The links below are to publications on PubMed referring to Micro-Manager. This list is gathered weekly from PubMed automatically.

Publication/References
Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis.
Description: Holt, Liam J, et al. Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. ''Mol Cell''. 2007 Mar 9; '''25''' (5):689-702
Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.
Description: Slep, Kevin C, et al. Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. ''Mol Cell''. 2007 Sep 21; '''27''' (6):976-91
In vivo visualization of type II plasmid segregation: bacterial actin filaments pushing plasmids.
Description: Campbell, Christopher S, et al. In vivo visualization of type II plasmid segregation: bacterial actin filaments pushing plasmids. ''J Cell Biol''. 2007 Dec 3; '''179''' (5):1059-66
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle.
Description: Goshima, Gohta, et al. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. ''J Cell Biol''. 2008 May 5; '''181''' (3):421-9
Investigating intracellular dynamics of FtsZ cytoskeleton with photoactivation single-molecule tracking.
Description: Niu, Lili, et al. Investigating intracellular dynamics of FtsZ cytoskeleton with photoactivation single-molecule tracking. ''Biophys J''. 2008 Aug; '''95''' (4):2009-16
Imaging the boundaries-innovative tools for microscopy of living cells and real-time imaging.
Description: Rosivatz, Erika. Imaging the boundaries-innovative tools for microscopy of living cells and real-time imaging. ''J Chem Biol''. 2008 Nov; '''1''' (1-4):3-15
Investigating sub-spine actin dynamics in rat hippocampal neurons with super-resolution optical imaging.
Description: Tatavarty, Vedakumar, et al. Investigating sub-spine actin dynamics in rat hippocampal neurons with super-resolution optical imaging. ''PLoS One''. 2009 Nov 9; '''4''' (11):e7724
Automated microscopy for high-content RNAi screening.
Description: Conrad, Christian, et al. Automated microscopy for high-content RNAi screening. ''J Cell Biol''. 2010 Feb 22; '''188''' (4):453-61
Insulin controls the spatial distribution of GLUT4 on the cell surface through regulation of its postfusion dispersal.
Description: Stenkula, Karin G, et al. Insulin controls the spatial distribution of GLUT4 on the cell surface through regulation of its postfusion dispersal. ''Cell Metab''. 2010 Sep 8; '''12''' (3):250-9
Xenopus egg extracts increase dynamics of histone H1 on sperm chromatin.
Description: Freedman, Benjamin S, et al. Xenopus egg extracts increase dynamics of histone H1 on sperm chromatin. ''PLoS One''. 2010 Sep 29; '''5''' (9):
Patronin regulates the microtubule network by protecting microtubule minus ends.
Description: Goodwin, Sarah S, et al. Patronin regulates the microtubule network by protecting microtubule minus ends. ''Cell''. 2010 Oct 15; '''143''' (2):263-74
Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans.
Description: Goldsmith, Andrew D, et al. Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans. ''Neural Dev''. 2010 Dec 1; '''5''': 33
The RHO-1 RhoGTPase modulates fertility and multiple behaviors in adult C. elegans.
Description: McMullan, Rachel, et al. The RHO-1 RhoGTPase modulates fertility and multiple behaviors in adult C. elegans. ''PLoS One''. 2011 Feb 28; '''6''' (2):e17265
Imaging C. elegans embryos using an epifluorescent microscope and open source software.
Description: Verbrugghe, Koen J C, et al. Imaging C. elegans embryos using an epifluorescent microscope and open source software. ''J Vis Exp''. 2011 Mar 24;
Force generation upon T cell receptor engagement.
Description: Husson, Julien, et al. Force generation upon T cell receptor engagement. ''PLoS One''. 2011 May 10; '''6''' (5):e19680
Subcellular protein localization by using a genetically encoded fluorescent amino acid.
Description: Charbon, Godefroid, et al. Subcellular protein localization by using a genetically encoded fluorescent amino acid. ''Chembiochem''. 2011 Aug 16; '''12''' (12):1818-21
First node of Ranvier facilitates high-frequency burst encoding.
Description: Kole, Maarten H P. First node of Ranvier facilitates high-frequency burst encoding. ''Neuron''. 2011 Aug 25; '''71''' (4):671-82
An imbalancing act: gap junctions reduce the backward motor circuit activity to bias C. elegans for forward locomotion.
Description: Kawano, Taizo, et al. An imbalancing act: gap junctions reduce the backward motor circuit activity to bias C. elegans for forward locomotion. ''Neuron''. 2011 Nov 17; '''72''' (4):572-86
Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene.
Description: Kratsios, Paschalis, et al. Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene. ''Nat Neurosci''. 2011 Nov 27; '''15''' (2):205-14
Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.
Description: Haynes, Jennifer, et al. Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression. ''Mol Biol Cell''. 2011 Dec; '''22''' (24):4750-64
Katanin contributes to interspecies spindle length scaling in Xenopus.
Description: Loughlin, Rose, et al. Katanin contributes to interspecies spindle length scaling in Xenopus. ''Cell''. 2011 Dec 9; '''147''' (6):1397-407
Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels.
Description: Fallica, Brian, et al. Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels. ''PLoS One''. 2012; '''7''' (10):e48024
Antibiotic transport in resistant bacteria: synchrotron UV fluorescence microscopy to determine antibiotic accumulation with single cell resolution.
Description: Kascakova, Slavka, et al. Antibiotic transport in resistant bacteria: synchrotron UV fluorescence microscopy to determine antibiotic accumulation with single cell resolution. ''PLoS One''. 2012; '''7''' (6):e38624
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis.
Description: Barkan, Rachel, et al. Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis. ''Mol Biol Cell''. 2012 Feb; '''23''' (4):543-52
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1.
Description: Woo, Stephanie, et al. Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. ''J Cell Biol''. 2012 Sep 3; '''198''' (5):941-52
Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration.
Description: Ghosh-Roy, Anindya, et al. Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration. ''Dev Cell''. 2012 Oct 16; '''23''' (4):716-28
Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform.
Description: Yan, Dong, et al. Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform. ''Neuron''. 2012 Nov 8; '''76''' (3):534-48
Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin.
