2016 Jan; '''3''' (1):21-6
MGH-USC Human Connectome Project datasets with ultra-high b-value diffusion MRI. Description: Fan, Qiuyun, et al. MGH-USC Human Connectome Project datasets with ultra-high b-value diffusion MRI. ''Neuroimage''. 2016 Jan 1; '''124''' (Pt B):1108-1114
Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations. Description: Dinov, Ivo D, et al. Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations. ''PLoS One''. 2016; '''11''' (8):e0157077
Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging Study. Description: Zhang, Yu, et al. Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging Study. ''PLoS One''. 2016; '''11''' (10):e0165540
Structural connectivity profile of scans without evidence of dopaminergic deficit (SWEDD) patients compared to normal controls and Parkinson's disease patients. Description: Kim, Mansu, et al. Structural connectivity profile of scans without evidence of dopaminergic deficit (SWEDD) patients compared to normal controls and Parkinson's disease patients. ''Springerplus''. 2016; '''5''' (1):1421
Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression. Description: Davis, Albert A, et al. Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression. ''Neurobiol Aging''. 2016 Jan; '''37''': 209.e1-209.e7
White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration. Description: Kandel, Benjamin M, et al. White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration. ''Alzheimers Dement (Amst)''. 2016; '''4''': 18-27
Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants. Description: Nuytemans, Karen, et al. Overlap between Parkinson disease and Alzheimer disease in ABCA7 functional variants. ''Neurol Genet''. 2016 Feb; '''2''' (1):e44
Resting-state functional connectivity of the striatum in early-stage Parkinson's disease: Cognitive decline and motor symptomatology. Description: Manza, Peter, et al. Resting-state functional connectivity of the striatum in early-stage Parkinson's disease: Cognitive decline and motor symptomatology. ''Hum Brain Mapp''. 2016 Feb; '''37''' (2):648-62
Cerebrospinal Fluid Amyloid beta1-42, Tau, and Alpha-Synuclein Predict the Heterogeneous Progression of Cognitive Dysfunction in Parkinson's Disease. Description: Kang, Ju-Hee. Cerebrospinal Fluid Amyloid beta1-42, Tau, and Alpha-Synuclein Predict the Heterogeneous Progression of Cognitive Dysfunction in Parkinson's Disease. ''J Mov Disord''. 2016 May; '''9''' (2):89-96
Linear and Curvilinear Trajectories of Cortical Loss with Advancing Age and Disease Duration in Parkinson's Disease. Description: Claassen, Daniel O, et al. Linear and Curvilinear Trajectories of Cortical Loss with Advancing Age and Disease Duration in Parkinson's Disease. ''Aging Dis''. 2016 May; '''7''' (3):220-9
Structural Brain Alterations Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease. Description: Boucetta, Soufiane, et al. Structural Brain Alterations Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease. ''Sci Rep''. 2016 Jun 1; '''6''': 26782
The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort. Description: Kang, Un Jung, et al. The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort. ''Mov Disord''. 2016 Jun; '''31''' (6):924-32
Predictors of time to initiation of symptomatic therapy in early Parkinson's disease. Description: Simuni, Tanya, et al. Predictors of time to initiation of symptomatic therapy in early Parkinson's disease. ''Ann Clin Transl Neurol''. 2016 Jul; '''3''' (7):482-94
Normative data for subcortical regional volumes over the lifetime of the adult human brain. Description: Potvin, Olivier, et al. Normative data for subcortical regional volumes over the lifetime of the adult human brain. ''Neuroimage''. 2016 Aug 15; '''137''': 9-20
Integrative transcriptomic meta-analysis of Parkinson's disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson's disease. Description: Santiago, Jose A, et al. Integrative transcriptomic meta-analysis of Parkinson's disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson's disease. ''Sci Rep''. 2016 Sep 29; '''6''': 34579
Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease. Description: Podlesniy, Petar, et al. Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease. ''Neurobiol Dis''. 2016 Oct; '''94''': 10-7
White matter microstructural characteristics in newly diagnosed Parkinson's disease: An unbiased whole-brain study. Description: Wen, Ming-Ching, et al. White matter microstructural characteristics in newly diagnosed Parkinson's disease: An unbiased whole-brain study. ''Sci Rep''. 2016 Oct 20; '''6''': 35601
Alterations in striato-thalamo-pallidal intrinsic functional connectivity as a prodrome of Parkinson's disease. Description: Dayan, Eran, et al. Alterations in striato-thalamo-pallidal intrinsic functional connectivity as a prodrome of Parkinson's disease. ''Neuroimage Clin''. 2017; '''16''': 313-318
A test-retest study on Parkinson's PPMI dataset yields statistically significant white matter fascicles. Description: Cousineau, Martin, et al. A test-retest study on Parkinson's PPMI dataset yields statistically significant white matter fascicles. ''Neuroimage Clin''. 2017; '''16''': 222-233
BRAPH: A graph theory software for the analysis of brain connectivity. Description: Mijalkov, Mite, et al. BRAPH: A graph theory software for the analysis of brain connectivity. ''PLoS One''. 2017; '''12''' (8):e0178798
Comparison of Cortical and Subcortical Measurements in Normal Older Adults across Databases and Software Packages. Description: Rane, Swati, et al. Comparison of Cortical and Subcortical Measurements in Normal Older Adults across Databases and Software Packages. ''J Alzheimers Dis Rep''. 2017; '''1''' (1):59-70
Distinct Role of Striatal Functional Connectivity and Dopaminergic Loss in Parkinson's Symptoms. Description: Dukart, Juergen, et al. Distinct Role of Striatal Functional Connectivity and Dopaminergic Loss in Parkinson's Symptoms. ''Front Aging Neurosci''. 2017; '''9''': 151
Exploring the reproducibility of functional connectivity alterations in Parkinson's disease. Description: Badea, Liviu, et al. Exploring the reproducibility of functional connectivity alterations in Parkinson's disease. ''PLoS One''. 2017; '''12''' (11):e0188196
Functional Brain Imaging Synthesis Based on Image Decomposition and Kernel Modeling: Application to Neurodegenerative Diseases. Description: Martinez-Murcia, Francisco J, et al. Functional Brain Imaging Synthesis Based on Image Decomposition and Kernel Modeling: Application to Neurodegenerative Diseases. ''Front Neuroinform''. 2017; '''11''': 65
Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease. Description: Caspell-Garcia, Chelsea, et al. Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease. ''PLoS One''. 2017; '''12''' (5):e0175674
Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features. Description: Iyappan, Anandhi, et al. Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features. ''J Alzheimers Dis''. 2017; '''59''' (4):1153-1169
Refining diagnosis of Parkinson's disease with deep learning-based interpretation of dopamine transporter imaging. Description: Choi, Hongyoon, et al. Refining diagnosis of Parkinson's disease with deep learning-based interpretation of dopamine transporter imaging. ''Neuroimage Clin''. 2017; '''16''': 586-594
Serum IGF-1 is associated with cognitive functions in early, drug-naive Parkinson's disease. Description: Picillo, Marina, et al. Serum IGF-1 is associated with cognitive functions in early, drug-naive Parkinson's disease. ''PLoS One''. 2017; '''12''' (10):e0186508
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Description: Jansen, Iris E, et al. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. ''Genome Biol''. 2017 Jan 30; '''18''' (1):22
Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity. Description: Webb, Joseph, et al. Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity. ''Neurobiol Aging''. 2017 Feb; '''50''': 39-46
Probabilistic conversion of neurosurgical DBS electrode coordinates into MNI space. Description: Horn, Andreas, et al. Probabilistic conversion of neurosurgical DBS electrode coordinates into MNI space. ''Neuroimage''. 2017 Apr 15; '''150''': 395-404
Imaging genetics approach to Parkinson's disease and its correlation with clinical score. Description: Kim, Mansu, et al. Imaging genetics approach to Parkinson's disease and its correlation with clinical score. ''Sci Rep''. 2017 Apr 21; '''7''': 46700
Limbic grey matter changes in early Parkinson's disease. Description: Li, Xingfeng, et al. Limbic grey matter changes in early Parkinson's disease. ''Hum Brain Mapp''. 2017 Jul; '''38''' (7):3566-3578
A user's guide for alpha-synuclein biomarker studies in biological fluids: Perianalytical considerations. Description: Mollenhauer, Brit, et al. A user's guide for alpha-synuclein biomarker studies in biological fluids: Perianalytical considerations. ''Mov Disord''. 2017 Aug; '''32''' (8):1117-1130
Freesurfer cortical normative data for adults using Desikan-Killiany-Tourville and ex vivo protocols. Description: Potvin, Olivier, et al. Freesurfer cortical normative data for adults using Desikan-Killiany-Tourville and ex vivo protocols. ''Neuroimage''. 2017 Aug 1; '''156''': 43-64
Normative morphometric data for cerebral cortical areas over the lifetime of the adult human brain. Description: Potvin, Olivier, et al. Normative morphometric data for cerebral cortical areas over the lifetime of the adult human brain. ''Neuroimage''. 2017 Aug 1; '''156''': 315-339
Progression marker of Parkinson's disease: a 4-year multi-site imaging study. Description: Burciu, Roxana G, et al. Progression marker of Parkinson's disease: a 4-year multi-site imaging study. ''Brain''. 2017 Aug 1; '''140''' (8):2183-2192
Microstructural network alterations of olfactory dysfunction in newly diagnosed Parkinson's disease. Description: Wen, Ming-Ching, et al. Microstructural network alterations of olfactory dysfunction in newly diagnosed Parkinson's disease. ''Sci Rep''. 2017 Oct 2; '''7''' (1):12559
Correlation of Plasma EGF with Striatal Dopamine Transporter Availability in Healthy Subjects. Description: Pak, Kyoungjune, et al. Correlation of Plasma EGF with Striatal Dopamine Transporter Availability in Healthy Subjects. ''Sci Rep''. 2017 Oct 16; '''7''' (1):13261
Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls. Description: Mollenhauer, Brit, et al. Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls. ''Neurology''. 2017 Nov 7; '''89''' (19):1959-1969
Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. Description: Ibanez, Laura, et al. Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. ''BMC Neurol''. 2017 Nov 15; '''17''' (1):198
Comparison of machine learning and semi-quantification algorithms for (I123)FP-CIT classification: the beginning of the end for semi-quantification? Description: Taylor, Jonathan Christopher, et al. Comparison of machine learning and semi-quantification algorithms for (I123)FP-CIT classification: the beginning of the end for semi-quantification? ''EJNMMI Phys''. 2017 Nov 29; '''4''' (1):29
Abnormal Spontaneous Brain Activity in Early Parkinson's Disease With Mild Cognitive Impairment: A Resting-State fMRI Study. Description: Wang, Zhijiang, et al. Abnormal Spontaneous Brain Activity in Early Parkinson's Disease With Mild Cognitive Impairment: A Resting-State fMRI Study. ''Front Physiol''. 2018; '''9''': 1093
Advances in functional magnetic resonance imaging data analysis methods using Empirical Mode Decomposition to investigate temporal changes in early Parkinson's disease. Description: Cordes, Dietmar, et al. Advances in functional magnetic resonance imaging data analysis methods using Empirical Mode Decomposition to investigate temporal changes in early Parkinson's disease. ''Alzheimers Dement (N Y)''. 2018; '''4''': 372-386
Amnestic mild cognitive impairment individuals with dissimilar pathologic origins show common regional vulnerability in the default mode network. Description: Rane, Swati, et al. Amnestic mild cognitive impairment individuals with dissimilar pathologic origins show common regional vulnerability in the default mode network. ''Alzheimers Dement (Amst)''. 2018; '''10''': 717-725
Antibody biomarker for de novo Parkinson disease: attempted validation. Description: Feng, Na, et al. Antibody biomarker for de novo Parkinson disease: attempted validation. ''NPJ Parkinsons Dis''. 2018; '''4''': 28
Association Between Peripheral Inflammation and DATSCAN Data of the Striatal Nuclei in Different Motor Subtypes of Parkinson Disease. Description: Sanjari Moghaddam, Hossein, et al. Association Between Peripheral Inflammation and DATSCAN Data of the Striatal Nuclei in Different Motor Subtypes of Parkinson Disease. ''Front Neurol''. 2018; '''9''': 234
Autonomic dysfunction and white matter microstructural changes in drug-naive patients with Parkinson's disease. Description: Ashraf-Ganjouei, Amir, et al. Autonomic dysfunction and white matter microstructural changes in drug-naive patients with Parkinson's disease. ''PeerJ''. 2018; '''6''': e5539
Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort. Description: Simuni, Tanya, et al. Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: the PPMI cohort. ''J Neurol Neurosurg Psychiatry''. 2018 Jan; '''89''' (1):78-88
Brain tissue pulsatility is related to clinical features of Parkinson's disease. Description: Shirzadi, Zahra, et al. Brain tissue pulsatility is related to clinical features of Parkinson's disease. ''Neuroimage Clin''. 2018; '''20''': 222-227
Cognition among individuals along a spectrum of increased risk for Parkinson's disease. Description: Chahine, Lana M, et al. Cognition among individuals along a spectrum of increased risk for Parkinson's disease. ''PLoS One''. 2018; '''13''' (8):e0201964
Cognitive Profiles and Hub Vulnerability in Parkinson's Disease. Description: Lin, Sue-Jin, et al. Cognitive Profiles and Hub Vulnerability in Parkinson's Disease. ''Front Neurol''. 2018; '''9''': 482
Combining clinical and biofluid markers for early Parkinson's disease detection. Description: Yu, Zhenwei, et al. Combining clinical and biofluid markers for early Parkinson's disease detection. ''Ann Clin Transl Neurol''. 2018 Jan; '''5''' (1):109-114
CSF Abeta1-42 level is associated with cognitive decline in early Parkinson's disease with rapid eye movement sleep behavior disorder. Description: Ba, Maowen, et al. CSF Abeta1-42 level is associated with cognitive decline in early Parkinson's disease with rapid eye movement sleep behavior disorder. ''Transl Neurodegener''. 2018; '''7''': 22
Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis. Description: Conrado, Daniela J, et al. Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis. ''Clin Transl Sci''. 2018 Jan; '''11''' (1):63-70
Early Gray Matter Volume Loss in MAPT H1H1 de Novo PD Patients: A Possible Association With Cognitive Decline. Description: Sampedro, Frederic, et al. Early Gray Matter Volume Loss in MAPT H1H1 de Novo PD Patients: A Possible Association With Cognitive Decline. ''Front Neurol''. 2018; '''9''': 394
In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease. Description: Ray, Nicola J, et al. In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease. ''Brain''. 2018 Jan 1; '''141''' (1):165-176
Joint regression and classification via relational regularization for Parkinson's disease diagnosis. Description: Lei, Haijun, et al. Joint regression and classification via relational regularization for Parkinson's disease diagnosis. ''Technol Health Care''. 2018; '''26''' (S1):19-30
