help > CONN multiple comparison correction
Nov 28, 2024  10:11 AM | Alexander Groessing
CONN multiple comparison correction

Dear CONN experts,


I am new to CONN and am currently doing an ROI to ROI analysis of a baseline. I correlate with behavioral outcome (SRS 2) and control for age. Between subject contrast [ 0 0 1]


We picked all possible ROIs (164) and chose all ROIs as targets in the 2nd level analysis. 


I'm wondering how the correction works precisely. We chose FDR at 0.05.


Is it corrected per source for 164 targets, which would be 164 tests, or for 164 sources, each having 164 targets? There would be some false positives in the first case, and we would need further correction. 


I should add that I go through the seeds in the list individually, but I am unsure of how CONN handles these corrections.


 


Thank you very much for your assistance.


Best regards


Alex


 

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TitleAuthorDate
CONN multiple comparison correction
Alexander Groessing Nov 28, 2024
Alexander Groessing Dec 9, 2024
Alfonso Nieto-Castanon Dec 4, 2024