Description: Li, Wenjing, et al. Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin. ''J Cell Biol''. 2012 Nov 26; '''199''' (5):849-62
Calcium dynamics in root cells of Arabidopsis thaliana visualized with selective plane illumination microscopy.
Description: Costa, Alex, et al. Calcium dynamics in root cells of Arabidopsis thaliana visualized with selective plane illumination microscopy. ''PLoS One''. 2013; '''8''' (10):e75646
Chlamydia induces anchorage independence in 3T3 cells and detrimental cytological defects in an infection model.
Description: Knowlton, Andrea E, et al. Chlamydia induces anchorage independence in 3T3 cells and detrimental cytological defects in an infection model. ''PLoS One''. 2013; '''8''' (1):e54022
Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G(2) delay and mitotic defects.
Description: Prystowsky, Michael, et al. Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G(2) delay and mitotic defects. ''Sci Rep''. 2013; '''3''': 2640
Insulin regulates Glut4 confinement in plasma membrane clusters in adipose cells.
Description: Lizunov, Vladimir A, et al. Insulin regulates Glut4 confinement in plasma membrane clusters in adipose cells. ''PLoS One''. 2013; '''8''' (3):e57559
Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster.
Description: Crivat, Georgeta, et al. Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster. ''PLoS One''. 2013; '''8''' (11):e77953
Polymicrobial infection with major periodontal pathogens induced periodontal disease and aortic atherosclerosis in hyperlipidemic ApoE(null) mice.
Description: Rivera, Mercedes F, et al. Polymicrobial infection with major periodontal pathogens induced periodontal disease and aortic atherosclerosis in hyperlipidemic ApoE(null) mice. ''PLoS One''. 2013; '''8''' (2):e57178
An essential and NSF independent role for alpha-SNAP in store-operated calcium entry.
Description: Miao, Yong, et al. An essential and NSF independent role for alpha-SNAP in store-operated calcium entry. ''Elife''. 2013 Jul 16; '''2''': e00802
CCM1-ICAP-1 complex controls beta1 integrin-dependent endothelial contractility and fibronectin remodeling.
Description: Faurobert, Eva, et al. CCM1-ICAP-1 complex controls beta1 integrin-dependent endothelial contractility and fibronectin remodeling. ''J Cell Biol''. 2013 Aug 5; '''202''' (3):545-61
Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones.
Description: Yang, Qing, et al. Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones. ''Mol Biol Cell''. 2013 Oct; '''24''' (19):3097-114
Efficient single-cell transgene induction in Caenorhabditis elegans using a pulsed infrared laser.
Description: Churgin, Matthew A, et al. Efficient single-cell transgene induction in Caenorhabditis elegans using a pulsed infrared laser. ''G3 (Bethesda)''. 2013 Oct 3; '''3''' (10):1827-32
A bidirectional circuit switch reroutes pheromone signals in male and female brains.
Description: Kohl, Johannes, et al. A bidirectional circuit switch reroutes pheromone signals in male and female brains. ''Cell''. 2013 Dec 19; '''155''' (7):1610-23
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.
Description: Schweizer, Nina, et al. Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis. ''J Cell Biol''. 2013 Dec 23; '''203''' (6):883-93
Active invasion of oral and aortic tissues by Porphyromonas gingivalis in mice causally links periodontitis and atherosclerosis.
Description: Velsko, Irina M, et al. Active invasion of oral and aortic tissues by Porphyromonas gingivalis in mice causally links periodontitis and atherosclerosis. ''PLoS One''. 2014; '''9''' (5):e97811
A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila.
Description: Masuda-Nakagawa, Liria M, et al. A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila. ''Front Neural Circuits''. 2014; '''8''': 35
Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rgammanull mice.
Description: Xiao, Fang, et al. Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rgammanull mice. ''PLoS One''. 2014; '''9''' (3):e90387
Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking.
Description: Vermehren-Schmaedick, Anke, et al. Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking. ''PLoS One''. 2014; '''9''' (4):e95113
Multinucleation during C. trachomatis infections is caused by the contribution of two effector pathways.
Description: Brown, Heather M, et al. Multinucleation during C. trachomatis infections is caused by the contribution of two effector pathways. ''PLoS One''. 2014; '''9''' (6):e100763
Multiplex detection of homo- and heterodimerization of g protein-coupled receptors by proximity biotinylation.
Description: Steel, Elisabeth, et al. Multiplex detection of homo- and heterodimerization of g protein-coupled receptors by proximity biotinylation. ''PLoS One''. 2014; '''9''' (4):e93646
OpenComet: an automated tool for comet assay image analysis.
Description: Gyori, Benjamin M, et al. OpenComet: an automated tool for comet assay image analysis. ''Redox Biol''. 2014; '''2''': 457-65
Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors.
Description: Knogler, Laura D, et al. Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors. ''Front Neural Circuits''. 2014; '''8''': 121
G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis.
Description: Stevenson, N L, et al. G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis. ''J Thromb Haemost''. 2014 Feb; '''12''' (2):261-272
Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes.
Description: Smith, Alex J, et al. Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes. ''J Cell Biol''. 2014 Feb 17; '''204''' (4):559-73
Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.
Description: Ballister, Edward R, et al. Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. ''J Cell Biol''. 2014 Mar 17; '''204''' (6):901-8
An operon of three transcriptional regulators controls horizontal gene transfer of the integrative and conjugative element ICEclc in Pseudomonas knackmussii B13.
Description: Pradervand, Nicolas, et al. An operon of three transcriptional regulators controls horizontal gene transfer of the integrative and conjugative element ICEclc in Pseudomonas knackmussii B13. ''PLoS Genet''. 2014 Jun; '''10''' (6):e1004441
High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor.
Description: St-Pierre, Francois, et al. High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor. ''Nat Neurosci''. 2014 Jun; '''17''' (6):884-9
High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation.
Description: Currie, Erin, et al. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. ''J Lipid Res''. 2014 Jul; '''55''' (7):1465-77
Temporal and spatial temperature measurement in insulator-based dielectrophoretic devices.
Description: Nakano, Asuka, et al. Temporal and spatial temperature measurement in insulator-based dielectrophoretic devices. ''Anal Chem''. 2014 Jul 1; '''86''' (13):6516-24
TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts.