Longitudinal Alterations of Alpha-Synuclein, Amyloid Beta, Total, and Phosphorylated Tau in Cerebrospinal Fluid and Correlations Between Their Changes in Parkinson's Disease. Description: Dolatshahi, Mahsa, et al. Longitudinal Alterations of Alpha-Synuclein, Amyloid Beta, Total, and Phosphorylated Tau in Cerebrospinal Fluid and Correlations Between Their Changes in Parkinson's Disease. ''Front Neurol''. 2018; '''9''': 560
Longitudinal Connectomes as a Candidate Progression Marker for Prodromal Parkinson's Disease. Description: Pena-Nogales, Oscar, et al. Longitudinal Connectomes as a Candidate Progression Marker for Prodromal Parkinson's Disease. ''Front Neurosci''. 2018; '''12''': 967
Microstructural Changes in Patients With Parkinson's Disease Comorbid With REM Sleep Behaviour Disorder and Depressive Symptoms. Description: Ghazi Sherbaf, Farzaneh, et al. Microstructural Changes in Patients With Parkinson's Disease Comorbid With REM Sleep Behaviour Disorder and Depressive Symptoms. ''Front Neurol''. 2018; '''9''': 441
NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson's disease. Description: von Herrmann, Katharine M, et al. NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson's disease. ''NPJ Parkinsons Dis''. 2018; '''4''': 24
Patterns of grey matter loss associated with motor subscores in early Parkinson's disease. Description: Li, Xingfeng, et al. Patterns of grey matter loss associated with motor subscores in early Parkinson's disease. ''Neuroimage Clin''. 2018; '''17''': 498-504
Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease. Description: Ibanez, Laura, et al. Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease. ''Front Neurosci''. 2018; '''12''': 230
Progressive Decline in Gray and White Matter Integrity in de novo Parkinson's Disease: An Analysis of Longitudinal Parkinson Progression Markers Initiative Diffusion Tensor Imaging Data. Description: Taylor, Kirsten I, et al. Progressive Decline in Gray and White Matter Integrity in de novo Parkinson's Disease: An Analysis of Longitudinal Parkinson Progression Markers Initiative Diffusion Tensor Imaging Data. ''Front Aging Neurosci''. 2018; '''10''': 318
Risk factors of levodopa-induced dyskinesia in Parkinson's disease: results from the PPMI cohort. Description: Eusebi, Paolo, et al. Risk factors of levodopa-induced dyskinesia in Parkinson's disease: results from the PPMI cohort. ''NPJ Parkinsons Dis''. 2018; '''4''': 33
Robust Ensemble Classification Methodology for I123-Ioflupane SPECT Images and Multiple Heterogeneous Biomarkers in the Diagnosis of Parkinson's Disease. Description: Castillo-Barnes, Diego, et al. Robust Ensemble Classification Methodology for I123-Ioflupane SPECT Images and Multiple Heterogeneous Biomarkers in the Diagnosis of Parkinson's Disease. ''Front Neuroinform''. 2018; '''12''': 53
Serial I-123-FP-CIT SPECT Image Findings of Parkinson's Disease Patients With Levodopa-Induced Dyskinesia. Description: Jeong, Eun Hye, et al. Serial I-123-FP-CIT SPECT Image Findings of Parkinson's Disease Patients With Levodopa-Induced Dyskinesia. ''Front Neurol''. 2018; '''9''': 1133
Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure. Description: Ghazi Sherbaf, Farzaneh, et al. Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure. ''Front Endocrinol (Lausanne)''. 2018; '''9''': 608
Sparse feature learning for multi-class Parkinson's disease classification. Description: Lei, Haijun, et al. Sparse feature learning for multi-class Parkinson's disease classification. ''Technol Health Care''. 2018; '''26''' (S1):193-203
Structural Brain Network Alteration and its Correlation With Structural Impairments in Patients With Depression in de novo and Drug-Naive Parkinson's Disease. Description: Gou, Lubin, et al. Structural Brain Network Alteration and its Correlation With Structural Impairments in Patients With Depression in de novo and Drug-Naive Parkinson's Disease. ''Front Neurol''. 2018; '''9''': 608
Testing the Protein Propagation Hypothesis of Parkinson Disease. Description: Dagher, Alain, et al. Testing the Protein Propagation Hypothesis of Parkinson Disease. ''J Exp Neurosci''. 2018; '''12''': 1179069518786715
White matter hyperintensities are linked to future cognitive decline in de novo Parkinson's disease patients. Description: Dadar, Mahsa, et al. White matter hyperintensities are linked to future cognitive decline in de novo Parkinson's disease patients. ''Neuroimage Clin''. 2018; '''20''': 892-900
White Matter Tract Alterations in Drug-Naive Parkinson's Disease Patients With Impulse Control Disorders. Description: Mojtahed Zadeh, Mahtab, et al. White Matter Tract Alterations in Drug-Naive Parkinson's Disease Patients With Impulse Control Disorders. ''Front Neurol''. 2018; '''9''': 163
Deep gray matter volume loss drives disability worsening in multiple sclerosis. Description: Eshaghi, Arman, et al. Deep gray matter volume loss drives disability worsening in multiple sclerosis. ''Ann Neurol''. 2018 Feb; '''83''' (2):210-222
Risk variants of the alpha-synuclein locus and REM sleep behavior disorder in Parkinson's disease: a genetic association study. Description: Bjornara, Kari Anne, et al. Risk variants of the alpha-synuclein locus and REM sleep behavior disorder in Parkinson's disease: a genetic association study. ''BMC Neurol''. 2018 Feb 21; '''18''' (1):20
PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions. Description: Tsai, Pei-I, et al. PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions. ''Mol Cell''. 2018 Mar 1; '''69''' (5):744-756.e6
Cerebral blood flow predicts differential neurotransmitter activity. Description: Dukart, Juergen, et al. Cerebral blood flow predicts differential neurotransmitter activity. ''Sci Rep''. 2018 Mar 6; '''8''' (1):4074
The Effect of Obesity on the Availabilities of Dopamine and Serotonin Transporters. Description: Nam, Su Bong, et al. The Effect of Obesity on the Availabilities of Dopamine and Serotonin Transporters. ''Sci Rep''. 2018 Mar 21; '''8''' (1):4924
Excessive daytime sleepiness may be associated with caudate denervation in Parkinson disease. Description: Yousaf, Tayyabah, et al. Excessive daytime sleepiness may be associated with caudate denervation in Parkinson disease. ''J Neurol Sci''. 2018 Apr 15; '''387''': 220-227
Identification of a prospective early motor progression cluster of Parkinson's disease: Data from the PPMI study. Description: Vavougios, George D, et al. Identification of a prospective early motor progression cluster of Parkinson's disease: Data from the PPMI study. ''J Neurol Sci''. 2018 Apr 15; '''387''': 103-108
Toward defining deep brain stimulation targets in MNI space: A subcortical atlas based on multimodal MRI, histology and structural connectivity. Description: Ewert, Siobhan, et al. Toward defining deep brain stimulation targets in MNI space: A subcortical atlas based on multimodal MRI, histology and structural connectivity. ''Neuroimage''. 2018 Apr 15; '''170''': 271-282
Correlations between CSF proteins and spontaneous neuronal activity in Parkinson's disease. Description: Guo, Tao, et al. Correlations between CSF proteins and spontaneous neuronal activity in Parkinson's disease. ''Neurosci Lett''. 2018 Apr 23; '''673''': 61-66
Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort. Description: Simuni, Tanya, et al. Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort. ''Mov Disord''. 2018 May; '''33''' (5):771-782
Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease. Description: Schulz, Jonathan, et al. Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease. ''Brain''. 2018 May 1; '''141''' (5):1501-1516
Computer-aided diagnosis for ((123)I)FP-CIT imaging: impact on clinical reporting. Description: Taylor, Jonathan Christopher, et al. Computer-aided diagnosis for ((123)I)FP-CIT imaging: impact on clinical reporting. ''EJNMMI Res''. 2018 May 8; '''8''' (1):36
Incorporating spatial constraint in co-activation pattern analysis to explore the dynamics of resting-state networks: An application to Parkinson's disease. Description: Zhuang, Xiaowei, et al. Incorporating spatial constraint in co-activation pattern analysis to explore the dynamics of resting-state networks: An application to Parkinson's disease. ''Neuroimage''. 2018 May 15; '''172''': 64-84
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. Description: Lewczuk, Piotr, et al. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. ''World J Biol Psychiatry''. 2018 Jun; '''19''' (4):244-328
A comparison of publicly available linear MRI stereotaxic registration techniques. Description: Dadar, Mahsa, et al. A comparison of publicly available linear MRI stereotaxic registration techniques. ''Neuroimage''. 2018 Jul 1; '''174''': 191-200
Computational systems biology approaches for Parkinson's disease. Description: Glaab, Enrico. Computational systems biology approaches for Parkinson's disease. ''Cell Tissue Res''. 2018 Jul; '''373''' (1):91-109
Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects. Description: Seo, Youngduk, et al. Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects. ''Yonsei Med J''. 2018 Aug; '''59''' (6):787-792
The factors associated with impulse control behaviors in Parkinson's disease: A 2-year longitudinal retrospective cohort study. Description: Kon, Tomoya, et al. The factors associated with impulse control behaviors in Parkinson's disease: A 2-year longitudinal retrospective cohort study. ''Brain Behav''. 2018 Aug; '''8''' (8):e01036
From hype to reality: data science enabling personalized medicine. Description: Frohlich, Holger, et al. From hype to reality: data science enabling personalized medicine. ''BMC Med''. 2018 Aug 27; '''16''' (1):150
Altered resting-state functional connectivity of the putamen and internal globus pallidus is related to speech impairment in Parkinson's disease. Description: Manes, Jordan L, et al. Altered resting-state functional connectivity of the putamen and internal globus pallidus is related to speech impairment in Parkinson's disease. ''Brain Behav''. 2018 Sep; '''8''' (9):e01073
Can neuroimaging predict dementia in Parkinson's disease? Description: Lanskey, Juliette H, et al. Can neuroimaging predict dementia in Parkinson's disease? ''Brain''. 2018 Sep 1; '''141''' (9):2545-2560
An anatomically curated fiber clustering white matter atlas for consistent white matter tract parcellation across the lifespan. Description: Zhang, Fan, et al. An anatomically curated fiber clustering white matter atlas for consistent white matter tract parcellation across the lifespan. ''Neuroimage''. 2018 Oct 1; '''179''': 429-447
Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease. Description: Gaare, Johannes J, et al. Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease. ''Mov Disord''. 2018 Oct; '''33''' (10):1591-1600
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Description: McWilliams, Thomas G, et al. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. ''Open Biol''. 2018 Nov 7; '''8''' (11):
Functional Connectivity-Based Modelling Simulates Subject-Specific Network Spreading Effects of Focal Brain Stimulation. Description: Chen, Xiaoyu, et al. Functional Connectivity-Based Modelling Simulates Subject-Specific Network Spreading Effects of Focal Brain Stimulation. ''Neurosci Bull''. 2018 Dec; '''34''' (6):921-938
The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort. Description: Marek, Kenneth, et al. The Parkinson's progression markers initiative (PPMI) - establishing a PD biomarker cohort. ''Ann Clin Transl Neurol''. 2018 Dec; '''5''' (12):1460-1477
Cognitive processes that indirectly affect olfactory dysfunction in Parkinson's disease. Description: Mertens, Attakias T, et al. Cognitive processes that indirectly affect olfactory dysfunction in Parkinson's disease. ''Clin Park Relat Disord''. 2019; '''1''': 13-20
Sniffing Out Cognitive Decline in Patients with and without Evidence of Dopaminergic Deficit. Description: Lopez, Francesca V, et al. Sniffing Out Cognitive Decline in Patients with and without Evidence of Dopaminergic Deficit. ''Clin Park Relat Disord''. 2019; '''1''': 77-81
Alteration of Tremor Dominant and Postural Instability Gait Difficulty Subtypes During the Progression of Parkinson's Disease: Analysis of the PPMI Cohort. Description: Lee, Jeong Won, et al. Alteration of Tremor Dominant and Postural Instability Gait Difficulty Subtypes During the Progression of Parkinson's Disease: Analysis of the PPMI Cohort. ''Front Neurol''. 2019; '''10''': 471
Brain MRI Reveals Ascending Atrophy in Parkinson's Disease Across Severity. Description: Blair, Jamie C, et al. Brain MRI Reveals Ascending Atrophy in Parkinson's Disease Across Severity. ''Front Neurol''. 2019; '''10''': 1329
Dysphagia is associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naive Parkinson's patients. Description: Polychronis, Sotirios, et al. Dysphagia is associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naive Parkinson's patients. ''PLoS One''. 2019; '''14''' (7):e0214352
Effect of Single-Nucleotide Polymorphisms on Decline of Dopamine Transporter Availability in Parkinson's Disease. Description: Shin, Seunghyeon, et al. Effect of Single-Nucleotide Polymorphisms on Decline of Dopamine Transporter Availability in Parkinson's Disease. ''J Clin Neurol''. 2019 Jan; '''15''' (1):102-107
Exercise Reverses Dysregulation of T-Cell-Related Function in Blood Leukocytes of Patients With Parkinson's Disease. Description: Hu, Yong, et al. Exercise Reverses Dysregulation of T-Cell-Related Function in Blood Leukocytes of Patients With Parkinson's Disease. ''Front Neurol''. 2019; '''10''': 1389
Increased Cortical Thickness in Attentional Networks in Parkinson's Disease with Minor Hallucinations. Description: Sawczak, Caspian M, et al. Increased Cortical Thickness in Attentional Networks in Parkinson's Disease with Minor Hallucinations. ''Parkinsons Dis''. 2019; '''2019''': 5351749
Machine Learning in Human Olfactory Research. Description: Lotsch, Jorn, et al. Machine Learning in Human Olfactory Research. ''Chem Senses''. 2019 Jan 1; '''44''' (1):11-22
Measuring Anxiety in Patients With Early-Stage Parkinson's Disease: Rasch Analysis of the State-Trait Anxiety Inventory. Description: Yang, Hui-Jun, et al. Measuring Anxiety in Patients With Early-Stage Parkinson's Disease: Rasch Analysis of the State-Trait Anxiety Inventory. ''Front Neurol''. 2019; '''10''': 49
Microstructural White Matter Characteristics in Parkinson's Disease With Depression: A Diffusion Tensor Imaging Replication Study. Description: Lacey, Colleen, et al. Microstructural White Matter Characteristics in Parkinson's Disease With Depression: A Diffusion Tensor Imaging Replication Study. ''Front Neurol''. 2019; '''10''': 884
Parkinson's Disease Detection Using Isosurfaces-Based Features and Convolutional Neural Networks. Description: Ortiz, Andres, et al. Parkinson's Disease Detection Using Isosurfaces-Based Features and Convolutional Neural Networks. ''Front Neuroinform''. 2019; '''13''': 48
Predicting Progression in Parkinson's Disease Using Baseline and 1-Year Change Measures. Description: Chahine, Lana M, et al. Predicting Progression in Parkinson's Disease Using Baseline and 1-Year Change Measures. ''J Parkinsons Dis''. 2019; '''9''' (4):665-679
Striatum Shape Hypertrophy in Early Stage Parkinson's Disease With Excessive Daytime Sleepiness. Description: Gong, Liang, et al. Striatum Shape Hypertrophy in Early Stage Parkinson's Disease With Excessive Daytime Sleepiness. ''Front Neurosci''. 2019; '''13''': 1353
The Combination of DAT-SPECT, Structural and Diffusion MRI Predicts Clinical Progression in Parkinson's Disease. Description: Lorio, Sara, et al. The Combination of DAT-SPECT, Structural and Diffusion MRI Predicts Clinical Progression in Parkinson's Disease. ''Front Aging Neurosci''. 2019; '''11''': 57
The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease. Description: Stephenson, Diane, et al. The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease. ''J Parkinsons Dis''. 2019; '''9''' (3):553-563
White Matter Tract Alterations in Drug-Naive Parkinson's Disease Patients With Excessive Daytime Sleepiness. Description: Ashraf-Ganjouei, Amir, et al. White Matter Tract Alterations in Drug-Naive Parkinson's Disease Patients With Excessive Daytime Sleepiness. ''Front Neurol''. 2019; '''10''': 378
Data-Driven Subtyping of Parkinson's Disease Using Longitudinal Clinical Records: A Cohort Study. Description: Zhang, Xi, et al. Data-Driven Subtyping of Parkinson's Disease Using Longitudinal Clinical Records: A Cohort Study. ''Sci Rep''. 2019 Jan 28; '''9''' (1):797
No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease. Description: Berge-Seidl, Victoria, et al. No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease. ''Neurobiol Aging''. 2019 Feb; '''74''': 236.e1-236.e5
Dopaminergic degeneration induces early posterior cortical thinning in Parkinson's disease. Description: Sampedro, Frederic, et al. Dopaminergic degeneration induces early posterior cortical thinning in Parkinson's disease. ''Neurobiol Dis''. 2019 Apr; '''124''': 29-35
Influence of analytic techniques on comparing DTI-derived measurements in early stage Parkinson's disease. Description: Mishra, Virendra R, et al. Influence of analytic techniques on comparing DTI-derived measurements in early stage Parkinson's disease. ''Heliyon''. 2019 Apr; '''5''' (4):e01481
White Matter Changes Correlates of Peripheral Neuroinflammation in Patients with Parkinson's Disease. Description: Haghshomar, Maryam, et al. White Matter Changes Correlates of Peripheral Neuroinflammation in Patients with Parkinson's Disease. ''Neuroscience''. 2019 Apr 1; '''403''': 70-78
A clinical-anatomical signature of Parkinson's disease identified with partial least squares and magnetic resonance imaging. Description: Zeighami, Yashar, et al. A clinical-anatomical signature of Parkinson's disease identified with partial least squares and magnetic resonance imaging. ''Neuroimage''. 2019 Apr 15; '''190''': 69-78
eBrain: a Three Dimensional Simulation Tool to Study Drug Delivery in the Brain. Description: Setty, Yaki. eBrain: a Three Dimensional Simulation Tool to Study Drug Delivery in the Brain. ''Sci Rep''. 2019 Apr 16; '''9''' (1):6162
Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease. Description: Romero, Klaus, et al. Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease. ''Clin Transl Sci''. 2019 May; '''12''' (3):240-246
Predicting cognitive decline with non-clinical markers in Parkinson's disease (PRECODE-2). Description: Yousaf, Tayyabah, et al. Predicting cognitive decline with non-clinical markers in Parkinson's disease (PRECODE-2). ''J Neurol''. 2019 May; '''266''' (5):1203-1210
Diagnostic performance of the specific uptake size index for semi-quantitative analysis of I-123-FP-CIT SPECT: harmonized multi-center research setting versus typical clinical single-camera setting. Description: Buchert, Ralph, et al. Diagnostic performance of the specific uptake size index for semi-quantitative analysis of I-123-FP-CIT SPECT: harmonized multi-center research setting versus typical clinical single-camera setting. ''EJNMMI Res''. 2019 May 7; '''9''' (1):37
GenePy - a score for estimating gene pathogenicity in individuals using next-generation sequencing data. Description: Mossotto, E, et al. GenePy - a score for estimating gene pathogenicity in individuals using next-generation sequencing data. ''BMC Bioinformatics''. 2019 May 16; '''20''' (1):254
Cerebrospinal fluid biomarker for Parkinson's disease: An overview. Description: Maass, Fabian, et al. Cerebrospinal fluid biomarker for Parkinson's disease: An overview. ''Mol Cell Neurosci''. 2019 Jun; '''97''': 60-66
An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Ass42 and an APOE epsilon4 allele. Description: Shahid, Marian, et al. An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Ass42 and an APOE epsilon4 allele. ''Neurobiol Dis''. 2019 Jul; '''127''': 278-286
Does the MDS-UPDRS provide the precision to assess progression in early Parkinson's disease? Learnings from the Parkinson's progression marker initiative cohort. Description: Regnault, Antoine, et al. Does the MDS-UPDRS provide the precision to assess progression in early Parkinson's disease? Learnings from the Parkinson's progression marker initiative cohort. ''J Neurol''. 2019 Aug; '''266''' (8):1927-1936
Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts. Description: Iwaki, Hirotaka, et al. Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts. ''Neurol Genet''. 2019 Aug; '''5''' (4):e348
Assessment of a prognostic MRI biomarker in early de novo Parkinson's disease. Description: Zeighami, Yashar, et al. Assessment of a prognostic MRI biomarker in early de novo Parkinson's disease. ''Neuroimage Clin''. 2019 Aug 19; '''24''': 101986
Longitudinal analyses of cerebrospinal fluid alpha-Synuclein in prodromal and early Parkinson's disease. Description: Mollenhauer, Brit, et al. Longitudinal analyses of cerebrospinal fluid alpha-Synuclein in prodromal and early Parkinson's disease. ''Mov Disord''. 2019 Sep; '''34''' (9):1354-1364
Clinical implications of early caudate dysfunction in Parkinson's disease. Description: Pasquini, Jacopo, et al. Clinical implications of early caudate dysfunction in Parkinson's disease. ''J Neurol Neurosurg Psychiatry''. 2019 Oct; '''90''' (10):1098-1104
Measuring Parkinson's disease over time: The real-world within-subject reliability of the MDS-UPDRS. Description: Evers, Luc J W, et al. Measuring Parkinson's disease over time: The real-world within-subject reliability of the MDS-UPDRS. ''Mov Disord''. 2019 Oct; '''34''' (10):1480-1487
Smaller subcortical volume in Parkinson patients with rapid eye movement sleep behavior disorder. Description: Kamps, Sanne, et al. Smaller subcortical volume in Parkinson patients with rapid eye movement sleep behavior disorder. ''Brain Imaging Behav''. 2019 Oct; '''13''' (5):1352-1360
Deep learning for clustering of multivariate clinical patient trajectories with missing values. Description: de Jong, Johann, et al. Deep learning for clustering of multivariate clinical patient trajectories with missing values. ''Gigascience''. 2019 Nov 1; '''8''' (11):
Parkinson's disease prognostic scores for progression of cognitive decline. Description: Gramotnev, Galina, et al. Parkinson's disease prognostic scores for progression of cognitive decline. ''Sci Rep''. 2019 Nov 25; '''9''' (1):17485
Predicting severity and prognosis in Parkinson's disease from brain microstructure and connectivity. Description: Abbasi, Nooshin, et al. Predicting severity and prognosis in Parkinson's disease from brain microstructure and connectivity. ''Neuroimage Clin''. 2019 Nov 28; '''25''': 102111
Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson's Disease with Mild Cognitive Impairment. Description: Jia, Xiuqin, et al. Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson's Disease with Mild Cognitive Impairment. ''Aging Dis''. 2019 Dec; '''10''' (6):1221-1232
Altered Brain Functional Network in Parkinson Disease With Rapid Eye Movement Sleep Behavior Disorder. Description: Li, Jiao, et al. Altered Brain Functional Network in Parkinson Disease With Rapid Eye Movement Sleep Behavior Disorder. ''Front Neurol''. 2020; '''11''': 563624
A machine learning-based classification approach on Parkinson's disease diffusion tensor imaging datasets. Description: Prasuhn, Jannik, et al. A machine learning-based classification approach on Parkinson's disease diffusion tensor imaging datasets. ''Neurol Res Pract''. 2020; '''2''': 46
Association Between REM Sleep Behavior Disorder and Cognitive Dysfunctions in Parkinson's Disease: A Systematic Review and Meta-Analysis of Observational Studies. Description: Mao, Jingrong, et al. Association Between REM Sleep Behavior Disorder and Cognitive Dysfunctions in Parkinson's Disease: A Systematic Review and Meta-Analysis of Observational Studies. ''Front Neurol''. 2020; '''11''': 577874
Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. Description: Olney, Nicholas T, et al. Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. ''Alzheimers Dement''. 2020 Jan; '''16''' (1):49-59
Motor Progression in Early-Stage Parkinson's Disease: A Clinical Prediction Model and the Role of Cerebrospinal Fluid Biomarkers. Description: Ma, Ling-Yan, et al. Motor Progression in Early-Stage Parkinson's Disease: A Clinical Prediction Model and the Role of Cerebrospinal Fluid Biomarkers. ''Front Aging Neurosci''. 2020; '''12''': 627199
Narcolepsy in Parkinson's disease with insulin resistance. Description: Chunduri, Alisha, et al. Narcolepsy in Parkinson's disease with insulin resistance. ''F1000Res''. 2020; '''9''': 1361
Single Nucleotide Polymorphisms Associated With Gut Homeostasis Influence Risk and Age-at-Onset of Parkinson's Disease. Description: Gorecki, Anastazja M, et al. Single Nucleotide Polymorphisms Associated With Gut Homeostasis Influence Risk and Age-at-Onset of Parkinson's Disease. ''Front Aging Neurosci''. 2020; '''12''': 603849
Topological Abnormalities of Functional Brain Network in Early-Stage Parkinson's Disease Patients With Mild Cognitive Impairment. Description: Chen, Xiangbin, et al. Topological Abnormalities of Functional Brain Network in Early-Stage Parkinson's Disease Patients With Mild Cognitive Impairment. ''Front Neurosci''. 2020; '''14''': 616872
Urinary Dysfunction Is Associated with Nigrostriatal Dopaminergic Degeneration in Early and Untreated Patients with Parkinson's Disease. Description: Wang, Jing, et al. Urinary Dysfunction Is Associated with Nigrostriatal Dopaminergic Degeneration in Early and Untreated Patients with Parkinson's Disease. ''Parkinsons Dis''. 2020; '''2020''': 4981647
Variational Autoencoder Modular Bayesian Networks for Simulation of Heterogeneous Clinical Study Data. Description: Gootjes-Dreesbach, Luise, et al. Variational Autoencoder Modular Bayesian Networks for Simulation of Heterogeneous Clinical Study Data. ''Front Big Data''. 2020; '''3''': 16
Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson's disease. Description: Kann, Sarah J, et al. Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson's disease. ''NPJ Parkinsons Dis''. 2020; '''6''': 19
Assessing White Matter Pathology in Early-Stage Parkinson Disease Using Diffusion MRI: A Systematic Review. Description: Bergamino, Maurizio, et al. Assessing White Matter Pathology in Early-Stage Parkinson Disease Using Diffusion MRI: A Systematic Review. ''Front Neurol''. 2020; '''11''': 314
Comparison of an Online-Only Parkinson's Disease Research Cohort to Cohorts Assessed In Person. Description: Chahine, Lana M, et al. Comparison of an Online-Only Parkinson's Disease Research Cohort to Cohorts Assessed In Person. ''J Parkinsons Dis''. 2020; '''10''' (2):677-691
Diffusion Tensor Imaging in Parkinson's Disease and Parkinsonian Syndrome: A Systematic Review. Description: Zhang, Yu, et al. Diffusion Tensor Imaging in Parkinson's Disease and Parkinsonian Syndrome: A Systematic Review. ''Front Neurol''. 2020; '''11''': 531993
Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson's Disease. Description: Li, Yanxuan, et al. Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson's Disease. ''Front Aging Neurosci''. 2020; '''12''': 161
Drug and Disease Effects in Parkinson's Psychosis: Revisiting the Role of Dopamine. Description: Dave, Sonali, et al. Drug and Disease Effects in Parkinson's Psychosis: Revisiting the Role of Dopamine. ''Mov Disord Clin Pract''. 2020 Jan; '''7''' (1):32-36
Identifying and predicting Parkinson's disease subtypes through trajectory clustering via bipartite networks. Description: Krishnagopal, Sanjukta, et al. Identifying and predicting Parkinson's disease subtypes through trajectory clustering via bipartite networks. ''PLoS One''. 2020; '''15''' (6):e0233296
Improvement of classification performance of Parkinson's disease using shape features for machine learning on dopamine transporter single photon emission computed tomography. Description: Shiiba, Takuro, et al. Improvement of classification performance of Parkinson's disease using shape features for machine learning on dopamine transporter single photon emission computed tomography. ''PLoS One''. 2020; '''15''' (1):e0228289
Low Cholesterol Level Linked to Reduced Semantic Fluency Performance and Reduced Gray Matter Volume in the Medial Temporal Lobe. Description: Yang, Fan Nils, et al. Low Cholesterol Level Linked to Reduced Semantic Fluency Performance and Reduced Gray Matter Volume in the Medial Temporal Lobe. ''Front Aging Neurosci''. 2020; '''12''': 57
Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson's Disease. Description: Martinez-Ramirez, Daniel, et al. Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson's Disease. ''Parkinsons Dis''. 2020; '''2020''': 1694547
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. Description: Gaare, Johannes Jernqvist, et al. Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. ''PLoS One''. 2020; '''15''' (10):e0239824
Non-motor Clinical and Biomarker Predictors Enable High Cross-Validated Accuracy Detection of Early PD but Lesser Cross-Validated Accuracy Detection of Scans Without Evidence of Dopaminergic Deficit. Description: Leger, Charles, et al. Non-motor Clinical and Biomarker Predictors Enable High Cross-Validated Accuracy Detection of Early PD but Lesser Cross-Validated Accuracy Detection of Scans Without Evidence of Dopaminergic Deficit. ''Front Neurol''. 2020; '''11''': 364
Predict cognitive decline with clinical markers in Parkinson's disease (PRECODE-1). Description: Wilson, Heather, et al. Predict cognitive decline with clinical markers in Parkinson's disease (PRECODE-1). ''J Neural Transm (Vienna)''. 2020 Jan; '''127''' (1):51-59
Progressive brain atrophy in Parkinson's disease patients who convert to mild cognitive impairment. Description: Zhou, Cheng, et al. Progressive brain atrophy in Parkinson's disease patients who convert to mild cognitive impairment. ''CNS Neurosci Ther''. 2020 Jan; '''26''' (1):117-125
Serial Dopamine Transporter Imaging of Nigrostriatal Function in Parkinson's Disease With Probable REM Sleep Behavior Disorder. Description: Cao, Ruihua, et al. Serial Dopamine Transporter Imaging of Nigrostriatal Function in Parkinson's Disease With Probable REM Sleep Behavior Disorder. ''Front Neurosci''. 2020; '''14''': 349
Ten Years of the International Parkinson Disease Genomics Consortium: Progress and Next Steps. Description: Ten Years of the International Parkinson Disease Genomics Consortium: Progress and Next Steps. ''J Parkinsons Dis''. 2020; '''10''' (1):19-30
Circulating cell-free mitochondrial DNA levels in Parkinson's disease are influenced by treatment. Description: Lowes, Hannah, et al. Circulating cell-free mitochondrial DNA levels in Parkinson's disease are influenced by treatment. ''Mol Neurodegener''. 2020 Feb 18; '''15''' (1):10
Constructing treatment episodes from concomitant medication logs: a prospective observational study. Description: Kuramoto, Lisa K, et al. Constructing treatment episodes from concomitant medication logs: a prospective observational study. ''BMJ Open''. 2020 Mar 10; '''10''' (3):e034305
Genetics of Parkinson's disease: An introspection of its journey towards precision medicine. Description: Bandres-Ciga, Sara, et al. Genetics of Parkinson's disease: An introspection of its journey towards precision medicine. ''Neurobiol Dis''. 2020 Apr; '''137''': 104782
Brainstem atrophy in Gulf War Illness. Description: Zhang, Yu, et al. Brainstem atrophy in Gulf War Illness. ''Neurotoxicology''. 2020 May; '''78''': 71-79