Description: Helmke, Kara J, et al. TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts. ''J Cell Biol''. 2014 Aug 4; '''206''' (3):385-93
Bioinspired microfluidic assay for in vitro modeling of leukocyte-endothelium interactions.
Description: Lamberti, Giuseppina, et al. Bioinspired microfluidic assay for in vitro modeling of leukocyte-endothelium interactions. ''Anal Chem''. 2014 Aug 19; '''86''' (16):8344-51
UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity.
Description: Wang, Zheng, et al. UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity. ''J Cell Biol''. 2014 Sep 1; '''206''' (5):619-33
Conditional knockouts generated by engineered CRISPR-Cas9 endonuclease reveal the roles of coronin in C. elegans neural development.
Description: Shen, Zhongfu, et al. Conditional knockouts generated by engineered CRISPR-Cas9 endonuclease reveal the roles of coronin in C. elegans neural development. ''Dev Cell''. 2014 Sep 8; '''30''' (5):625-36
Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia.
Description: Tajon, Cheryl A, et al. Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia. ''ACS Nano''. 2014 Sep 23; '''8''' (9):9199-208
The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport.
Description: Zheng, Qun, et al. The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport. ''PLoS Genet''. 2014 Oct; '''10''' (10):e1004644
LKB1 and AMPK differentially regulate pancreatic beta-cell identity.
Description: Kone, Marina, et al. LKB1 and AMPK differentially regulate pancreatic beta-cell identity. ''FASEB J''. 2014 Nov; '''28''' (11):4972-85
Rapid measurement of molecular transport and interaction inside living cells using single plane illumination.
Description: Hedde, Per Niklas, et al. Rapid measurement of molecular transport and interaction inside living cells using single plane illumination. ''Sci Rep''. 2014 Nov 14; '''4''': 7048
Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing.
Description: Denoth-Lippuner, Annina, et al. Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing. ''Elife''. 2014 Nov 17; '''3''':
Single-molecule imaging reveals that small amyloid-beta1-42 oligomers interact with the cellular prion protein (PrP(C)).
Description: Ganzinger, Kristina A, et al. Single-molecule imaging reveals that small amyloid-beta1-42 oligomers interact with the cellular prion protein (PrP(C)). ''Chembiochem''. 2014 Nov 24; '''15''' (17):2515-21
High resolution surface plasmon resonance imaging for single cells.
Description: Peterson, Alexander W, et al. High resolution surface plasmon resonance imaging for single cells. ''BMC Cell Biol''. 2014 Dec 1; '''15''': 35
Membrane tethering by the atlastin GTPase depends on GTP hydrolysis but not on forming the cross-over configuration.
Description: Saini, Simran G, et al. Membrane tethering by the atlastin GTPase depends on GTP hydrolysis but not on forming the cross-over configuration. ''Mol Biol Cell''. 2014 Dec 1; '''25''' (24):3942-53
Controlled growth of filamentous fatty acid vesicles under flow.
Description: Hentrich, Christian, et al. Controlled growth of filamentous fatty acid vesicles under flow. ''Langmuir''. 2014 Dec 16; '''30''' (49):14916-25
Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ.
Description: Vischer, Norbert O E, et al. Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ. ''Front Microbiol''. 2015; '''6''': 586
Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Markers with an Atheroprotective Immune Response in ApoE(null) Mice.
Description: Velsko, Irina M, et al. Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Markers with an Atheroprotective Immune Response in ApoE(null) Mice. ''PLoS One''. 2015; '''10''' (6):e0129795
NKp46 Clusters at the Immune Synapse and Regulates NK Cell Polarization.
Description: Hadad, Uzi, et al. NKp46 Clusters at the Immune Synapse and Regulates NK Cell Polarization. ''Front Immunol''. 2015; '''6''': 495
Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway.
Description: Sartorel, Elodie, et al. Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway. ''Mol Biol Cell''. 2015 Jan 1; '''26''' (1):134-50
RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization.
Description: Zou, Wei, et al. RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization. ''PLoS Genet''. 2015; '''11''' (9):e1005484
Reed-Sternberg cells form by abscission failure in the presence of functional Aurora B kinase.
Description: Xavier de Carvalho, Ana, et al. Reed-Sternberg cells form by abscission failure in the presence of functional Aurora B kinase. ''PLoS One''. 2015; '''10''' (5):e0124629
Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.
Description: Placencio, Veronica R, et al. Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. ''PLoS One''. 2015; '''10''' (7):e0133786
Spinning-Spot Shadowless TIRF Microscopy.
Description: Ellefsen, Kyle L, et al. Spinning-Spot Shadowless TIRF Microscopy. ''PLoS One''. 2015; '''10''' (8):e0136055
A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.
Description: Butler, Victoria J, et al. A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans. ''J R Soc Interface''. 2015 Jan 6; '''12''' (102):20140963
From intracellular signaling to population oscillations: bridging size- and time-scales in collective behavior.
Description: Sgro, Allyson E, et al. From intracellular signaling to population oscillations: bridging size- and time-scales in collective behavior. ''Mol Syst Biol''. 2015 Jan 23; '''11''' (1):779
A general method to improve fluorophores for live-cell and single-molecule microscopy.
Description: Grimm, Jonathan B, et al. A general method to improve fluorophores for live-cell and single-molecule microscopy. ''Nat Methods''. 2015 Mar; '''12''' (3):244-50, 3 p following 250
Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange.
Description: Ding, Yidan, et al. Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange. ''Nat Methods''. 2015 Mar; '''12''' (3):195-8
Upward synaptic scaling is dependent on neurotransmission rather than spiking.
Description: Fong, Ming-fai, et al. Upward synaptic scaling is dependent on neurotransmission rather than spiking. ''Nat Commun''. 2015 Mar 9; '''6''': 6339
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
Description: Blohberger, J, et al. Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions? ''Cell Death Dis''. 2015 Mar 12; '''6''': e1685
Somatic CRISPR-Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia.
Description: Li, Wenjing, et al. Somatic CRISPR-Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia. ''J Cell Biol''. 2015 Mar 16; '''208''' (6):683-92
Subrepellent doses of Slit1 promote Netrin-1 chemotactic responses in subsets of axons.