Choroid plexus volume is associated with levels of CSF proteins: relevance for Alzheimer's and Parkinson's disease. Description: Tadayon, Ehsan, et al. Choroid plexus volume is associated with levels of CSF proteins: relevance for Alzheimer's and Parkinson's disease. ''Neurobiol Aging''. 2020 May; '''89''': 108-117
T1-weighted MRI-driven Brain Age Estimation in Alzheimer's Disease and Parkinson's Disease. Description: Beheshti, Iman, et al. T1-weighted MRI-driven Brain Age Estimation in Alzheimer's Disease and Parkinson's Disease. ''Aging Dis''. 2020 May; '''11''' (3):618-628
Extrastriatal (123)I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort. Description: Nicastro, Nicolas, et al. Extrastriatal (123)I-FP-CIT SPECT impairment in Parkinson's disease - the PPMI cohort. ''BMC Neurol''. 2020 May 16; '''20''' (1):192
Impact of the size of the normal database on the performance of the specific binding ratio in dopamine transporter SPECT. Description: Schmitz-Steinkruger, Helen, et al. Impact of the size of the normal database on the performance of the specific binding ratio in dopamine transporter SPECT. ''EJNMMI Phys''. 2020 May 20; '''7''' (1):34
Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease. Description: Irwin, David J, et al. Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease. ''Ann Neurol''. 2020 Jun 16;
Transcriptomic differences in MSA clinical variants. Description: Perez-Soriano, Alexandra, et al. Transcriptomic differences in MSA clinical variants. ''Sci Rep''. 2020 Jun 25; '''10''' (1):10310
Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encoders. Description: Sood, Meemansa, et al. Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encoders. ''Sci Rep''. 2020 Jul 3; '''10''' (1):10971
Prediction of age at onset in Parkinson's disease using objective specific neuroimaging genetics based on a sparse canonical correlation analysis. Description: Won, Ji Hye, et al. Prediction of age at onset in Parkinson's disease using objective specific neuroimaging genetics based on a sparse canonical correlation analysis. ''Sci Rep''. 2020 Jul 15; '''10''' (1):11662
The genetic architecture of human brainstem structures and their involvement in common brain disorders. Description: Elvsashagen, Torbjorn, et al. The genetic architecture of human brainstem structures and their involvement in common brain disorders. ''Nat Commun''. 2020 Aug 11; '''11''' (1):4016
From a deep learning model back to the brain-Identifying regional predictors and their relation to aging. Description: Levakov, Gidon, et al. From a deep learning model back to the brain-Identifying regional predictors and their relation to aging. ''Hum Brain Mapp''. 2020 Aug 15; '''41''' (12):3235-3252
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease. Description: Bandres-Ciga, S, et al. Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease. ''Acta Neuropathol''. 2020 Sep; '''140''' (3):341-358
Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. Description: Bobbili, Dheeraj Reddy, et al. Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. ''J Med Genet''. 2020 Sep; '''57''' (9):617-623
Non-Coding RNAs in the Brain-Heart Axis: The Case of Parkinson's Disease. Description: Acharya, Shubhra, et al. Non-Coding RNAs in the Brain-Heart Axis: The Case of Parkinson's Disease. ''Int J Mol Sci''. 2020 Sep 6; '''21''' (18):
Association of specific biotypes in patients with Parkinson disease and disease progression. Description: Wang, Linbo, et al. Association of specific biotypes in patients with Parkinson disease and disease progression. ''Neurology''. 2020 Sep 15; '''95''' (11):e1445-e1460
A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Identifies Disease-Relevant Epivariations and CGG Expansions. Description: Garg, Paras, et al. A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Identifies Disease-Relevant Epivariations and CGG Expansions. ''Am J Hum Genet''. 2020 Oct 1; '''107''' (4):654-669
Deep brain stimulation: Imaging on a group level. Description: Treu, Svenja, et al. Deep brain stimulation: Imaging on a group level. ''Neuroimage''. 2020 Oct 1; '''219''': 117018
Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations. Description: Chandio, Bramsh Qamar, et al. Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations. ''Sci Rep''. 2020 Oct 13; '''10''' (1):17149
Neuroharmony: A new tool for harmonizing volumetric MRI data from unseen scanners. Description: Garcia-Dias, Rafael, et al. Neuroharmony: A new tool for harmonizing volumetric MRI data from unseen scanners. ''Neuroimage''. 2020 Oct 15; '''220''': 117127
Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression. Description: Mollenhauer, Brit, et al. Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression. ''Mov Disord''. 2020 Nov; '''35''' (11):1999-2008
Constipation and sleep behaviour disorder associate with processing speed and attention in males with Parkinson's disease over five years follow-up. Description: Kong, Wee Lee, et al. Constipation and sleep behaviour disorder associate with processing speed and attention in males with Parkinson's disease over five years follow-up. ''Sci Rep''. 2020 Nov 4; '''10''' (1):19014
Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms. Description: Emon, Mohammad Asif, et al. Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms. ''Sci Rep''. 2020 Nov 5; '''10''' (1):19097
Longitudinal evolution of non-motor symptoms according to age at onset in early Parkinson's disease. Description: Kim, Ryul, et al. Longitudinal evolution of non-motor symptoms according to age at onset in early Parkinson's disease. ''J Neurol Sci''. 2020 Nov 15; '''418''': 117157
MRI-visible perivascular spaces are associated with cerebrospinal fluid biomarkers in Parkinson's disease. Description: Fang, Yi, et al. MRI-visible perivascular spaces are associated with cerebrospinal fluid biomarkers in Parkinson's disease. ''Aging (Albany NY)''. 2020 Nov 25; '''12''' (24):25805-25818
Abnormal Topological Network in Parkinson's Disease With Impulse Control Disorders: A Resting-State Functional Magnetic Resonance Imaging Study. Description: Zhu, Xiaopeng, et al. Abnormal Topological Network in Parkinson's Disease With Impulse Control Disorders: A Resting-State Functional Magnetic Resonance Imaging Study. ''Front Neurosci''. 2021; '''15''': 651710
Advanced brain ageing in Parkinson's disease is related to disease duration and individual impairment. Description: Eickhoff, Claudia R, et al. Advanced brain ageing in Parkinson's disease is related to disease duration and individual impairment. ''Brain Commun''. 2021; '''3''' (3):fcab191
Altered Brain Functional Network in Subtypes of Parkinson's Disease: A Dynamic Perspective. Description: Zhu, Junlan, et al. Altered Brain Functional Network in Subtypes of Parkinson's Disease: A Dynamic Perspective. ''Front Aging Neurosci''. 2021; '''13''': 710735
Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease. Description: Bartl, Michael, et al. Biomarkers of neurodegeneration and glial activation validated in Alzheimer's disease assessed in longitudinal cerebrospinal fluid samples of Parkinson's disease. ''PLoS One''. 2021; '''16''' (10):e0257372
Cognitive Decline in Parkinson's Disease: A Subgroup of Extreme Decliners Revealed by a Data-Driven Analysis of Longitudinal Progression. Description: Andersson, Sara, et al. Cognitive Decline in Parkinson's Disease: A Subgroup of Extreme Decliners Revealed by a Data-Driven Analysis of Longitudinal Progression. ''Front Psychol''. 2021; '''12''': 729755
Correlation of Dopaminergic Denervation and the Progression of Autonomic Dysfunctions in Different Clinical Subtypes of Parkinson's Disease. Description: Jeong, Eun Hye, et al. Correlation of Dopaminergic Denervation and the Progression of Autonomic Dysfunctions in Different Clinical Subtypes of Parkinson's Disease. ''Parkinsons Dis''. 2021; '''2021''': 2268651
Development and Validation of a Prognostic Model for Cognitive Impairment in Parkinson's Disease With REM Sleep Behavior Disorder. Description: Chen, Fangzheng, et al. Development and Validation of a Prognostic Model for Cognitive Impairment in Parkinson's Disease With REM Sleep Behavior Disorder. ''Front Aging Neurosci''. 2021; '''13''': 703158
Dopamine genetic risk score predicts impulse control behaviors in Parkinson's disease. Description: Hall, Alison, et al. Dopamine genetic risk score predicts impulse control behaviors in Parkinson's disease. ''Clin Park Relat Disord''. 2021; '''5''': 100113
Dopamine transporter imaging predicts clinically-defined alpha-synucleinopathy in REM sleep behavior disorder. Description: Chahine, Lana M, et al. Dopamine transporter imaging predicts clinically-defined alpha-synucleinopathy in REM sleep behavior disorder. ''Ann Clin Transl Neurol''. 2021 Jan; '''8''' (1):201-212
Extrastriatal SPECT-DAT uptake correlates with clinical and biological features of de novo Parkinson's disease. Description: Sampedro, Frederic, et al. Extrastriatal SPECT-DAT uptake correlates with clinical and biological features of de novo Parkinson's disease. ''Neurobiol Aging''. 2021 Jan; '''97''': 120-128
Interaction-Based Feature Selection Algorithm Outperforms Polygenic Risk Score in Predicting Parkinson's Disease Status. Description: Cope, Justin L, et al. Interaction-Based Feature Selection Algorithm Outperforms Polygenic Risk Score in Predicting Parkinson's Disease Status. ''Front Genet''. 2021; '''12''': 744557
Nigral diffusivity, but not free water, correlates with iron content in Parkinson's disease. Description: Langley, Jason, et al. Nigral diffusivity, but not free water, correlates with iron content in Parkinson's disease. ''Brain Commun''. 2021; '''3''' (4):fcab251
Normative vs. patient-specific brain connectivity in deep brain stimulation. Description: Wang, Qiang, et al. Normative vs. patient-specific brain connectivity in deep brain stimulation. ''Neuroimage''. 2021 Jan 1; '''224''': 117307
Patients with scans without evidence of dopaminergic deficit (SWEDD) do not have early Parkinson's disease: Analysis of the PPMI data. Description: Lee, Jeong Won, et al. Patients with scans without evidence of dopaminergic deficit (SWEDD) do not have early Parkinson's disease: Analysis of the PPMI data. ''PLoS One''. 2021; '''16''' (2):e0246881
Progression of Nonmotor Symptoms in Parkinson's Disease by Sex and Motor Laterality. Description: Kurlawala, Zimple, et al. Progression of Nonmotor Symptoms in Parkinson's Disease by Sex and Motor Laterality. ''Parkinsons Dis''. 2021; '''2021''': 8898887
Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study. Description: Xu, Zheyu, et al. Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study. ''J Neurol''. 2021 Jan; '''268''' (1):312-320
Stability Evaluation of Brain Changes in Parkinson's Disease Based on Machine Learning. Description: Song, Chenggang, et al. Stability Evaluation of Brain Changes in Parkinson's Disease Based on Machine Learning. ''Front Comput Neurosci''. 2021; '''15''': 735991
Subthalamic Stimulation for Camptocormia in Parkinson's Disease: Association of Volume of Tissue Activated and Structural Connectivity with Clinical Effectiveness. Description: Lai, Yijie, et al. Subthalamic Stimulation for Camptocormia in Parkinson's Disease: Association of Volume of Tissue Activated and Structural Connectivity with Clinical Effectiveness. ''J Parkinsons Dis''. 2021; '''11''' (1):199-210
The Parkinson's Disease Progression Neuroimaging Initiative. Description: Zhu, Shiyi, et al. The Parkinson's Disease Progression Neuroimaging Initiative. ''Behav Neurol''. 2021; '''2021''': 2230196
Trajectory Analysis of Orthostatic Hypotension in Parkinson's Disease: Results From Parkinson's Progression Markers Initiative Cohort. Description: Chen, Kui, et al. Trajectory Analysis of Orthostatic Hypotension in Parkinson's Disease: Results From Parkinson's Progression Markers Initiative Cohort. ''Front Aging Neurosci''. 2021; '''13''': 762759
Multimodal phenotypic axes of Parkinson's disease. Description: Markello, Ross D, et al. Multimodal phenotypic axes of Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Jan 5; '''7''' (1):6
Estimating the Effect of Early Treatment Initiation in Parkinson's Disease Using Observational Data. Description: van den Heuvel, Lieneke, et al. Estimating the Effect of Early Treatment Initiation in Parkinson's Disease Using Observational Data. ''Mov Disord''. 2021 Feb; '''36''' (2):407-414
Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease. Description: Tan, Manuela M X, et al. Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease. ''Mov Disord''. 2021 Feb; '''36''' (2):424-433
Association of autonomic symptoms with cerebrospinal fluid biomarkers in Parkinson disease and scans without evidence of dopaminergic deficit. Description: Yu, Zhenwei, et al. Association of autonomic symptoms with cerebrospinal fluid biomarkers in Parkinson disease and scans without evidence of dopaminergic deficit. ''Medicine (Baltimore)''. 2021 Feb 19; '''100''' (7):e24837
Deep learning based automated diagnosis of bone metastases with SPECT thoracic bone images. Description: Lin, Qiang, et al. Deep learning based automated diagnosis of bone metastases with SPECT thoracic bone images. ''Sci Rep''. 2021 Feb 19; '''11''' (1):4223
Open science takes on Parkinson's disease. Description: Riley, Ekemini Au, et al. Open science takes on Parkinson's disease. ''Elife''. 2021 Feb 25; '''10''':
Probable REM sleep behavior disorder is associated with longitudinal cortical thinning in Parkinson's disease. Description: Yoon, Eun Jin, et al. Probable REM sleep behavior disorder is associated with longitudinal cortical thinning in Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Mar 2; '''7''' (1):19
Thalamic morphology predicts the onset of freezing of gait in Parkinson's disease. Description: D'Cruz, Nicholas, et al. Thalamic morphology predicts the onset of freezing of gait in Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Mar 2; '''7''' (1):20
An Item Response Theory-Informed Strategy to Model Total Score Data from Composite Scales. Description: Wellhagen, Gustaf J, et al. An Item Response Theory-Informed Strategy to Model Total Score Data from Composite Scales. ''AAPS J''. 2021 Mar 16; '''23''' (3):45
Assessment of LIN28A variants in Parkinson's disease in large European cohorts. Description: Diez-Fairen, Monica, et al. Assessment of LIN28A variants in Parkinson's disease in large European cohorts. ''Neurobiol Aging''. 2021 Apr; '''100''': 118.e1-118.e3
GP2: The Global Parkinson's Genetics Program. Description: GP2: The Global Parkinson's Genetics Program. ''Mov Disord''. 2021 Apr; '''36''' (4):842-851
Investigating ELOVL7 coding variants in multiple system atrophy. Description: Wernick, Anna I, et al. Investigating ELOVL7 coding variants in multiple system atrophy. ''Neurosci Lett''. 2021 Apr 1; '''749''': 135723
Sequence of clinical and neurodegeneration events in Parkinson's disease progression. Description: Oxtoby, Neil P, et al. Sequence of clinical and neurodegeneration events in Parkinson's disease progression. ''Brain''. 2021 Apr 12; '''144''' (3):975-988
Distinct neural circuits are associated with subclinical neuropsychiatric symptoms in Parkinson's disease. Description: Tinaz, Sule, et al. Distinct neural circuits are associated with subclinical neuropsychiatric symptoms in Parkinson's disease. ''J Neurol Sci''. 2021 Apr 15; '''423''': 117365
Retrospective motion artifact correction of structural MRI images using deep learning improves the quality of cortical surface reconstructions. Description: Duffy, Ben A, et al. Retrospective motion artifact correction of structural MRI images using deep learning improves the quality of cortical surface reconstructions. ''Neuroimage''. 2021 Apr 15; '''230''': 117756