Description: Dupin, Isabelle, et al. Subrepellent doses of Slit1 promote Netrin-1 chemotactic responses in subsets of axons. ''Neural Dev''. 2015 Mar 20; '''10''': 5
TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus.
Description: Feetham, C H, et al. TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus. ''Br J Pharmacol''. 2015 Apr; '''172''' (7):1753-68
Inefficient clearance of myelin debris by microglia impairs remyelinating processes.
Description: Lampron, Antoine, et al. Inefficient clearance of myelin debris by microglia impairs remyelinating processes. ''J Exp Med''. 2015 Apr 6; '''212''' (4):481-95
Role for electrical synapses in shaping the output of coupled peptidergic neurons from Lymnaea.
Description: Beekharry, Christopher C, et al. Role for electrical synapses in shaping the output of coupled peptidergic neurons from Lymnaea. ''Brain Res''. 2015 Apr 7; '''1603''': 8-21
The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO(2).
Description: Ruffault, Pierre-Louis, et al. The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO(2). ''Elife''. 2015 Apr 13; '''4''':
Anillin Regulates Neuronal Migration and Neurite Growth by Linking RhoG to the Actin Cytoskeleton.
Description: Tian, Dong, et al. Anillin Regulates Neuronal Migration and Neurite Growth by Linking RhoG to the Actin Cytoskeleton. ''Curr Biol''. 2015 May 4; '''25''' (9):1135-45
Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division.
Description: Gray, Andrew N, et al. Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division. ''Elife''. 2015 May 7; '''4''':
Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression.
Description: van Zon, Jeroen Sebastiaan, et al. Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression. ''Nat Commun''. 2015 May 11; '''6''': 7053
Molecular architecture of native fibronectin fibrils.
Description: Fruh, Susanna Maria, et al. Molecular architecture of native fibronectin fibrils. ''Nat Commun''. 2015 Jun 4; '''6''': 7275
Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction.
Description: Abdallah, Bahige G, et al. Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction. ''Struct Dyn''. 2015 Jul; '''2''' (4):041719
Rapid access to phospholipid analogs using thiol-yne chemistry.
Description: Zhou, Cun Yu, et al. Rapid access to phospholipid analogs using thiol-yne chemistry. ''Chem Sci''. 2015 Jul 1; '''6''' (7):4365-4372
Mechanical properties of a primary cilium as measured by resonant oscillation.
Description: Resnick, Andrew. Mechanical properties of a primary cilium as measured by resonant oscillation. ''Biophys J''. 2015 Jul 7; '''109''' (1):18-25
Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics.
Description: van der Ploeg, Rene, et al. Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics. ''Int J Mol Sci''. 2015 Jul 31; '''16''' (8):17637-54
Regulation of mRNA translation during mitosis.
Description: Tanenbaum, Marvin E, et al. Regulation of mRNA translation during mitosis. ''Elife''. 2015 Aug 25; '''4''':
TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
Description: Watanabe, Takashi, et al. TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. ''J Cell Biol''. 2015 Aug 31; '''210''' (5):737-51
The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis.
Description: Donaldson, David S, et al. The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis. ''J Virol''. 2015 Sep; '''89''' (18):9532-47
Tunable and reversible drug control of protein production via a self-excising degron.
Description: Chung, Hokyung K, et al. Tunable and reversible drug control of protein production via a self-excising degron. ''Nat Chem Biol''. 2015 Sep; '''11''' (9):713-20
Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp.
Description: Gao, Shiqiang, et al. Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp. ''Nat Commun''. 2015 Sep 8; '''6''': 8046
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Description: Min, Sang-Won, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. ''Nat Med''. 2015 Oct; '''21''' (10):1154-62
Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors.
Description: Bai, Fang, et al. Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors. ''Sci Rep''. 2015 Oct 9; '''5''': 15014
Fission yeast kinesin-8 controls chromosome congression independently of oscillations.
Description: Mary, Hadrien, et al. Fission yeast kinesin-8 controls chromosome congression independently of oscillations. ''J Cell Sci''. 2015 Oct 15; '''128''' (20):3720-30
Combinatorial gene regulation by modulation of relative pulse timing.
Description: Lin, Yihan, et al. Combinatorial gene regulation by modulation of relative pulse timing. ''Nature''. 2015 Nov 5; '''527''' (7576):54-8
Two-dimensional slither swimming of sperm within a micrometre of a surface.
Description: Nosrati, Reza, et al. Two-dimensional slither swimming of sperm within a micrometre of a surface. ''Nat Commun''. 2015 Nov 10; '''6''': 8703
Ephrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation.
Description: Stark, Danny A, et al. Ephrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation. ''J Cell Biol''. 2015 Dec 7; '''211''' (5):1077-91
Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle.
Description: Ito, Ami, et al. Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle. ''J Cell Biol''. 2015 Dec 7; '''211''' (5):999-1009
Annexin A1 Deficiency does not Affect Myofiber Repair but Delays Regeneration of Injured Muscles.
Description: Leikina, Evgenia, et al. Annexin A1 Deficiency does not Affect Myofiber Repair but Delays Regeneration of Injured Muscles. ''Sci Rep''. 2015 Dec 15; '''5''': 18246
Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections.
Description: Smith, Alex J, et al. Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections. ''Biophys J''. 2015 Dec 15; '''109''' (12):2511-2522
Non-Cytotoxic Quantum Dot-Chitosan Nanogel Biosensing Probe for Potential Cancer Targeting Agent.
Description: Maxwell, Tyler, et al. Non-Cytotoxic Quantum Dot-Chitosan Nanogel Biosensing Probe for Potential Cancer Targeting Agent. ''Nanomaterials (Basel)''. 2015 Dec 18; '''5''' (4):2359-2379
A cellular and regulatory map of the cholinergic nervous system of C. elegans.
Description: Pereira, Laura, et al. A cellular and regulatory map of the cholinergic nervous system of C. elegans. ''Elife''. 2015 Dec 25; '''4''':
Disruption of the Golgi protein Otg1 gene causes defective hormone secretion and aberrant glucose homeostasis in mice.