Computational medication regimen for Parkinson's disease using reinforcement learning. Description: Kim, Yejin, et al. Computational medication regimen for Parkinson's disease using reinforcement learning. ''Sci Rep''. 2021 Apr 29; '''11''' (1):9313
Artificial intelligence in single photon emission computed tomography (SPECT) imaging: a narrative review. Description: Shao, Wenyi, et al. Artificial intelligence in single photon emission computed tomography (SPECT) imaging: a narrative review. ''Ann Transl Med''. 2021 May; '''9''' (9):820
Characterizing resting-state networks in Parkinson's disease: A multi-aspect functional connectivity study. Description: Ghasemi, Mahdieh, et al. Characterizing resting-state networks in Parkinson's disease: A multi-aspect functional connectivity study. ''Brain Behav''. 2021 May; '''11''' (5):e02101
Impact of age and sex correction on the diagnostic performance of dopamine transporter SPECT. Description: Schmitz-Steinkruger, Helen, et al. Impact of age and sex correction on the diagnostic performance of dopamine transporter SPECT. ''Eur J Nucl Med Mol Imaging''. 2021 May; '''48''' (5):1445-1459
The Parkinson's Disease DNA Variant Browser. Description: Kim, Jonggeol J, et al. The Parkinson's Disease DNA Variant Browser. ''Mov Disord''. 2021 May; '''36''' (5):1250-1258
Pervasive cis effects of variation in copy number of large tandem repeats on local DNA methylation and gene expression. Description: Garg, Paras, et al. Pervasive cis effects of variation in copy number of large tandem repeats on local DNA methylation and gene expression. ''Am J Hum Genet''. 2021 May 6; '''108''' (5):809-824
Reference SVA insertion polymorphisms are associated with Parkinson's Disease progression and differential gene expression. Description: Pfaff, Abigail L, et al. Reference SVA insertion polymorphisms are associated with Parkinson's Disease progression and differential gene expression. ''NPJ Parkinsons Dis''. 2021 May 25; '''7''' (1):44
Folded concave penalized learning of high-dimensional MRI data in Parkinson's disease. Description: Li, Changcheng, et al. Folded concave penalized learning of high-dimensional MRI data in Parkinson's disease. ''J Neurosci Methods''. 2021 Jun 1; '''357''': 109157
Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease. Description: Toffoli, Marco, et al. Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease. ''Mov Disord''. 2021 Jun; '''36''' (6):1456-1460
A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson's disease. Description: Leung, Kevin H, et al. A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson's disease. ''EJNMMI Res''. 2021 Jun 7; '''11''' (1):52
Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome. Description: Koks, Sulev, et al. Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome. ''Int J Mol Sci''. 2021 Jun 12; '''22''' (12):
Fiber-specific white matter alterations in early-stage tremor-dominant Parkinson's disease. Description: Andica, Christina, et al. Fiber-specific white matter alterations in early-stage tremor-dominant Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Jun 25; '''7''' (1):51
A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease. Description: Pedersen, Camilla Christina, et al. A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Jul 1; '''7''' (1):54
Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease. Description: Blauwendraat, Cornelis, et al. Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease. ''Ann Neurol''. 2021 Jul; '''90''' (1):35-42
Methodological considerations of evaluating the rate of presynaptic dopaminergic denervation in Parkinson disease with radiotracers: Analysis of the PPMI data. Description: Lee, Jeong Won, et al. Methodological considerations of evaluating the rate of presynaptic dopaminergic denervation in Parkinson disease with radiotracers: Analysis of the PPMI data. ''Medicine (Baltimore)''. 2021 Jul 2; '''100''' (26):e26534
TOMM40 '523' poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson's disease. Description: Bakeberg, Megan C, et al. TOMM40 '523' poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson's disease. ''NPJ Parkinsons Dis''. 2021 Jul 7; '''7''' (1):56
Temporal trajectory of biofluid markers in Parkinson's disease. Description: Baek, Min Seok, et al. Temporal trajectory of biofluid markers in Parkinson's disease. ''Sci Rep''. 2021 Jul 20; '''11''' (1):14820
Accelerating Medicines Partnership: Parkinson's Disease. Genetic Resource. Description: Iwaki, Hirotaka, et al. Accelerating Medicines Partnership: Parkinson's Disease. Genetic Resource. ''Mov Disord''. 2021 Aug; '''36''' (8):1795-1804
Activities of daily living as a longitudinal moderator of the effect of autonomic dysfunction on anxiety and depression of Parkinson's patients. Description: Cui, Jing, et al. Activities of daily living as a longitudinal moderator of the effect of autonomic dysfunction on anxiety and depression of Parkinson's patients. ''Brain Behav''. 2021 Aug; '''11''' (8):e2297
Comparison between four published definitions of hyposmia in Parkinson's disease. Description: Kanavou, Sofia, et al. Comparison between four published definitions of hyposmia in Parkinson's disease. ''Brain Behav''. 2021 Aug; '''11''' (8):e2258
Neural signatures of hyperdirect pathway activity in Parkinson's disease. Description: Oswal, Ashwini, et al. Neural signatures of hyperdirect pathway activity in Parkinson's disease. ''Nat Commun''. 2021 Aug 31; '''12''' (1):5185
Frontoparietal network resilience is associated with protection against cognitive decline in Parkinson's disease. Description: Cascone, Arianna D, et al. Frontoparietal network resilience is associated with protection against cognitive decline in Parkinson's disease. ''Commun Biol''. 2021 Sep 1; '''4''' (1):1021
An individualized prediction of time to cognitive impairment in Parkinson's disease: A combined multi-predictor study. Description: Tang, Chunyan, et al. An individualized prediction of time to cognitive impairment in Parkinson's disease: A combined multi-predictor study. ''Neurosci Lett''. 2021 Sep 25; '''762''': 136149
Asymmetric Dopamine Transporter Loss Affects Cognitive and Motor Progression in Parkinson's Disease. Description: Fiorenzato, Eleonora, et al. Asymmetric Dopamine Transporter Loss Affects Cognitive and Motor Progression in Parkinson's Disease. ''Mov Disord''. 2021 Oct; '''36''' (10):2303-2313
Characterizing white matter alterations subject to clinical laterality in drug-naive de novo Parkinson's disease. Description: Xiao, Yiming, et al. Characterizing white matter alterations subject to clinical laterality in drug-naive de novo Parkinson's disease. ''Hum Brain Mapp''. 2021 Oct 1; '''42''' (14):4465-4477
Novel Approach to Movement Disorder Society-Unified Parkinson's Disease Rating Scale Monitoring in Clinical Trials: Longitudinal Item Response Theory Models. Description: Luo, Sheng, et al. Novel Approach to Movement Disorder Society-Unified Parkinson's Disease Rating Scale Monitoring in Clinical Trials: Longitudinal Item Response Theory Models. ''Mov Disord Clin Pract''. 2021 Oct; '''8''' (7):1083-1091
SORL1 mutation in a Greek family with Parkinson's disease and dementia. Description: Xiromerisiou, Georgia, et al. SORL1 mutation in a Greek family with Parkinson's disease and dementia. ''Ann Clin Transl Neurol''. 2021 Oct; '''8''' (10):1961-1969
Application of Deep Learning Models for Automated Identification of Parkinson's Disease: A Review (2011-2021). Description: Loh, Hui Wen, et al. Application of Deep Learning Models for Automated Identification of Parkinson's Disease: A Review (2011-2021). ''Sensors (Basel)''. 2021 Oct 23; '''21''' (21):
Diffusion Measure Changes of Substantia Nigra Subregions and the Ventral Tegmental Area in Newly Diagnosed Parkinson's Disease. Description: Shim, Jae-Hyuk, et al. Diffusion Measure Changes of Substantia Nigra Subregions and the Ventral Tegmental Area in Newly Diagnosed Parkinson's Disease. ''Exp Neurobiol''. 2021 Oct 31; '''30''' (5):365-373
International Multicenter Analysis of Brain Structure Across Clinical Stages of Parkinson's Disease. Description: International Multicenter Analysis of Brain Structure Across Clinical Stages of Parkinson's Disease. ''''. 2021 Nov; '''36''' (11):2583-2594
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease. Description: Russo, Marco J, et al. High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease. ''Acta Neuropathol Commun''. 2021 Nov 6; '''9''' (1):179
White matter changes in drug-naive Parkinson's disease patients with impulse control & probable REM sleep behavior disorders. Description: Dolatshahi, Mahsa, et al. White matter changes in drug-naive Parkinson's disease patients with impulse control & probable REM sleep behavior disorders. ''J Neurol Sci''. 2021 Nov 15; '''430''': 120032
Effect of data leakage in brain MRI classification using 2D convolutional neural networks. Description: Yagis, Ekin, et al. Effect of data leakage in brain MRI classification using 2D convolutional neural networks. ''Sci Rep''. 2021 Nov 19; '''11''' (1):22544
Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease. Description: Lee, Myung Jun, et al. Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease. ''NPJ Parkinsons Dis''. 2021 Nov 26; '''7''' (1):104
Lower Circulating Lymphocyte Count Predicts ApoE epsilon4-Related Cognitive Decline in Parkinson's Disease. Description: Tsukita, Kazuto, et al. Lower Circulating Lymphocyte Count Predicts ApoE epsilon4-Related Cognitive Decline in Parkinson's Disease. ''Mov Disord''. 2021 Dec; '''36''' (12):2969-2971
Practical Application of DaTQUANT with Optimal Threshold for Diagnostic Accuracy of Dopamine Transporter SPECT. Description: Neill, Matthew, et al. Practical Application of DaTQUANT with Optimal Threshold for Diagnostic Accuracy of Dopamine Transporter SPECT. ''Tomography''. 2021 Dec 18; '''7''' (4):980-989
Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk. Description: Lake, Julie, et al. Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk. ''Mov Disord''. 2022 Jan; '''37''' (1):95-105
Neuroinflammation and Immune Changes in Prodromal Parkinson's Disease and Other Synucleinopathies. Description: Terkelsen, Miriam Hojholt, et al. Neuroinflammation and Immune Changes in Prodromal Parkinson's Disease and Other Synucleinopathies. ''J Parkinsons Dis''. 2022; '''12''' (s1):S149-S163
Sex-Related Longitudinal Change of Motor, Non-Motor, and Biological Features in Early Parkinson's Disease. Description: Picillo, Marina, et al. Sex-Related Longitudinal Change of Motor, Non-Motor, and Biological Features in Early Parkinson's Disease. ''J Parkinsons Dis''. 2022; '''12''' (1):421-436
Trait Anxiety as a Risk Factor for Impulse Control Disorders in de novo Parkinson's Disease. Description: Waskowiak, Pauline, et al. Trait Anxiety as a Risk Factor for Impulse Control Disorders in de novo Parkinson's Disease. ''J Parkinsons Dis''. 2022; '''12''' (2):689-697
Alterations in white matter fiber in Parkinson disease across different cognitive stages. Description: Sang, Tian, et al. Alterations in white matter fiber in Parkinson disease across different cognitive stages. ''Neurosci Lett''. 2022 Jan 19; '''769''': 136424
Directed Brain Connectivity Identifies Widespread Functional Network Abnormalities in Parkinson's Disease. Description: Mijalkov, Mite, et al. Directed Brain Connectivity Identifies Widespread Functional Network Abnormalities in Parkinson's Disease. ''Cereb Cortex''. 2022 Jan 22; '''32''' (3):593-607
Disentangling the PIGD classification for the prediction of cognitive impairment in de novo Parkinson's disease. Description: Urso, Daniele, et al. Disentangling the PIGD classification for the prediction of cognitive impairment in de novo Parkinson's disease. ''J Neurol''. 2022 Mar; '''269''' (3):1566-1573
Self-Report versus Clinician Examination in Early Parkinson's Disease. Description: Zolfaghari, Sheida, et al. Self-Report versus Clinician Examination in Early Parkinson's Disease. ''Mov Disord''. 2022 Mar; '''37''' (3):585-597
Sex differences in brain atrophy and cognitive impairment in Parkinson's disease patients with and without probable rapid eye movement sleep behavior disorder. Description: Oltra, Javier, et al. Sex differences in brain atrophy and cognitive impairment in Parkinson's disease patients with and without probable rapid eye movement sleep behavior disorder. ''J Neurol''. 2022 Mar; '''269''' (3):1591-1599
White matter hyperintensities are associated with grey matter atrophy and cognitive decline in Alzheimer's disease and frontotemporal dementia. Description: Dadar, Mahsa, et al. White matter hyperintensities are associated with grey matter atrophy and cognitive decline in Alzheimer's disease and frontotemporal dementia. ''Neurobiol Aging''. 2022 Mar; '''111''': 54-63
Large-scale societal dynamics are reflected in human mood and brain. Description: Lebedev, Alexander V, et al. Large-scale societal dynamics are reflected in human mood and brain. ''Sci Rep''. 2022 Mar 17; '''12''' (1):4646
Multi-modality machine learning predicting Parkinson's disease. Description: Makarious, Mary B, et al. Multi-modality machine learning predicting Parkinson's disease. ''NPJ Parkinsons Dis''. 2022 Apr 1; '''8''' (1):35
Machine Learning for Early Parkinson's Disease Identification within SWEDD Group Using Clinical and DaTSCAN SPECT Imaging Features. Description: Khachnaoui, Hajer, et al. Machine Learning for Early Parkinson's Disease Identification within SWEDD Group Using Clinical and DaTSCAN SPECT Imaging Features. ''J Imaging''. 2022 Apr 2; '''8''' (4):
Evolution patterns of probable REM sleep behavior disorder predicts Parkinson's disease progression. Description: Ye, Guanyu, et al. Evolution patterns of probable REM sleep behavior disorder predicts Parkinson's disease progression. ''NPJ Parkinsons Dis''. 2022 Apr 5; '''8''' (1):36
Antagonistic network signature of motor function in Parkinson's disease revealed by connectome-based predictive modeling. Description: Wang, Xuyang, et al. Antagonistic network signature of motor function in Parkinson's disease revealed by connectome-based predictive modeling. ''NPJ Parkinsons Dis''. 2022 Apr 22; '''8''' (1):49
Validation of an automatic tool for the rapid measurement of brain atrophy and white matter hyperintensity: QyScore(R). Description: Cavedo, Enrica, et al. Validation of an automatic tool for the rapid measurement of brain atrophy and white matter hyperintensity: QyScore(R). ''Eur Radiol''. 2022 May; '''32''' (5):2949-2961
Explainable machine learning with pairwise interactions for the classification of Parkinson's disease and SWEDD from clinical and imaging features. Description: Sarica, Alessia, et al. Explainable machine learning with pairwise interactions for the classification of Parkinson's disease and SWEDD from clinical and imaging features. ''Brain Imaging Behav''. 2022 May 26;
Regional changes of brain structure during progression of idiopathic Parkinson's disease - A longitudinal study using deformation based morphometry. Description: Pieperhoff, Peter, et al. Regional changes of brain structure during progression of idiopathic Parkinson's disease - A longitudinal study using deformation based morphometry. ''Cortex''. 2022 Jun; '''151''': 188-210
Role of Lysosomal Gene Variants in Modulating GBA-Associated Parkinson's Disease Risk. Description: Straniero, Letizia, et al. Role of Lysosomal Gene Variants in Modulating GBA-Associated Parkinson's Disease Risk. ''Mov Disord''. 2022 Jun; '''37''' (6):1202-1210