Description: Wang, Guangxue, et al. Disruption of the Golgi protein Otg1 gene causes defective hormone secretion and aberrant glucose homeostasis in mice. ''Cell Biosci''. 2016; '''6''': 41
Forced Trefoil Factor Family Peptide 3 (TFF3) Expression Reduces Growth, Viability, and Tumorigenicity of Human Retinoblastoma Cell Lines.
Description: Grosse-Kreul, Jan, et al. Forced Trefoil Factor Family Peptide 3 (TFF3) Expression Reduces Growth, Viability, and Tumorigenicity of Human Retinoblastoma Cell Lines. ''PLoS One''. 2016; '''11''' (9):e0163025
Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry.
Description: Huang, He, et al. Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry. ''Mol Cell Proteomics''. 2016 Jan; '''15''' (1):201-17
Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response.
Description: Marks, Ellen, et al. Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response. ''Front Immunol''. 2016; '''7''': 643
The Vitamin B1 and B12 Required by the Marine Dinoflagellate Lingulodinium polyedrum Can be Provided by its Associated Bacterial Community in Culture.
Description: Cruz-Lopez, Ricardo, et al. The Vitamin B1 and B12 Required by the Marine Dinoflagellate Lingulodinium polyedrum Can be Provided by its Associated Bacterial Community in Culture. ''Front Microbiol''. 2016; '''7''': 560
Multistep assembly of DNA condensation clusters by SMC.
Description: Kim, HyeongJun, et al. Multistep assembly of DNA condensation clusters by SMC. ''Nat Commun''. 2016 Jan 4; '''7''': 10200
Purification, Visualization, and Molecular Signature of Neural Stem Cells.
Description: Yu, Yuan Hong, et al. Purification, Visualization, and Molecular Signature of Neural Stem Cells. ''Stem Cells Dev''. 2016 Jan 15; '''25''' (2):189-201
The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts.
Description: Rinaldi, Arlie J, et al. The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts. ''Nat Commun''. 2016 Jan 19; '''7''': 8976
Currents through Hv1 channels deplete protons in their vicinity.
Description: De-la-Rosa, Victor, et al. Currents through Hv1 channels deplete protons in their vicinity. ''J Gen Physiol''. 2016 Feb; '''147''' (2):127-36
Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting.
Description: Bajar, Bryce T, et al. Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting. ''Sci Rep''. 2016 Feb 16; '''6''': 20889
Blue Light Modulates Murine Microglial Gene Expression in the Absence of Optogenetic Protein Expression.
Description: Cheng, Kevin P, et al. Blue Light Modulates Murine Microglial Gene Expression in the Absence of Optogenetic Protein Expression. ''Sci Rep''. 2016 Feb 17; '''6''': 21172
Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging.
Description: Li, Yan, et al. Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging. ''Sci Rep''. 2016 Mar 1; '''6''': 22129
Versatile protein tagging in cells with split fluorescent protein.
Description: Kamiyama, Daichi, et al. Versatile protein tagging in cells with split fluorescent protein. ''Nat Commun''. 2016 Mar 18; '''7''': 11046
Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics.
Description: Sarkar, Aniruddh, et al. Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics. ''Sci Rep''. 2016 Mar 30; '''6''': 23589
Rem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia.
Description: Liput, Daniel J, et al. Rem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia. ''Sci Rep''. 2016 Apr 27; '''6''': 25137
Alteration of AMPA Receptor-Mediated Synaptic Transmission by Alexa Fluor 488 and 594 in Cerebellar Stellate Cells.
Description: Maroteaux, Matthieu, et al. Alteration of AMPA Receptor-Mediated Synaptic Transmission by Alexa Fluor 488 and 594 in Cerebellar Stellate Cells. ''eNeuro''. 2016 May-Jun; '''3''' (3):
Arabidopsis FIM5 decorates apical actin filaments and regulates their organization in the pollen tube.
Description: Zhang, Meng, et al. Arabidopsis FIM5 decorates apical actin filaments and regulates their organization in the pollen tube. ''J Exp Bot''. 2016 May; '''67''' (11):3407-17
Differential Phosphorylation Provides a Switch to Control How alpha-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae.
Description: Alvaro, Christopher G, et al. Differential Phosphorylation Provides a Switch to Control How alpha-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae. ''Genetics''. 2016 May; '''203''' (1):299-317
Phosphorylation of beta-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis.
Description: Ori-McKenney, Kassandra M, et al. Phosphorylation of beta-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. ''Neuron''. 2016 May 4; '''90''' (3):551-63
Dynamics of Translation of Single mRNA Molecules In Vivo.
Description: Yan, Xiaowei, et al. Dynamics of Translation of Single mRNA Molecules In Vivo. ''Cell''. 2016 May 5; '''165''' (4):976-89
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.
Description: Okumus, Burak, et al. Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells. ''Nat Commun''. 2016 May 18; '''7''': 11641
A method to rapidly create protein aggregates in living cells.
Description: Miyazaki, Yusuke, et al. A method to rapidly create protein aggregates in living cells. ''Nat Commun''. 2016 May 27; '''7''': 11689
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Description: Zhao, Bo, et al. Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. ''Elife''. 2016 Jun 8; '''5''':
Quantitative imaging of lipids in live mouse oocytes and early embryos using CARS microscopy.
Description: Bradley, Josephine, et al. Quantitative imaging of lipids in live mouse oocytes and early embryos using CARS microscopy. ''Development''. 2016 Jun 15; '''143''' (12):2238-47
Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting.
Description: Jacob, Thomas, et al. Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting. ''Sci Rep''. 2016 Jun 20; '''6''': 28163
Light-sheet microscopy for everyone? Experience of building an OpenSPIM to study flatworm development.
Description: Girstmair, Johannes, et al. Light-sheet microscopy for everyone? Experience of building an OpenSPIM to study flatworm development. ''BMC Dev Biol''. 2016 Jun 30; '''16''' (1):22
A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo.
Description: Chu, Jun, et al. A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo. ''Nat Biotechnol''. 2016 Jul; '''34''' (7):760-7
The Integrated Role of Wnt/beta-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics.
Description: Vargas, Diego A, et al. The Integrated Role of Wnt/beta-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics. ''PLoS Comput Biol''. 2016 Jul; '''12''' (7):e1005007
mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence.