A phenome-wide association study identifies effects of copy-number variation of VNTRs and multicopy genes on multiple human traits. Description: Garg, Paras, et al. A phenome-wide association study identifies effects of copy-number variation of VNTRs and multicopy genes on multiple human traits. ''Am J Hum Genet''. 2022 Jun 2; '''109''' (6):1065-1076
Dopamine transporter single-photon emission computed tomography-derived radiomics signature for detecting Parkinson's disease. Description: Shiiba, Takuro, et al. Dopamine transporter single-photon emission computed tomography-derived radiomics signature for detecting Parkinson's disease. ''EJNMMI Res''. 2022 Jun 27; '''12''' (1):39
A model-based approach to assess reproducibility for large-scale high-throughput MRI-based studies. Description: Jiao, Zeyu, et al. A model-based approach to assess reproducibility for large-scale high-throughput MRI-based studies. ''Neuroimage''. 2022 Jul 15; '''255''': 119166
Mapping microstructural gradients of the human striatum in normal aging and Parkinson's disease. Description: Drori, Elior, et al. Mapping microstructural gradients of the human striatum in normal aging and Parkinson's disease. ''Sci Adv''. 2022 Jul 15; '''8''' (28):eabm1971
DARQ: Deep learning of quality control for stereotaxic registration of human brain MRI to the T1w MNI-ICBM 152 template. Description: Fonov, Vladimir S, et al. DARQ: Deep learning of quality control for stereotaxic registration of human brain MRI to the T1w MNI-ICBM 152 template. ''Neuroimage''. 2022 Aug 15; '''257''': 119266
Olfaction and apathy in early idiopathic Parkinson's disease. Description: Martinez-Nunez, Alfonso E, et al. Olfaction and apathy in early idiopathic Parkinson's disease. ''J Neurol Sci''. 2022 Aug 15; '''439''': 120314
Beta amyloid deposition and cognitive decline in Parkinson's disease: a study of the PPMI cohort. Description: Mihaescu, Alexander S, et al. Beta amyloid deposition and cognitive decline in Parkinson's disease: a study of the PPMI cohort. ''Mol Brain''. 2022 Sep 13; '''15''' (1):79
Application of longitudinal item response theory models to modeling Parkinson's disease progression. Description: Zou, Haotian, et al. Application of longitudinal item response theory models to modeling Parkinson's disease progression. ''CPT Pharmacometrics Syst Pharmacol''. 2022 Oct; '''11''' (10):1382-1392
Brain functional network abnormalities in parkinson's disease with mild cognitive impairment. Description: Suo, Xueling, et al. Brain functional network abnormalities in parkinson's disease with mild cognitive impairment. ''Cereb Cortex''. 2022 Oct 20; '''32''' (21):4857-4868
Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort. Description: Simuni, Tanya, et al. Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort. ''NPJ Parkinsons Dis''. 2022 Oct 22; '''8''' (1):140
Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity. Description: Ran, Chen, et al. Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity. ''Hum Brain Mapp''. 2022 Nov; '''43''' (16):5017-5031
Motor symptoms in Parkinson's disease are related to the interplay between cortical curvature and thickness. Description: Almgren, Hannes, et al. Motor symptoms in Parkinson's disease are related to the interplay between cortical curvature and thickness. ''Neuroimage Clin''. 2022 Dec 21; '''37''': 103300
Baseline cerebral structural morphology predict freezing of gait in early drug-naive Parkinson's disease. Description: Li, Yuting, et al. Baseline cerebral structural morphology predict freezing of gait in early drug-naive Parkinson's disease. ''NPJ Parkinsons Dis''. 2022 Dec 29; '''8''' (1):176
Altered dynamic functional network connectivity in drug-naive Parkinson's disease patients with excessive daytime sleepiness. Description: Tan, Zhiyi, et al. Altered dynamic functional network connectivity in drug-naive Parkinson's disease patients with excessive daytime sleepiness. ''Front Aging Neurosci''. 2023; '''15''': 1282962
Freezing of gait is a risk factor for cognitive decline in Parkinson's disease. Description: Qu, Yi, et al. Freezing of gait is a risk factor for cognitive decline in Parkinson's disease. ''J Neurol''. 2023 Jan; '''270''' (1):466-476
Genome- and Exome-Wide Association Studies Revealed Candidate Genes Associated with DaTscan Imaging Features. Description: Yaghoobi, Arash, et al. Genome- and Exome-Wide Association Studies Revealed Candidate Genes Associated with DaTscan Imaging Features. ''Parkinsons Dis''. 2023; '''2023''': 2893662
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration. Description: Ryan, Sean K, et al. Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration. ''Nat Neurosci''. 2023 Jan; '''26''' (1):12-26
Network connectivity and local transcriptomic vulnerability underpin cortical atrophy progression in Parkinson's disease. Description: Vo, Andrew, et al. Network connectivity and local transcriptomic vulnerability underpin cortical atrophy progression in Parkinson's disease. ''Neuroimage Clin''. 2023; '''40''': 103523
Neurodegenerative disease of the brain: a survey of interdisciplinary approaches. Description: Davenport, Franca, et al. Neurodegenerative disease of the brain: a survey of interdisciplinary approaches. ''J R Soc Interface''. 2023 Jan; '''20''' (198):20220406
Nomogram for Early Prediction of Parkinson's Disease Based on microRNA Profiles and Clinical Variables. Description: Hou, Xiangqing, et al. Nomogram for Early Prediction of Parkinson's Disease Based on microRNA Profiles and Clinical Variables. ''J Parkinsons Dis''. 2023; '''13''' (4):473-484
Nomogram to Predict the Probability of Functional Dependence in Early Parkinson's Disease. Description: Valent, Dora, et al. Nomogram to Predict the Probability of Functional Dependence in Early Parkinson's Disease. ''J Parkinsons Dis''. 2023; '''13''' (1):49-55
Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor Parkinson's Disease Progression. Description: Brumm, Michael C, et al. Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor Parkinson's Disease Progression. ''J Parkinsons Dis''. 2023; '''13''' (6):899-916
Serum Uric Acid as a Putative Biomarker in Prodromal Parkinson's Disease: Longitudinal Data from the PPMI Study. Description: Koros, Christos, et al. Serum Uric Acid as a Putative Biomarker in Prodromal Parkinson's Disease: Longitudinal Data from the PPMI Study. ''J Parkinsons Dis''. 2023; '''13''' (5):811-818
Sex Differences in Brain Structure in de novo Parkinson's Disease: A Cross-Sectional and Longitudinal Neuroimaging Study. Description: Li, Hui, et al. Sex Differences in Brain Structure in de novo Parkinson's Disease: A Cross-Sectional and Longitudinal Neuroimaging Study. ''J Parkinsons Dis''. 2023; '''13''' (5):785-795
The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study. Description: Stewart, Charlotte B, et al. The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study. ''Front Neurol''. 2023; '''14''': 1155669
Topological analysis of functional connectivity in Parkinson's disease. Description: Zhang, Weiwei, et al. Topological analysis of functional connectivity in Parkinson's disease. ''Front Neurosci''. 2023; '''17''': 1236128
Transcriptome Analysis Reveals a Two-Gene Signature Links to Motor Progression and Alterations of Immune Cells in Parkinson's Disease. Description: Li, Weimin, et al. Transcriptome Analysis Reveals a Two-Gene Signature Links to Motor Progression and Alterations of Immune Cells in Parkinson's Disease. ''J Parkinsons Dis''. 2023; '''13''' (1):25-38
BundleWarp, streamline-based nonlinear registration of white matter tracts. Description: Chandio, Bramsh Qamar, et al. BundleWarp, streamline-based nonlinear registration of white matter tracts. ''bioRxiv''. 2023 Jan 5;
Peripheral inflammatory immune response differs among sporadic and familial Parkinson's disease. Description: Munoz-Delgado, Laura, et al. Peripheral inflammatory immune response differs among sporadic and familial Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Jan 31; '''9''' (1):12
DBSegment: Fast and robust segmentation of deep brain structures considering domain generalization. Description: Baniasadi, Mehri, et al. DBSegment: Fast and robust segmentation of deep brain structures considering domain generalization. ''Hum Brain Mapp''. 2023 Feb 1; '''44''' (2):762-778
Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation. Description: Martin-Trujillo, Alejandro, et al. Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation. ''Genome Res''. 2023 Feb; '''33''' (2):184-196
A proteogenomic view of Parkinson's disease causality and heterogeneity. Description: Kaiser, Sergio, et al. A proteogenomic view of Parkinson's disease causality and heterogeneity. ''NPJ Parkinsons Dis''. 2023 Feb 11; '''9''' (1):24
LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts. Description: Merchant, Kalpana M, et al. LRRK2 and GBA1 variant carriers have higher urinary bis(monacylglycerol) phosphate concentrations in PPMI cohorts. ''NPJ Parkinsons Dis''. 2023 Feb 28; '''9''' (1):30
Association of rare variants in ARSA with Parkinson's disease. Description: Senkevich, Konstantin, et al. Association of rare variants in ARSA with Parkinson's disease. ''medRxiv''. 2023 Mar 13;
Lifespan Neurodegeneration Of The Human Brain In Multiple Sclerosis. Description: Coupe, Pierrick, et al. Lifespan Neurodegeneration Of The Human Brain In Multiple Sclerosis. ''bioRxiv''. 2023 Mar 14;
Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson's disease. Description: Gomes, Sara, et al. Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Apr 4; '''9''' (1):52
The systematic comparison between Gaussian mirror and Model-X knockoff models. Description: Chen, Shuai, et al. The systematic comparison between Gaussian mirror and Model-X knockoff models. ''Sci Rep''. 2023 Apr 4; '''13''' (1):5478
Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson's disease. Description: Alvarez Jerez, Pilar, et al. Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Apr 6; '''9''' (1):54
Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson's disease. Description: Senkevich, Konstantin, et al. Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson's disease. ''medRxiv''. 2023 Apr 15;
Explainable classification of Parkinson's disease using deep learning trained on a large multi-center database of T1-weighted MRI datasets. Description: Camacho, Milton, et al. Explainable classification of Parkinson's disease using deep learning trained on a large multi-center database of T1-weighted MRI datasets. ''Neuroimage Clin''. 2023 Apr 17; '''38''': 103405
Updated Percentiles for the University of Pennsylvania Smell Identification Test in Adults 50 Years of Age and Older. Description: Brumm, Michael C, et al. Updated Percentiles for the University of Pennsylvania Smell Identification Test in Adults 50 Years of Age and Older. ''Neurology''. 2023 Apr 18; '''100''' (16):e1691-e1701
Estimating uncertainty in read-out patterns: Application to controls-based denoising and voxel-based morphometry patterns in neurodegenerative and neuropsychiatric diseases. Description: Blum, Dominik, et al. Estimating uncertainty in read-out patterns: Application to controls-based denoising and voxel-based morphometry patterns in neurodegenerative and neuropsychiatric diseases. ''Hum Brain Mapp''. 2023 May; '''44''' (7):2802-2814
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. Description: Yu, Meigen, et al. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. ''PLoS Genet''. 2023 May; '''19''' (5):e1010760
Long-term cognitive decline prediction based on multi-modal data using Multimodal3DSiameseNet: transfer learning from Alzheimer's disease to Parkinson's disease. Description: Ostertag, Cecilia, et al. Long-term cognitive decline prediction based on multi-modal data using Multimodal3DSiameseNet: transfer learning from Alzheimer's disease to Parkinson's disease. ''Int J Comput Assist Radiol Surg''. 2023 May; '''18''' (5):809-818
Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia. Description: Real, Raquel, et al. Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia. ''Brain''. 2023 May 2; '''146''' (5):1873-1887
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. Description: Senkevich, Konstantin, et al. GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. ''Brain''. 2023 May 2; '''146''' (5):1859-1872
Moderating effects of uric acid and sex on cognition and psychiatric symptoms in asymmetric Parkinson's disease. Description: Constantin, Ioana Medeleine, et al. Moderating effects of uric acid and sex on cognition and psychiatric symptoms in asymmetric Parkinson's disease. ''Biol Sex Differ''. 2023 May 4; '''14''' (1):26
Radiomic tractometry: a rich and tract-specific class of imaging biomarkers for neuroscience and medical applications. Description: Neher, Peter, et al. Radiomic tractometry: a rich and tract-specific class of imaging biomarkers for neuroscience and medical applications. ''Res Sq''. 2023 May 23;
Genetic meta-analysis of levodopa induced dyskinesia in Parkinson's disease. Description: Martinez-Carrasco, Alejandro, et al. Genetic meta-analysis of levodopa induced dyskinesia in Parkinson's disease. ''medRxiv''. 2023 May 30;
Deep fiber clustering: Anatomically informed fiber clustering with self-supervised deep learning for fast and effective tractography parcellation. Description: Chen, Yuqian, et al. Deep fiber clustering: Anatomically informed fiber clustering with self-supervised deep learning for fast and effective tractography parcellation. ''Neuroimage''. 2023 Jun; '''273''': 120086
Dissociable effects of dopaminergic medications on depression symptom dimensions in Parkinson's disease. Description: Costello, Harry, et al. Dissociable effects of dopaminergic medications on depression symptom dimensions in Parkinson's disease. ''medRxiv''. 2023 Jun 30;
Age and sex differentially shape brain networks in Parkinson's disease. Description: Chen, Zhichun, et al. Age and sex differentially shape brain networks in Parkinson's disease. ''CNS Neurosci Ther''. 2023 Jul; '''29''' (7):1907-1922
Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease. Description: Irmady, Krithi, et al. Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease. ''Nat Commun''. 2023 Jul 5; '''14''' (1):3956
A beginner's guide into curated analyses of open access datasets for biomarker discovery in neurodegeneration. Description: Gomes Moreira, Diana, et al. A beginner's guide into curated analyses of open access datasets for biomarker discovery in neurodegeneration. ''Sci Data''. 2023 Jul 6; '''10''' (1):432
Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease. Description: Phillips, Bridget, et al. Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Jul 8; '''9''' (1):107
Two distinct trajectories of clinical and neurodegeneration events in Parkinson's disease. Description: Zhou, Cheng, et al. Two distinct trajectories of clinical and neurodegeneration events in Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Jul 13; '''9''' (1):111
Current coffee consumption is associated with decreased striatal dopamine transporter availability in Parkinson's disease patients and healthy controls. Description: Wang, Chao, et al. Current coffee consumption is associated with decreased striatal dopamine transporter availability in Parkinson's disease patients and healthy controls. ''BMC Med''. 2023 Jul 25; '''21''' (1):272
Longitudinal cognitive changes in patients with early Parkinson's disease and neuropsychiatric symptoms. Description: Meng, Detao, et al. Longitudinal cognitive changes in patients with early Parkinson's disease and neuropsychiatric symptoms. ''CNS Neurosci Ther''. 2023 Aug; '''29''' (8):2259-2266
Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies. Description: Rahayel, Shady, et al. Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies. ''Brain''. 2023 Aug 1; '''146''' (8):3301-3318
Machine learning-based prediction of longitudinal cognitive decline in early Parkinson's disease using multimodal features. Description: Almgren, Hannes, et al. Machine learning-based prediction of longitudinal cognitive decline in early Parkinson's disease using multimodal features. ''Sci Rep''. 2023 Aug 14; '''13''' (1):13193
Nigral volume loss in prodromal, early, and moderate Parkinson's disease. Description: Langley, Jason, et al. Nigral volume loss in prodromal, early, and moderate Parkinson's disease. ''medRxiv''. 2023 Aug 20;
Reference LINE-1 insertion polymorphisms correlate with Parkinson's disease progression and differential transcript expression in the PPMI cohort. Description: Frohlich, Alexander, et al. Reference LINE-1 insertion polymorphisms correlate with Parkinson's disease progression and differential transcript expression in the PPMI cohort. ''Sci Rep''. 2023 Aug 24; '''13''' (1):13857
The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson's disease. Description: Gabbert, Carolin, et al. The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson's disease. ''medRxiv''. 2023 Aug 25;
Classification of Parkinson's Disease in Patch-Based MRI of Substantia Nigra. Description: Hussain, Sayyed Shahid, et al. Classification of Parkinson's Disease in Patch-Based MRI of Substantia Nigra. ''Diagnostics (Basel)''. 2023 Aug 31; '''13''' (17):
Alternative splicing impacts microRNA regulation within coding regions. Description: Hackl, Lena Maria, et al. Alternative splicing impacts microRNA regulation within coding regions. ''NAR Genom Bioinform''. 2023 Sep; '''5''' (3):lqad081
An Individualized Tractography Pipeline for the Nucleus Basalis of Meynert Lateral Tract. Description: Crockett, Rachel A, et al. An Individualized Tractography Pipeline for the Nucleus Basalis of Meynert Lateral Tract. ''medRxiv''. 2023 Sep 1;
No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment. Description: Crockett, Rachel A, et al. No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment. ''Neurobiol Dis''. 2023 Sep; '''185''': 106243
The effects of AQP4 rs162009 on resting-state brain activity in Parkinson's disease. Description: Jiang, Mengze, et al. The effects of AQP4 rs162009 on resting-state brain activity in Parkinson's disease. ''CNS Neurosci Ther''. 2023 Sep; '''29''' (9):2645-2655
Autonomic function and motor subtypes in Parkinson's disease: a multicentre cross-sectional study. Description: Gu, Si-Chun, et al. Autonomic function and motor subtypes in Parkinson's disease: a multicentre cross-sectional study. ''Sci Rep''. 2023 Sep 4; '''13''' (1):14548
Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson's disease. Description: Yang, Dehao, et al. Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson's disease. ''NPJ Parkinsons Dis''. 2023 Sep 12; '''9''' (1):132
CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer s disease. Description: Del Campo, Marta, et al. CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer s disease. ''Nat Commun''. 2023 Sep 13; '''14''' (1):5635
Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia. Description: Sosero, Yuri L, et al. Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia. ''medRxiv''. 2023 Sep 20;
Invasive neurophysiology and whole brain connectomics for neural decoding in patients with brain implants. Description: Merk, Timon, et al. Invasive neurophysiology and whole brain connectomics for neural decoding in patients with brain implants. ''Res Sq''. 2023 Sep 20;
Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson's disease. Description: Senkevich, Konstantin, et al. Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson's disease. ''medRxiv''. 2023 Sep 23;
Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease. Description: Khan, Ahmed Faraz, et al. Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease. ''Nat Commun''. 2023 Sep 26; '''14''' (1):6009
Association of coffee consumption and striatal volume in patients with Parkinson's disease and healthy controls. Description: Wang, Chao, et al. Association of coffee consumption and striatal volume in patients with Parkinson's disease and healthy controls. ''CNS Neurosci Ther''. 2023 Oct; '''29''' (10):2800-2810
Longitudinal decline in striatal dopamine transporter binding in Parkinson's disease: associations with apathy and anhedonia. Description: Costello, Harry, et al. Longitudinal decline in striatal dopamine transporter binding in Parkinson's disease: associations with apathy and anhedonia. ''J Neurol Neurosurg Psychiatry''. 2023 Oct; '''94''' (10):863-870
Parallel neurodegenerative phenotypes in sporadic Parkinson's disease fibroblasts and midbrain dopamine neurons. Description: Corenblum, M J, et al. Parallel neurodegenerative phenotypes in sporadic Parkinson's disease fibroblasts and midbrain dopamine neurons. ''Prog Neurobiol''. 2023 Oct; '''229''': 102501
Style transfer generative adversarial networks to harmonize multisite MRI to a single reference image to avoid overcorrection. Description: Liu, Mengting, et al. Style transfer generative adversarial networks to harmonize multisite MRI to a single reference image to avoid overcorrection. ''Hum Brain Mapp''. 2023 Oct 1; '''44''' (14):4875-4892
Effects of MRI scanner manufacturers in classification tasks with deep learning models. Description: Kushol, Rafsanjany, et al. Effects of MRI scanner manufacturers in classification tasks with deep learning models. ''Sci Rep''. 2023 Oct 5; '''13''' (1):16791
Predicting cognitive decline in a low-dimensional representation of brain morphology. Description: Lamontagne-Caron, Remi, et al. Predicting cognitive decline in a low-dimensional representation of brain morphology. ''Sci Rep''. 2023 Oct 5; '''13''' (1):16793
Federated Learning for multi-omics: a performance evaluation in Parkinson's disease. Description: Danek, Benjamin, et al. Federated Learning for multi-omics: a performance evaluation in Parkinson's disease. ''bioRxiv''. 2023 Oct 6;
Salience network and cognitive impairment in Parkinson's disease. Description: Yeager, Brooke E, et al. Salience network and cognitive impairment in Parkinson's disease. ''medRxiv''. 2023 Oct 14;
MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease. Description: Vijayakumari, Anupa A, et al. MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease. ''Sci Rep''. 2023 Oct 17; '''13''' (1):17704
Urinary incontinence-related effects on functional connectivity circuits in persons with Parkinson's disease. Description: Denmon, Chanse, et al. Urinary incontinence-related effects on functional connectivity circuits in persons with Parkinson's disease. ''Neurourol Urodyn''. 2023 Nov; '''42''' (8):1694-1701
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Description: Jones-Tabah, Jace, et al. The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. ''bioRxiv''. 2023 Nov 15;
Association between the blood pressure variability and cognitive decline in Parkinson's disease. Description: Xiao, Yi, et al. Association between the blood pressure variability and cognitive decline in Parkinson's disease. ''Brain Behav''. 2023 Dec; '''13''' (12):e3319
Lifespan neurodegeneration of the human brain in multiple sclerosis. Description: Coupe, Pierrick, et al. Lifespan neurodegeneration of the human brain in multiple sclerosis. ''Hum Brain Mapp''. 2023 Dec 1; '''44''' (17):5602-5611
Predictors of dopamine dysregulation syndrome in patients with early Parkinson's disease. Description: Liang, Keke, et al. Predictors of dopamine dysregulation syndrome in patients with early Parkinson's disease. ''Neurol Sci''. 2023 Dec; '''44''' (12):4333-4342
Seed amplification assay results illustrate discrepancy in Parkinson's disease clinical diagnostic accuracy and error rates. Description: Middleton, John Stephen, et al. Seed amplification assay results illustrate discrepancy in Parkinson's disease clinical diagnostic accuracy and error rates. ''J Neurol''. 2023 Dec; '''270''' (12):5813-5818
Structural connectivity from DTI to predict mild cognitive impairment in de novo Parkinson's disease. Description: Huang, Xiaofei, et al. Structural connectivity from DTI to predict mild cognitive impairment in de novo Parkinson's disease. ''Neuroimage Clin''. 2023 Dec 2; '''41''': 103548
Prediction of dyskinesia in Parkinson's disease patients using machine learning algorithms. Description: Leal, Denisson Augusto Bastos, et al. Prediction of dyskinesia in Parkinson's disease patients using machine learning algorithms. ''Sci Rep''. 2023 Dec 16; '''13''' (1):22426
A multi-center distributed learning approach for Parkinson's disease classification using the traveling model paradigm. Description: Souza, Raissa, et al. A multi-center distributed learning approach for Parkinson's disease classification using the traveling model paradigm. ''Front Artif Intell''. 2024; '''7''': 1301997
Assessment tools for cognitive performance in Parkinson's disease and its genetic contributors. Description: Cao, Ling-Xiao, et al. Assessment tools for cognitive performance in Parkinson's disease and its genetic contributors. ''Front Neurol''. 2024; '''15''': 1413187
A systematic review of automated methods to perform white matter tract segmentation. Description: Joshi, Ankita, et al. A systematic review of automated methods to perform white matter tract segmentation. ''Front Neurosci''. 2024; '''18''': 1376570
Comparison between morphometry and radiomics: detecting normal brain aging based on grey matter. Description: Yan, Yuting, et al. Comparison between morphometry and radiomics: detecting normal brain aging based on grey matter. ''Front Aging Neurosci''. 2024; '''16''': 1366780
Cortical and subcortical functional connectivity and cognitive impairment in Parkinson's disease. Description: Yeager, Brooke E, et al. Cortical and subcortical functional connectivity and cognitive impairment in Parkinson's disease. ''Neuroimage Clin''. 2024; '''42''': 103610
DiMANI: diffusion MRI for anatomical nuclei imaging-Application for the direct visualization of thalamic subnuclei. Description: Patriat, Remi, et al. DiMANI: diffusion MRI for anatomical nuclei imaging-Application for the direct visualization of thalamic subnuclei. ''Front Hum Neurosci''. 2024; '''18''': 1324710
Exposure to household pesticides and Parkinson's disease in the Parkinson's Progression Markers Initiative cohort. Description: Santos-Lobato, Bruno Lopes, et al. Exposure to household pesticides and Parkinson's disease in the Parkinson's Progression Markers Initiative cohort. ''Front Neurol''. 2024; '''15''': 1411468
Fine-grained features characterize hippocampal and amygdaloid change pattern in Parkinson's disease and discriminate cognitive-deficit subtype. Description: Zhang, Lingyu, et al. Fine-grained features characterize hippocampal and amygdaloid change pattern in Parkinson's disease and discriminate cognitive-deficit subtype. ''CNS Neurosci Ther''. 2024 Jan; '''30''' (1):e14480
Identification of Parkinson's disease subtypes with distinct brain atrophy progression and its association with clinical progression. Description: Pan, Guoqing, et al. Identification of Parkinson's disease subtypes with distinct brain atrophy progression and its association with clinical progression. ''Psychoradiology''. 2024; '''4''': kkae002
Longitudinal brain structure changes in Parkinson's disease: A replication study. Description: Sokolowski, Andrzej, et al. Longitudinal brain structure changes in Parkinson's disease: A replication study. ''PLoS One''. 2024; '''19''' (1):e0295069
Microstructural alterations in white matter and related neurobiology based on the new clinical subtypes of Parkinson's disease. Description: Yuan, Xiaorong, et al. Microstructural alterations in white matter and related neurobiology based on the new clinical subtypes of Parkinson's disease. ''Front Neurosci''. 2024; '''18''': 1439443
Modeling of Parkinson's Disease Progression and Implications for Detection of Disease Modification in Treatment Trials. Description: Ribba, Benjamin, et al. Modeling of Parkinson's Disease Progression and Implications for Detection of Disease Modification in Treatment Trials. ''J Parkinsons Dis''. 2024; '''14''' (6):1225-1235
Motor dysfunction in Parkinson's patients: depression differences in a latent growth model. Description: Wang, QiuShuang, et al. Motor dysfunction in Parkinson's patients: depression differences in a latent growth model. ''Front Aging Neurosci''. 2024; '''16''': 1393887
Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. Description: Gomez Ramos, Borja, et al. Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. ''EMBO Rep''. 2024 Jan; '''25''' (1):254-285
Occupational Pesticide Exposure in Parkinson's Disease Related to GBA and LRRK2 Variants. Description: Brown, Ethan G, et al. Occupational Pesticide Exposure in Parkinson's Disease Related to GBA and LRRK2 Variants. ''J Parkinsons Dis''. 2024; '''14''' (4):737-746
Predicting the occurrence of mild cognitive impairment in Parkinson's disease using structural MRI data. Description: Beheshti, Iman, et al. Predicting the occurrence of mild cognitive impairment in Parkinson's disease using structural MRI data. ''Front Neurosci''. 2024; '''18''': 1375395
Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson's disease. Description: Kulski, Jerzy K, et al. Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson's disease. ''Front Immunol''. 2024; '''15''': 1349030
SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson's disease. Description: Petkova-Kirova, Polina, et al. SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson's disease. ''Front Pharmacol''. 2024; '''15''': 1477009
Sparse Deep Neural Network for Encoding and Decoding the Structural Connectome. Description: Singh, Satya P, et al. Sparse Deep Neural Network for Encoding and Decoding the Structural Connectome. ''IEEE J Transl Eng Health Med''. 2024; '''12''': 371-381
Staging of progressive supranuclear palsy-Richardson syndrome using MRI brain charts for the human lifespan. Description: Planche, Vincent, et al. Staging of progressive supranuclear palsy-Richardson syndrome using MRI brain charts for the human lifespan. ''Brain Commun''. 2024; '''6''' (2):fcae055
Proxy-analysis of the genetics of cognitive decline in Parkinson's disease through polygenic scores. Description: Faouzi, Johann, et al. Proxy-analysis of the genetics of cognitive decline in Parkinson's disease through polygenic scores. ''NPJ Parkinsons Dis''. 2024 Jan 4; '''10''' (1):8
Radiomic tractometry reveals tract-specific imaging biomarkers in white matter. Description: Neher, Peter, et al. Radiomic tractometry reveals tract-specific imaging biomarkers in white matter. ''Nat Commun''. 2024 Jan 5; '''15''' (1):303
A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models. Description: Hall, Ashley, et al. A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models. ''Sci Rep''. 2024 Jan 8; '''14''' (1):792
Immunological shifts during early-stage Parkinson's disease identified with DNA methylation data on longitudinally collected blood samples. Description: Pike, Steven C, et al. Immunological shifts during early-stage Parkinson's disease identified with DNA methylation data on longitudinally collected blood samples. ''NPJ Parkinsons Dis''. 2024 Jan 11; '''10''' (1):21
Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression. Description: Whittle, Benjamin J, et al. Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression. ''NPJ Parkinsons Dis''. 2024 Jan 20; '''10''' (1):25
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Description: Dorion, Marie-France, et al. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. ''Brain''. 2024 Feb 1; '''147''' (2):427-443