Description: Finnigan, Gregory C, et al. mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence. ''G3 (Bethesda)''. 2016 Jul 7; '''6''' (7):2147-56
Methodology for Quantitative Characterization of Fluorophore Photoswitching to Predict Superresolution Microscopy Image Quality.
Description: Bittel, Amy M, et al. Methodology for Quantitative Characterization of Fluorophore Photoswitching to Predict Superresolution Microscopy Image Quality. ''Sci Rep''. 2016 Jul 14; '''6''': 29687
An antibody toolkit for the study of membrane traffic in Drosophila melanogaster.
Description: Riedel, Falko, et al. An antibody toolkit for the study of membrane traffic in Drosophila melanogaster. ''Biol Open''. 2016 Jul 15; '''5''' (7):987-92
Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae.
Description: Finnigan, Gregory C, et al. Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae. ''Mol Biol Cell''. 2016 Jul 15; '''27''' (14):2213-33
Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system.
Description: Finnigan, Gregory C, et al. Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system. ''Mol Biol Cell''. 2016 Sep 1; '''27''' (17):2708-25
Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity.
Description: Joost, Simon, et al. Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity. ''Cell Syst''. 2016 Sep 28; '''3''' (3):221-237.e9
Thirst neurons anticipate the homeostatic consequences of eating and drinking.
Description: Zimmerman, Christopher A, et al. Thirst neurons anticipate the homeostatic consequences of eating and drinking. ''Nature''. 2016 Sep 29; '''537''' (7622):680-684
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel.
Description: Upadhyay, Awani, et al. Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel. ''Nat Commun''. 2016 Oct 12; '''7''': 13135
A cellular and regulatory map of the GABAergic nervous system of C. elegans.
Description: Gendrel, Marie, et al. A cellular and regulatory map of the GABAergic nervous system of C. elegans. ''Elife''. 2016 Oct 14; '''5''':
Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread.
Description: Lamason, Rebecca L, et al. Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread. ''Cell''. 2016 Oct 20; '''167''' (3):670-683.e10
Super-resolution imaging of multiple cells by optimised flat-field epi-illumination.
Description: Douglass, Kyle M, et al. Super-resolution imaging of multiple cells by optimised flat-field epi-illumination. ''Nat Photonics''. 2016 Nov; '''10''' (11):705-708
GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe.
Description: Piedra, Felipe-Andres, et al. GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe. ''Mol Biol Cell''. 2016 Nov 7; '''27''' (22):3515-3525
Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.
Description: Donaldson, David S, et al. Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility. ''PLoS Pathog''. 2016 Dec; '''12''' (12):e1006075
Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs.
Description: Varandas, Katherine C, et al. Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs. ''Curr Biol''. 2016 Dec 5; '''26''' (23):3129-3142
Multiple signal classification algorithm for super-resolution fluorescence microscopy.
Description: Agarwal, Krishna, et al. Multiple signal classification algorithm for super-resolution fluorescence microscopy. ''Nat Commun''. 2016 Dec 9; '''7''': 13752
Distinct cellular states determine calcium signaling response.
Description: Yao, Jason, et al. Distinct cellular states determine calcium signaling response. ''Mol Syst Biol''. 2016 Dec 15; '''12''' (12):894
Analysis of Septin Reorganization at Cytokinesis Using Polarized Fluorescence Microscopy.
Description: McQuilken, Molly, et al. Analysis of Septin Reorganization at Cytokinesis Using Polarized Fluorescence Microscopy. ''Front Cell Dev Biol''. 2017; '''5''': 42
Characterization of kinesin switch I mutations that cause hereditary spastic paraplegia.
Description: Jennings, Scott, et al. Characterization of kinesin switch I mutations that cause hereditary spastic paraplegia. ''PLoS One''. 2017; '''12''' (7):e0180353
Engineering of mCherry variants with long Stokes shift, red-shifted fluorescence, and low cytotoxicity.
Description: Shen, Yi, et al. Engineering of mCherry variants with long Stokes shift, red-shifted fluorescence, and low cytotoxicity. ''PLoS One''. 2017; '''12''' (2):e0171257
Evaluation of quantum dot conjugated antibodies for immunofluorescent labelling of cellular targets.
Description: Francis, Jennifer E, et al. Evaluation of quantum dot conjugated antibodies for immunofluorescent labelling of cellular targets. ''Beilstein J Nanotechnol''. 2017; '''8''': 1238-1249
The Replisomes Remain Spatially Proximal throughout the Cell Cycle in Bacteria.
Description: Mangiameli, Sarah M, et al. The Replisomes Remain Spatially Proximal throughout the Cell Cycle in Bacteria. ''PLoS Genet''. 2017 Jan; '''13''' (1):e1006582
Vascularization and innervation of slits within polydimethylsiloxane sheets in the subcutaneous space of athymic nude mice.
Description: Gurlin, Rachel E, et al. Vascularization and innervation of slits within polydimethylsiloxane sheets in the subcutaneous space of athymic nude mice. ''J Tissue Eng''. 2017 Jan-Dec; '''8''': 2041731417691645
Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast.
Description: Fox, Colette, et al. Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast. ''Wellcome Open Res''. 2017 Jan 5; '''2''': 2
Transcription leads to pervasive replisome instability in bacteria.
Description: Mangiameli, Sarah M, et al. Transcription leads to pervasive replisome instability in bacteria. ''Elife''. 2017 Jan 16; '''6''':
c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium.
Description: Sehgal, Anuj, et al. c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium. ''Immunobiology''. 2017 Feb; '''222''' (2):316-326
Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential for Endoplasmic Reticulum to Outer Mitochondrial Membrane Protein Transport.
Description: Salka, Kyle, et al. Superresolution Imaging Identifies That Conventional Trafficking Pathways Are Not Essential for Endoplasmic Reticulum to Outer Mitochondrial Membrane Protein Transport. ''Sci Rep''. 2017 Feb 2; '''7''' (1):16
Differential Routing of Mindbomb1 via Centriolar Satellites Regulates Asymmetric Divisions of Neural Progenitors.
Description: Tozer, Samuel, et al. Differential Routing of Mindbomb1 via Centriolar Satellites Regulates Asymmetric Divisions of Neural Progenitors. ''Neuron''. 2017 Feb 8; '''93''' (3):542-551.e4
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells.
Description: Sternfeld, Matthew J, et al. Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells. ''Elife''. 2017 Feb 14; '''6''':
Combination of ruthenium(II)-arene complex [Ru(eta(6)-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity.
Description: Berndsen, Robert H, et al. Combination of ruthenium(II)-arene complex [Ru(eta(6)-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity. ''Sci Rep''. 2017 Feb 22; '''7''': 43005
Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Description: Badgandi, Hemant B, et al. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. ''J Cell Biol''. 2017 Mar 6; '''216''' (3):743-760
Application of an E. coli signal sequence as a versatile inclusion body tag.
Description: Jong, Wouter S P, et al. Application of an E. coli signal sequence as a versatile inclusion body tag. ''Microb Cell Fact''. 2017 Mar 21; '''16''' (1):50
Tracking Multiple Genomic Elements Using Correlative CRISPR Imaging and Sequential DNA FISH.
Description: Guan, Juan, et al. Tracking Multiple Genomic Elements Using Correlative CRISPR Imaging and Sequential DNA FISH. ''Biophys J''. 2017 Mar 28; '''112''' (6):1077-1084
Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion.
Description: Yang, Yihong, et al. Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion. ''Dev Cell''. 2017 Apr 10; '''41''' (1):107-120.e4
Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function.
Description: Weinberger, Simon, et al. Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function. ''Elife''. 2017 Apr 13; '''6''':
Lissencephaly-1 is a context-dependent regulator of the human dynein complex.
Description: Baumbach, Janina, et al. Lissencephaly-1 is a context-dependent regulator of the human dynein complex. ''Elife''. 2017 Apr 13; '''6''':
A coordinated DNA damage response promotes adult quiescent neural stem cell activation.
Description: Barazzuol, Lara, et al. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. ''PLoS Biol''. 2017 May; '''15''' (5):e2001264
The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion.
Description: Winsor, James, et al. The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion. ''J Cell Biol''. 2017 May 1; '''216''' (5):1321-1335
Integrated single- and two-photon light sheet microscopy using accelerating beams.
Description: Piksarv, Peeter, et al. Integrated single- and two-photon light sheet microscopy using accelerating beams. ''Sci Rep''. 2017 May 3; '''7''' (1):1435
Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia.
Description: Yi, Peishan, et al. Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia. ''Curr Biol''. 2017 May 22; '''27''' (10):1448-1461.e7
Divergent extremes but convergent recovery of bacterial and archaeal soil communities to an ongoing subterranean coal mine fire.
Description: Lee, Sang-Hoon, et al. Divergent extremes but convergent recovery of bacterial and archaeal soil communities to an ongoing subterranean coal mine fire. ''ISME J''. 2017 Jun; '''11''' (6):1447-1459
WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility.
Description: Fritz-Laylin, Lillian K, et al. WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility. ''J Cell Biol''. 2017 Jun 5; '''216''' (6):1673-1688
Semen amyloids participate in spermatozoa selection and clearance.
Description: Roan, Nadia R, et al. Semen amyloids participate in spermatozoa selection and clearance. ''Elife''. 2017 Jun 27; '''6''':
Functional selectivity of GPCR-directed drug action through location bias.
Description: Irannejad, Roshanak, et al. Functional selectivity of GPCR-directed drug action through location bias. ''Nat Chem Biol''. 2017 Jul; '''13''' (7):799-806
Proteins mediating DNA loops effectively block transcription.
Description: Voros, Zsuzsanna, et al. Proteins mediating DNA loops effectively block transcription. ''Protein Sci''. 2017 Jul; '''26''' (7):1427-1438
Salmonella enterica serovar-specific transcriptional reprogramming of infected cells.
Description: Hannemann, Sebastian, et al. Salmonella enterica serovar-specific transcriptional reprogramming of infected cells. ''PLoS Pathog''. 2017 Jul; '''13''' (7):e1006532
RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2.
Description: Chen, Yu-Ju, et al. RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2. ''J Cell Biol''. 2017 Jul 3; '''216''' (7):2011-2025
An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons.
Description: Kratsios, Paschalis, et al. An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons. ''Elife''. 2017 Jul 5; '''6''':
Ammonium chloride alters neuronal excitability and synaptic vesicle release.
Description: Lazarenko, Roman M, et al. Ammonium chloride alters neuronal excitability and synaptic vesicle release. ''Sci Rep''. 2017 Jul 11; '''7''' (1):5061
Neurite elongation is highly correlated with bulk forward translocation of microtubules.
Description: Athamneh, Ahmad I M, et al. Neurite elongation is highly correlated with bulk forward translocation of microtubules. ''Sci Rep''. 2017 Aug 4; '''7''' (1):7292
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z beta as an Essential Regulator of Spindle Orientation.
Description: di Pietro, Florencia, et al. An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z beta as an Essential Regulator of Spindle Orientation. ''Curr Biol''. 2017 Aug 21; '''27''' (16):2452-2464.e8
Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment.
Description: Reynolds, Daniel S, et al. Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment. ''Sci Rep''. 2017 Sep 4; '''7''' (1):10382
A V0 core neuronal circuit for inspiration.
Description: Wu, Jinjin, et al. A V0 core neuronal circuit for inspiration. ''Nat Commun''. 2017 Sep 15; '''8''' (1):544
WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in Caenorhabditiselegans embryos.
Description: Zhang, Yan, et al. WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in Caenorhabditiselegans embryos. ''Biol Open''. 2017 Sep 15; '''6''' (9):1324-1328
Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes.
Description: Fritz-Laylin, Lillian K, et al. Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes. ''Elife''. 2017 Sep 26; '''6''':
Giant light-harvesting nanoantenna for single-molecule detection in ambient light.
Description: Trofymchuk, Kateryna, et al. Giant light-harvesting nanoantenna for single-molecule detection in ambient light. ''Nat Photonics''. 2017 Oct; '''11''' (10):657-663
Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin.
Description: Huynh, Walter, et al. Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin. ''J Cell Biol''. 2017 Oct 2; '''216''' (10):3051-3060
COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal.