Differences in brain aging between sexes in Parkinson's disease. Description: Beheshti, Iman, et al. Differences in brain aging between sexes in Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 Feb 14; '''10''' (1):35
Deep learning-based BMI inference from structural brain MRI reflects brain alterations following lifestyle intervention. Description: Finkelstein, Ofek, et al. Deep learning-based BMI inference from structural brain MRI reflects brain alterations following lifestyle intervention. ''Hum Brain Mapp''. 2024 Feb 15; '''45''' (3):e26595
Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis. Description: Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis. ''''. 2024 Feb 15; '''10''' (3):e24975
Assessing methylation detection for primary human tissue using Nanopore sequencing. Description: Genner, Rylee, et al. Assessing methylation detection for primary human tissue using Nanopore sequencing. ''bioRxiv''. 2024 Mar 1;
Correlation of slow-wave sleep with motor and nonmotor progression in Parkinson's disease. Description: Chen, Jing, et al. Correlation of slow-wave sleep with motor and nonmotor progression in Parkinson's disease. ''Ann Clin Transl Neurol''. 2024 Mar; '''11''' (3):554-563
Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI. Description: Zhu, Alyssa H, et al. Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI. ''bioRxiv''. 2024 Mar 1;
Machine learning nominates the inositol pathway and novel genes in Parkinson's disease. Description: Yu, Eric, et al. Machine learning nominates the inositol pathway and novel genes in Parkinson's disease. ''Brain''. 2024 Mar 1; '''147''' (3):887-899
Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation. Description: Hollunder, Barbara, et al. Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation. ''Nat Neurosci''. 2024 Mar; '''27''' (3):573-586
Distinctive whole-brain cell types predict tissue damage patterns in thirteen neurodegenerative conditions. Description: Pak, Veronika, et al. Distinctive whole-brain cell types predict tissue damage patterns in thirteen neurodegenerative conditions. ''Elife''. 2024 Mar 21; '''12''':
Automated identification of uncertain cases in deep learning-based classification of dopamine transporter SPECT to improve clinical utility and acceptance. Description: Budenkotte, Thomas, et al. Automated identification of uncertain cases in deep learning-based classification of dopamine transporter SPECT to improve clinical utility and acceptance. ''Eur J Nucl Med Mol Imaging''. 2024 Apr; '''51''' (5):1333-1344
Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants. Description: Jin, Ryota, et al. Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants. ''CPT Pharmacometrics Syst Pharmacol''. 2024 Apr; '''13''' (4):649-659
An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders. Description: Dorion, Marie-France, et al. An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders. ''Mol Neurodegener''. 2024 Apr 5; '''19''' (1):31
A decision support system based on recurrent neural networks to predict medication dosage for patients with Parkinson's disease. Description: Riasi, Atiye, et al. A decision support system based on recurrent neural networks to predict medication dosage for patients with Parkinson's disease. ''Sci Rep''. 2024 Apr 10; '''14''' (1):8424
Lysosomal genes contribute to Parkinson's disease near agriculture with high intensity pesticide use. Description: Ngo, Kathie J, et al. Lysosomal genes contribute to Parkinson's disease near agriculture with high intensity pesticide use. ''NPJ Parkinsons Dis''. 2024 Apr 25; '''10''' (1):87
Longitudinal study investigating the influence of COMT gene polymorphism on cortical thickness changes in Parkinson's disease over four years. Description: Tajerian, Amin. Longitudinal study investigating the influence of COMT gene polymorphism on cortical thickness changes in Parkinson's disease over four years. ''Sci Rep''. 2024 Apr 30; '''14''' (1):9920
Progression subtypes in Parkinson's disease identified by a data-driven multi cohort analysis. Description: Hahnel, Tom, et al. Progression subtypes in Parkinson's disease identified by a data-driven multi cohort analysis. ''NPJ Parkinsons Dis''. 2024 May 2; '''10''' (1):95
Structural underpinnings and long-term effects of resilience in Parkinson's disease. Description: Dzialas, Verena, et al. Structural underpinnings and long-term effects of resilience in Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 May 2; '''10''' (1):94
Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson's disease progression. Description: Frohlich, Alexander, et al. Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson's disease progression. ''Sci Rep''. 2024 May 13; '''14''' (1):10932
Profiling complex repeat expansions in RFC1 in Parkinson's disease. Description: Alvarez Jerez, Pilar, et al. Profiling complex repeat expansions in RFC1 in Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 May 24; '''10''' (1):108
Digital outcome measures from smartwatch data relate to non-motor features of Parkinson's disease. Description: Schalkamp, Ann-Kathrin, et al. Digital outcome measures from smartwatch data relate to non-motor features of Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 May 29; '''10''' (1):110
Are rare heterozygous SYNJ1 variants associated with Parkinson's disease? Description: Senkevich, Konstantin, et al. Are rare heterozygous SYNJ1 variants associated with Parkinson's disease? ''medRxiv''. 2024 Jun 1;
Atrophy patterns in hippocampus and amygdala subregions of depressed patients with Parkinson's disease. Description: Qu, Mingrui, et al. Atrophy patterns in hippocampus and amygdala subregions of depressed patients with Parkinson's disease. ''Brain Imaging Behav''. 2024 Jun; '''18''' (3):475-484
Left corticospinal tract could be a biomarker to identify the dual prodromal LRRK2/GBA mutated Parkinson's disease. Description: Lin, Fabin, et al. Left corticospinal tract could be a biomarker to identify the dual prodromal LRRK2/GBA mutated Parkinson's disease. ''CNS Neurosci Ther''. 2024 Jun; '''30''' (6):e14728
Genome-wide association study of glucocerebrosidase activity modifiers. Description: Somerville, Emma N, et al. Genome-wide association study of glucocerebrosidase activity modifiers. ''Res Sq''. 2024 Jun 7;
Genome-wide determinants of mortality and motor progression in Parkinson's disease. Description: Tan, Manuela M X, et al. Genome-wide determinants of mortality and motor progression in Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 Jun 7; '''10''' (1):113
Unlocking the potential: T1-weighed MRI as a powerful predictor of levodopa response in Parkinson's disease. Description: Yan, Junyi, et al. Unlocking the potential: T1-weighed MRI as a powerful predictor of levodopa response in Parkinson's disease. ''Insights Imaging''. 2024 Jun 9; '''15''' (1):141
DOPA-decarboxylase is elevated in CSF, but not plasma, in prodromal and de novo Parkinson's disease. Description: Appleton, Ellen, et al. DOPA-decarboxylase is elevated in CSF, but not plasma, in prodromal and de novo Parkinson's disease. ''Transl Neurodegener''. 2024 Jun 11; '''13''' (1):31
Neuroimaging epicenters as potential sites of onset of the neuroanatomical pathology in schizophrenia. Description: Jiang, Yuchao, et al. Neuroimaging epicenters as potential sites of onset of the neuroanatomical pathology in schizophrenia. ''Sci Adv''. 2024 Jun 14; '''10''' (24):eadk6063
Understanding the role of cerebellum in early Parkinson's disease: a structural and functional MRI study. Description: Pietracupa, S, et al. Understanding the role of cerebellum in early Parkinson's disease: a structural and functional MRI study. ''NPJ Parkinsons Dis''. 2024 Jun 19; '''10''' (1):119
An improved method for diagnosis of Parkinson's disease using deep learning models enhanced with metaheuristic algorithm. Description: Majhi, Babita, et al. An improved method for diagnosis of Parkinson's disease using deep learning models enhanced with metaheuristic algorithm. ''BMC Med Imaging''. 2024 Jun 24; '''24''' (1):156
Associations of cholinergic system integrity with cognitive decline in GBA1 and LRRK2 mutation carriers. Description: Schumacher, Julia, et al. Associations of cholinergic system integrity with cognitive decline in GBA1 and LRRK2 mutation carriers. ''NPJ Parkinsons Dis''. 2024 Jun 29; '''10''' (1):127
Increased mean diffusivity of the caudal motor SNc identifies patients with REM sleep behaviour disorder and Parkinson's disease. Description: Alushaj, Erind, et al. Increased mean diffusivity of the caudal motor SNc identifies patients with REM sleep behaviour disorder and Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 Jun 29; '''10''' (1):128
Profiling people with Parkinson's disease at risk of cognitive decline: Insights from PPMI and ICICLE-PD data. Description: Pourzinal, Dana, et al. Profiling people with Parkinson's disease at risk of cognitive decline: Insights from PPMI and ICICLE-PD data. ''Alzheimers Dement (Amst)''. 2024 Jul-Sep; '''16''' (3):e12625
Sleep disturbances, cognitive decline, and AD biomarkers alterations in early Parkinson's disease. Description: Zhong, Rui, et al. Sleep disturbances, cognitive decline, and AD biomarkers alterations in early Parkinson's disease. ''Ann Clin Transl Neurol''. 2024 Jul; '''11''' (7):1831-1839
Identification of Parkinson's disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data. Description: Su, Chang, et al. Identification of Parkinson's disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data. ''NPJ Digit Med''. 2024 Jul 9; '''7''' (1):184
Radiomics incorporating deep features for predicting Parkinson's disease in (123)I-Ioflupane SPECT. Description: Jiang, Han, et al. Radiomics incorporating deep features for predicting Parkinson's disease in (123)I-Ioflupane SPECT. ''EJNMMI Phys''. 2024 Jul 10; '''11''' (1):60
LRRK2-Associated Parkinsonism With and Without In Vivo Evidence of Alpha-Synuclein Aggregates. Description: Chahine, Lana M, et al. LRRK2-Associated Parkinsonism With and Without In Vivo Evidence of Alpha-Synuclein Aggregates. ''medRxiv''. 2024 Jul 22;
Parkinson's disease psychosis associated with accelerated multidomain cognitive decline. Description: Pisani, Sara, et al. Parkinson's disease psychosis associated with accelerated multidomain cognitive decline. ''BMJ Ment Health''. 2024 Jul 23; '''27''' (1):1-10
Characterizing a complex CT-rich haplotype in intron 4 of SNCA using large-scale targeted amplicon long-read sequencing. Description: Alvarez Jerez, Pilar, et al. Characterizing a complex CT-rich haplotype in intron 4 of SNCA using large-scale targeted amplicon long-read sequencing. ''NPJ Parkinsons Dis''. 2024 Jul 26; '''10''' (1):136
Motor progression trajectories and risk of mild cognitive impairment in Parkinson's disease: A latent class trajectory model from PPMI cohort. Description: Chen, Xi, et al. Motor progression trajectories and risk of mild cognitive impairment in Parkinson's disease: A latent class trajectory model from PPMI cohort. ''CNS Neurosci Ther''. 2024 Aug; '''30''' (8):e14918
Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease. Description: Zhao, Yibo, et al. Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease. ''NPJ Parkinsons Dis''. 2024 Aug 3; '''10''' (1):144
Lack of genetic evidence for NLRP3 inflammasome involvement in Parkinson's disease pathogenesis. Description: Senkevich, Konstantin, et al. Lack of genetic evidence for NLRP3 inflammasome involvement in Parkinson's disease pathogenesis. ''NPJ Parkinsons Dis''. 2024 Aug 5; '''10''' (1):145
Contrastive machine learning reveals Parkinson's disease specific features associated with disease severity and progression. Description: Zheng, Liping, et al. Contrastive machine learning reveals Parkinson's disease specific features associated with disease severity and progression. ''Commun Biol''. 2024 Aug 7; '''7''' (1):954
Predicting Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data. Description: Venuto, Charles S, et al. Predicting Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data. ''medRxiv''. 2024 Aug 8;
A worldwide study of white matter microstructural alterations in people living with Parkinson's disease. Description: Owens-Walton, Conor, et al. A worldwide study of white matter microstructural alterations in people living with Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 Aug 11; '''10''' (1):151
Loss-of-function variants in ITSN1 confer high risk of Parkinson's disease. Description: Skuladottir, Astros Th, et al. Loss-of-function variants in ITSN1 confer high risk of Parkinson's disease. ''NPJ Parkinsons Dis''. 2024 Aug 15; '''10''' (1):140
MRI subtypes in Parkinson's disease across diverse populations and clustering approaches. Description: Inguanzo, Anna, et al. MRI subtypes in Parkinson's disease across diverse populations and clustering approaches. ''NPJ Parkinsons Dis''. 2024 Aug 16; '''10''' (1):159
Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson's disease. Description: Lu, Qianling, et al. Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson's disease. ''Transl Psychiatry''. 2024 Aug 30; '''14''' (1):347
Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson's disease. Description: Eubanks, Elena, et al. Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson's disease. ''bioRxiv''. 2024 Sep 1;
Multi-modality radiomics of conventional T1 weighted and diffusion tensor imaging for differentiating Parkinson's disease motor subtypes in early-stages. Description: Panahi, Mehdi, et al. Multi-modality radiomics of conventional T1 weighted and diffusion tensor imaging for differentiating Parkinson's disease motor subtypes in early-stages. ''Sci Rep''. 2024 Sep 5; '''14''' (1):20708
Contrastive Graph Pooling for Explainable Classification of Brain Networks. Description: Xu, Jiaxing, et al. Contrastive Graph Pooling for Explainable Classification of Brain Networks. ''ArXiv''. 2024 Sep 6;
Long-Term Dementia Risk in Parkinson Disease. Description: Gallagher, Julia, et al. Long-Term Dementia Risk in Parkinson Disease. ''Neurology''. 2024 Sep 10; '''103''' (5):e209699
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts. Description: Dam, Tien, et al. Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts. ''medRxiv''. 2024 Sep 10;
Language Modeling Screens Parkinson's Disease with Self-reported Questionnaires. Description: Reyes, Diego Machado, et al. Language Modeling Screens Parkinson's Disease with Self-reported Questionnaires. ''medRxiv''. 2024 Sep 24;
Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson's disease: Stage-specific patterns and dopaminergic correlates. Description: He, Chentao, et al. Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson's disease: Stage-specific patterns and dopaminergic correlates. ''Neuroimage Clin''. 2024 Sep 29; '''44''': 103679
Exploratory Analysis of the Association Between Plasma Ceramide Alterations and Cognitive Dysfunction in Parkinson's Disease. Description: Liu, Xu, et al. Exploratory Analysis of the Association Between Plasma Ceramide Alterations and Cognitive Dysfunction in Parkinson's Disease. ''CNS Neurosci Ther''. 2024 Oct; '''30''' (10):e70082
Surface-Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior Disorder. Description: Najafzadeh, Milad, et al. Surface-Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior Disorder. ''Brain Behav''. 2024 Oct; '''14''' (10):e70057
Medication recommendation for Parkinson's disease based on dynamics of symptom progression. Description: Oh, Minjae, et al. Medication recommendation for Parkinson's disease based on dynamics of symptom progression. ''Sci Rep''. 2024 Oct 23; '''14''' (1):25051