Description: Xu, Peng, et al. COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal. ''Elife''. 2017 Oct 23; '''6''':
On-demand optogenetic activation of human stem-cell-derived neurons.
Description: Klapper, Simon D, et al. On-demand optogenetic activation of human stem-cell-derived neurons. ''Sci Rep''. 2017 Oct 31; '''7''' (1):14450
Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.
Description: Perera, Ruwan K, et al. Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4. ''Sci Rep''. 2017 Nov 9; '''7''' (1):15222
Deep Phenotypic Mapping of Bacterial Cytoskeletal Mutants Reveals Physiological Robustness to Cell Size.
Description: Shi, Handuo, et al. Deep Phenotypic Mapping of Bacterial Cytoskeletal Mutants Reveals Physiological Robustness to Cell Size. ''Curr Biol''. 2017 Nov 20; '''27''' (22):3419-3429.e4
The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.
Description: Smith, Linda, et al. The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation. ''Sci Rep''. 2017 Nov 23; '''7''' (1):16115
Graphene-edge dielectrophoretic tweezers for trapping of biomolecules.
Description: Barik, Avijit, et al. Graphene-edge dielectrophoretic tweezers for trapping of biomolecules. ''Nat Commun''. 2017 Nov 30; '''8''' (1):1867
Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes.
Description: Loveless, Timothy, et al. Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes. ''Mol Biol Cell''. 2017 Dec 1; '''28''' (25):3621-3633
Ectopic expression of Pax4 in pancreatic delta cells results in beta-like cell neogenesis.
Description: Druelle, Noemie, et al. Ectopic expression of Pax4 in pancreatic delta cells results in beta-like cell neogenesis. ''J Cell Biol''. 2017 Dec 4; '''216''' (12):4299-4311
Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid.
Description: Steinberg, Ximena, et al. Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid. ''Elife''. 2017 Dec 5; '''6''':
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration.
Description: Nordenfelt, Pontus, et al. Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration. ''Nat Commun''. 2017 Dec 11; '''8''' (1):2047
Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2.
Description: Araujo, Jessica Alves de Medeiros, et al. Direct Reprogramming of Adult Human Somatic Stem Cells Into Functional Neurons Using Sox2, Ascl1, and Neurog2. ''Front Cell Neurosci''. 2018; '''12''': 155
HybTrack: A hybrid single particle tracking software using manual and automatic detection of dim signals.
Description: Lee, Byung Hun, et al. HybTrack: A hybrid single particle tracking software using manual and automatic detection of dim signals. ''Sci Rep''. 2018 Jan 9; '''8''' (1):212
Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells.
Description: Fowler, Casey C, et al. Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells. ''Cell Host Microbe''. 2018 Jan 10; '''23''' (1):65-76.e6
Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.
Description: Lopez-Baez, Juan Carlos, et al. Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair. ''Elife''. 2018 Feb 6; '''7''':
The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding.
Description: Zhou, Coral Y, et al. The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding. ''Mol Cell''. 2018 Feb 15; '''69''' (4):677-688.e9
Uncovering the balance of forces driving microtubule aster migration in C. elegans zygotes.
Description: De Simone, A, et al. Uncovering the balance of forces driving microtubule aster migration in C. elegans zygotes. ''Nat Commun''. 2018 Mar 5; '''9''' (1):938
Protein Kinase C Enhances Electrical Synaptic Transmission by Acting on Junctional and Postsynaptic Ca(2+) Currents.
Description: Beekharry, Christopher C, et al. Protein Kinase C Enhances Electrical Synaptic Transmission by Acting on Junctional and Postsynaptic Ca(2+) Currents. ''J Neurosci''. 2018 Mar 14; '''38''' (11):2796-2808
Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules.
Description: Martin, Maud, et al. Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules. ''Elife''. 2018 Mar 16; '''7''':
Competition between microtubule-associated proteins directs motor transport.
Description: Monroy, Brigette Y, et al. Competition between microtubule-associated proteins directs motor transport. ''Nat Commun''. 2018 Apr 16; '''9''' (1):1487
The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h.
Description: Gamarra, Nathan, et al. The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h. ''Elife''. 2018 Apr 17; '''7''':
A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons.
Description: Das, Sulagna, et al. A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons. ''Sci Adv''. 2018 Jun; '''4''' (6):eaar3448
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.
Description: McKinley, Kara L, et al. Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. ''Elife''. 2018 Jun 13; '''7''':
RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs.
Description: McClintock, Mark A, et al. RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs. ''Elife''. 2018 Jun 26; '''7''':
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
Description: Basu, Srinjan, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. ''Nat Commun''. 2018 Jun 28; '''9''' (1):2520
A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish.
Description: Wu, Roland S, et al. A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish. ''Dev Cell''. 2018 Jul 2; '''46''' (1):112-125.e4
Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure.
Description: Mortensen, Richard D, et al. Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure. ''G3 (Bethesda)''. 2018 Jul 2; '''8''' (7):2361-2387
Single-color, ratiometric biosensors for detecting signaling activities in live cells.
Description: Ross, Brian L, et al. Single-color, ratiometric biosensors for detecting signaling activities in live cells. ''Elife''. 2018 Jul 3; '''7''':
Structural analyses of FERM domain-mediated membrane localization of FARP1.
Description: Kuo, Yi-Chun, et al. Structural analyses of FERM domain-mediated membrane localization of FARP1. ''Sci Rep''. 2018 Jul 11; '''8''' (1):10477
Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription.
Description: Novais-Cruz, Marco, et al. Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription. ''Elife''. 2018 Aug 6; '''7''':
Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.
Description: Marques, Sueli, et al. Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development. ''Dev Cell''. 2018 Aug 20; '''46''' (4):504-517.e7
Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq.
Description: Munoz-Manchado, Ana B, et al. Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq. ''Cell Rep''. 2018 Aug 21; '''24''' (8):2179-2190.e7
SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System.
Description: Jones, Jeff R, et al. SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System. ''J Neurosci''. 2018 Sep 12; '''38''' (37):7986-7995
h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex.
Description: Kalmbach, Brian E, et al. h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex. ''Neuron''. 2018 Dec 5; '''100''' (5):1194-1208.e5